{"id":{"repo_id":"vu-aus","oai_identifier":"oai:eprints.vu.edu.au:15592"},"canonical_url":"https://search.dev.ndltd.org/etd/vu-aus/oai:eprints.vu.edu.au:15592","repository":{"repo_id":"vu-aus","name":"Victoria University (Australia)","base_url":"https://vuir.vu.edu.au/cgi/oai2"},"display":{"title":"Investigation of the oxytocin receptor gene in sheep","abstract":"The increase in uterine oxytocin receptor (OTR)concentrations over the late luteal phase of the estrous cycle in sheep is thought to play an important role in the regulation of the cycle length by facilitating the effect of oxytocin on uterine prostaglandin release. At the end of pregnancy, a dramatic increase in the number of OTR also indicates the importance for OTR in the process of labor. In order to study the mechanisms underlying the resolution of OTR expression, the aim of this study was to obtain and characterise OTR cDNA and OTR gene transcripts, to determine the OTR gene expression level in different tissue types, to investigate the role of exogenous steroids in the regulation of OTR gene expression, and to develop a gene expression system for OTR protein.","abstract_html":"The increase in uterine oxytocin receptor (OTR)concentrations over the late luteal phase of the estrous cycle in sheep is thought to play an important role in the regulation of the cycle length by facilitating the effect of oxytocin on uterine prostaglandin release. At the end of pregnancy, a dramatic increase in the number of OTR also indicates the importance for OTR in the process of labor. In order to study the mechanisms underlying the resolution of OTR expression, the aim of this study was to obtain and characterise OTR cDNA and OTR gene transcripts, to determine the OTR gene expression level in different tissue types, to investigate the role of exogenous steroids in the regulation of OTR gene expression, and to develop a gene expression system for OTR protein.","abstract_has_math":false,"creators":["Feng, Helen Chunying"],"institution":"Victoria University of Technology","degree_name":"phd","degree_level":"doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2000,"date_issued":"2000","date_published":"2000","updated_at":"2026-07-24T06:33:15Z","subjects":["0702 Animal Production","0604 Genetics","School of Engineering and Science"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Feng, Helen Chunying"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2000"]},{"key":"dc:date.issued","label":"Date","values":["2000"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Centre for Bioprocessing and Food Technology"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["Victoria University of Technology"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://vuir.vu.edu.au/15592/"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["phd"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["0702 Animal Production","0604 Genetics","School of Engineering and Science"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://vuir.vu.edu.au/15592/1/Feng_2000compressed.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The increase in uterine oxytocin receptor (OTR)concentrations over the late luteal phase of the estrous cycle in sheep is thought to play an important role in the regulation of the cycle length by facilitating the effect of oxytocin on uterine prostaglandin release. At the end of pregnancy, a dramatic increase in the number of OTR also indicates the importance for OTR in the process of labor. In order to study the mechanisms underlying the resolution of OTR expression, the aim of this study was to obtain and characterise OTR cDNA and OTR gene transcripts, to determine the OTR gene expression level in different tissue types, to investigate the role of exogenous steroids in the regulation of OTR gene expression, and to develop a gene expression system for OTR protein."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Investigation of the oxytocin receptor gene in sheep"]}]}],"canonical_facts":{"dc:creator":["Feng, Helen Chunying"],"dc:date":["2000"],"dc:date.issued":["2000"],"dc:description.abstract":["The increase in uterine oxytocin receptor (OTR)concentrations over the late luteal phase of the estrous cycle in sheep is thought to play an important role in the regulation of the cycle length by facilitating the effect of oxytocin on uterine prostaglandin release. At the end of pregnancy, a dramatic increase in the number of OTR also indicates the importance for OTR in the process of labor. In order to study the mechanisms underlying the resolution of OTR expression, the aim of this study was to obtain and characterise OTR cDNA and OTR gene transcripts, to determine the OTR gene expression level in different tissue types, to investigate the role of exogenous steroids in the regulation of OTR gene expression, and to develop a gene expression system for OTR protein."],"dc:format":["text"],"dc:identifier.uri":["https://vuir.vu.edu.au/15592/1/Feng_2000compressed.pdf"],"dc:language":["en"],"dc:publisher.department":["Centre for Bioprocessing and Food Technology"],"dc:publisher.institution":["Victoria University of Technology"],"dc:relation.isreferencedby":["https://vuir.vu.edu.au/15592/"],"dc:subject":["0702 Animal Production","0604 Genetics","School of Engineering and Science"],"dc:title":["Investigation of the oxytocin receptor gene in sheep"],"dc:type":["Thesis"],"dc:type.qualificationlevel":["doctoral"],"dc:type.qualificationname":["phd"]},"updated_at":"2026-07-24T06:33:15Z"}