{"id":{"repo_id":"vu-aus","oai_identifier":"oai:eprints.vu.edu.au:15598"},"canonical_url":"https://search.dev.ndltd.org/etd/vu-aus/oai:eprints.vu.edu.au:15598","repository":{"repo_id":"vu-aus","name":"Victoria University (Australia)","base_url":"https://vuir.vu.edu.au/cgi/oai2"},"display":{"title":"Factors affecting the excitability of skinned fibres of the rat","abstract":"During the last decade, the rat mechanically skinned fibre preparation has been used with increasing frequency to investigate cellular aspects of excitation-contraction (EC) coupling processes in mammalian skeletal muscle. The main aim of this thesis was to increase awareness of factors that affect the contractile responsiveness of rat mechanically skinned fibre preparations to T-system depolarization, a functional parameter of E-C coupling referred to, sometimes, as skinned fibre excitability. More specifically, the work presented in this thesis is concerned with the relationship between rat skinned fibre excitability and (i) developmental age, (ii) MHC composition, muscle of origin and (iii) glycogen content.","abstract_html":"During the last decade, the rat mechanically skinned fibre preparation has been used with increasing frequency to investigate cellular aspects of excitation-contraction (EC) coupling processes in mammalian skeletal muscle. The main aim of this thesis was to increase awareness of factors that affect the contractile responsiveness of rat mechanically skinned fibre preparations to T-system depolarization, a functional parameter of E-C coupling referred to, sometimes, as skinned fibre excitability. More specifically, the work presented in this thesis is concerned with the relationship between rat skinned fibre excitability and (i) developmental age, (ii) MHC composition, muscle of origin and (iii) glycogen content.","abstract_has_math":false,"creators":["Goodman, Craig"],"institution":"Victoria University","degree_name":"phd","degree_level":"doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2003,"date_issued":"2003","date_published":"2003","updated_at":"2026-07-24T06:33:15Z","subjects":["1004 Medical Biotechnology","School of Biomedical and Health Sciences"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Goodman, Craig"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2003"]},{"key":"dc:date.issued","label":"Date","values":["2003"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["School of Biomedical Sciences"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["Victoria University"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://vuir.vu.edu.au/15598/"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["phd"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["1004 Medical Biotechnology","School of Biomedical and Health Sciences"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://vuir.vu.edu.au/15598/3/GOODMAN%20Craig-thesis_nosignature.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["During the last decade, the rat mechanically skinned fibre preparation has been used with increasing frequency to investigate cellular aspects of excitation-contraction (EC) coupling processes in mammalian skeletal muscle. The main aim of this thesis was to increase awareness of factors that affect the contractile responsiveness of rat mechanically skinned fibre preparations to T-system depolarization, a functional parameter of E-C coupling referred to, sometimes, as skinned fibre excitability. More specifically, the work presented in this thesis is concerned with the relationship between rat skinned fibre excitability and (i) developmental age, (ii) MHC composition, muscle of origin and (iii) glycogen content."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Factors affecting the excitability of skinned fibres of the rat"]}]}],"canonical_facts":{"dc:creator":["Goodman, Craig"],"dc:date":["2003"],"dc:date.issued":["2003"],"dc:description.abstract":["During the last decade, the rat mechanically skinned fibre preparation has been used with increasing frequency to investigate cellular aspects of excitation-contraction (EC) coupling processes in mammalian skeletal muscle. The main aim of this thesis was to increase awareness of factors that affect the contractile responsiveness of rat mechanically skinned fibre preparations to T-system depolarization, a functional parameter of E-C coupling referred to, sometimes, as skinned fibre excitability. More specifically, the work presented in this thesis is concerned with the relationship between rat skinned fibre excitability and (i) developmental age, (ii) MHC composition, muscle of origin and (iii) glycogen content."],"dc:format":["text"],"dc:identifier.uri":["https://vuir.vu.edu.au/15598/3/GOODMAN%20Craig-thesis_nosignature.pdf"],"dc:language":["en"],"dc:publisher.department":["School of Biomedical Sciences"],"dc:publisher.institution":["Victoria University"],"dc:relation.isreferencedby":["https://vuir.vu.edu.au/15598/"],"dc:subject":["1004 Medical Biotechnology","School of Biomedical and Health Sciences"],"dc:title":["Factors affecting the excitability of skinned fibres of the rat"],"dc:type":["Thesis"],"dc:type.qualificationlevel":["doctoral"],"dc:type.qualificationname":["phd"]},"updated_at":"2026-07-24T06:33:15Z"}