{"id":{"repo_id":"washington","oai_identifier":"oai:digital.lib.washington.edu:1773/26468"},"canonical_url":"https://search.dev.ndltd.org/etd/washington/oai:digital.lib.washington.edu:1773/26468","repository":{"repo_id":"washington","name":"University of Washington","base_url":"https://digital.lib.washington.edu/server/oai/request"},"display":{"title":"Association between Air Pollution Exposure and Self-Report of Recent Respiratory Infection: A MESA Air study","abstract":"Background: Ambient air pollution has been linked to multiple adverse health outcomes. Most of these studies have use large-scale models to estimate air pollution exposures and have identified health outcomes based on hospital diagnosis codes. The Multi-Ethnic Study of Atherosclerosis (MESA) and MESA Air provide residence-level air pollution data. We investigated the association between these data and information collected prospectively on recent MESA participant infection. Methods & Results: MESA, a prospective cohort study, followed over 6800 participants with 5 study visits over 12 years. Data collected included participant self-report of recent respiratory infection. Individual ambient air pollution exposures to fine particulate matter (PM2.5), oxides of nitrogen (NOx and NO2), and black carbon (BC) were estimated. Cross-sectional and longitudinal associations were examined with generalized linear models for each pollutant adjusted for confounders: study site, season of exam, age, sex, race/ethnicity, smoking, and socio-economic status. Across all study sites, air pollution exposure estimates decreased. Report of recent respiratory infection was associated with season, the highest prevalence in winter. Nearly 18% of participants reported infection during the 2 weeks prior to their visit. Significant associations were seen between increased prevalence of infection and elevated exposures to PM2.5, NOx, and NO2. Discussion: In a large population-based cohort study, we found robust evidence that the prevalence of respiratory infection is increased in participants exposed to higher levels of ambient air pollution.","abstract_html":"Background: Ambient air pollution has been linked to multiple adverse health outcomes. Most of these studies have use large-scale models to estimate air pollution exposures and have identified health outcomes based on hospital diagnosis codes. The Multi-Ethnic Study of Atherosclerosis (MESA) and MESA Air provide residence-level air pollution data. We investigated the association between these data and information collected prospectively on recent MESA participant infection. Methods & Results: MESA, a prospective cohort study, followed over 6800 participants with 5 study visits over 12 years. Data collected included participant self-report of recent respiratory infection. Individual ambient air pollution exposures to fine particulate matter (PM2.5), oxides of nitrogen (NOx and NO2), and black carbon (BC) were estimated. Cross-sectional and longitudinal associations were examined with generalized linear models for each pollutant adjusted for confounders: study site, season of exam, age, sex, race/ethnicity, smoking, and socio-economic status. Across all study sites, air pollution exposure estimates decreased. Report of recent respiratory infection was associated with season, the highest prevalence in winter. Nearly 18% of participants reported infection during the 2 weeks prior to their visit. Significant associations were seen between increased prevalence of infection and elevated exposures to PM2.5, NOx, and NO2. Discussion: In a large population-based cohort study, we found robust evidence that the prevalence of respiratory infection is increased in participants exposed to higher levels of ambient air pollution.","abstract_has_math":false,"creators":["Miller, Carly Marie"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Kaufman, Joel"],"committee_chairs":[],"committee_members":[],"year":2014,"date_issued":"2014-10-13","date_published":"2014-10-13","updated_at":"2026-07-24T05:58:18Z","subjects":["air pollution; infection; MESA"],"languages":["en_US"],"rights":["Copyright is held by the individual authors."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1773/26468","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Kaufman, Joel"]},{"key":"dc:creator","label":"Author","values":["Miller, Carly Marie"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-10-13T20:03:56Z"]},{"key":"dc:date.issued","label":"Date","values":["2014-10-13"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["air pollution; infection; MESA"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright is held by the individual authors."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["Miller_washington_0250O_13449.pdf"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/1773/26468"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Thesis (Master's)--University of Washington, 2014"]},{"key":"dc:description.abstract","label":"Abstract","values":["Background: Ambient air pollution has been linked to multiple adverse health outcomes. Most of these studies have use large-scale models to estimate air pollution exposures and have identified health outcomes based on hospital diagnosis codes. The Multi-Ethnic Study of Atherosclerosis (MESA) and MESA Air provide residence-level air pollution data. We investigated the association between these data and information collected prospectively on recent MESA participant infection. Methods & Results: MESA, a prospective cohort study, followed over 6800 participants with 5 study visits over 12 years. Data collected included participant self-report of recent respiratory infection. Individual ambient air pollution exposures to fine particulate matter (PM2.5), oxides of nitrogen (NOx and NO2), and black carbon (BC) were estimated. Cross-sectional and longitudinal associations were examined with generalized linear models for each pollutant adjusted for confounders: study site, season of exam, age, sex, race/ethnicity, smoking, and socio-economic status. Across all study sites, air pollution exposure estimates decreased. Report of recent respiratory infection was associated with season, the highest prevalence in winter. Nearly 18% of participants reported infection during the 2 weeks prior to their visit. Significant associations were seen between increased prevalence of infection and elevated exposures to PM2.5, NOx, and NO2. Discussion: In a large population-based cohort study, we found robust evidence that the prevalence of respiratory infection is increased in participants exposed to higher levels of ambient air pollution."]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Association between Air Pollution Exposure and Self-Report of Recent Respiratory Infection: A MESA Air study"]}]}],"canonical_facts":{"dc:contributor.advisor":["Kaufman, Joel"],"dc:creator":["Miller, Carly Marie"],"dc:date.accessioned":["2014-10-13T20:03:56Z"],"dc:date.issued":["2014-10-13"],"dc:description":["Thesis (Master's)--University of Washington, 2014"],"dc:description.abstract":["Background: Ambient air pollution has been linked to multiple adverse health outcomes. Most of these studies have use large-scale models to estimate air pollution exposures and have identified health outcomes based on hospital diagnosis codes. The Multi-Ethnic Study of Atherosclerosis (MESA) and MESA Air provide residence-level air pollution data. We investigated the association between these data and information collected prospectively on recent MESA participant infection. Methods & Results: MESA, a prospective cohort study, followed over 6800 participants with 5 study visits over 12 years. Data collected included participant self-report of recent respiratory infection. Individual ambient air pollution exposures to fine particulate matter (PM2.5), oxides of nitrogen (NOx and NO2), and black carbon (BC) were estimated. Cross-sectional and longitudinal associations were examined with generalized linear models for each pollutant adjusted for confounders: study site, season of exam, age, sex, race/ethnicity, smoking, and socio-economic status. Across all study sites, air pollution exposure estimates decreased. Report of recent respiratory infection was associated with season, the highest prevalence in winter. Nearly 18% of participants reported infection during the 2 weeks prior to their visit. Significant associations were seen between increased prevalence of infection and elevated exposures to PM2.5, NOx, and NO2. Discussion: In a large population-based cohort study, we found robust evidence that the prevalence of respiratory infection is increased in participants exposed to higher levels of ambient air pollution."],"dc:format.mimetype":["application/pdf"],"dc:identifier.other":["Miller_washington_0250O_13449.pdf"],"dc:identifier.uri":["http://hdl.handle.net/1773/26468"],"dc:language.iso":["en_US"],"dc:rights":["Copyright is held by the individual authors."],"dc:subject":["air pollution; infection; MESA"],"dc:title":["Association between Air Pollution Exposure and Self-Report of Recent Respiratory Infection: A MESA Air study"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T05:58:18Z"}