Evaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening models

The aim of this study was therefore to evaluate the antioxidant and anti-diabesity potential of a hot water extract of C. maculata in non-cell based assays and correlate the activities with phenolic composition. Total antioxidant capacity (TAC) was assessed in terms of free radical scavenging and iron reducing ability. The DPPH, ABTS, ORAC and FRAP assays were employed. Anti-diabesity potential was assessed in terms of the inhibition of the digestive enzymes, α-glucosidase and pancreatic lipase

Grantor dc:publisher.institution

University of the Western Cape

Year dc:date.issued

2014

Author dc:creator

• Matrose, Albertina Neliswa

Advisors dc:contributor.advisor

• Syce, James A.
• Joubert, E
• Malherbe, C.J

• Obesity
• Diabetes
• Oxidative stress
• Cyclopia maculata
• Antioxidant capacity
• DPPH, ABTS, ORAC and FRAP
• Total polyphenol content
• Lipase inhibition
• α-Glucosidase inhibition
• Effect of fermentation
• HPLC-DAD-BCD

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