{"id":{"repo_id":"vu-aus","oai_identifier":"oai:eprints.vu.edu.au:15368"},"canonical_url":"https://search.dev.ndltd.org/etd/vu-aus/oai:eprints.vu.edu.au:15368","repository":{"repo_id":"vu-aus","name":"Victoria University (Australia)","base_url":"https://vuir.vu.edu.au/cgi/oai2"},"display":{"title":"Effects of altered physical activity on human skeletal muscle sarcoplasmic reticulum calcium regulation","abstract":"The sarcoplasmic reticulum (SR) regulates intracellular calcium and therefore largely determines the rates of contraction and relaxation in skeletal muscle. However, little is known about SR function in human skeletal muscle. This thesis therefore investigated several factors that could potentially influence SR function in human skeletal muscle, including the effects of acute exercise, training status, chronic inactivity and the influence of muscle fibre type. A final study investigated the effects of an immunosuppressive drug on SR function in rat skeletal muscle.","abstract_html":"The sarcoplasmic reticulum (SR) regulates intracellular calcium and therefore largely determines the rates of contraction and relaxation in skeletal muscle. However, little is known about SR function in human skeletal muscle. This thesis therefore investigated several factors that could potentially influence SR function in human skeletal muscle, including the effects of acute exercise, training status, chronic inactivity and the influence of muscle fibre type. A final study investigated the effects of an immunosuppressive drug on SR function in rat skeletal muscle.","abstract_has_math":false,"creators":["Li, Jia Li"],"institution":"Victoria University of Technology","degree_name":"phd","degree_level":"doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1999,"date_issued":"1999","date_published":"1999","updated_at":"2026-07-24T06:33:09Z","subjects":["School of Sport and Exercise Science","1106 Human Movement and Sports Science"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Li, Jia Li"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1999"]},{"key":"dc:date.issued","label":"Date","values":["1999"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Human Movement, Recreation and Performance"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["Victoria University of Technology"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://vuir.vu.edu.au/15368/"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["phd"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["School of Sport and Exercise Science","1106 Human Movement and Sports Science"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://vuir.vu.edu.au/15368/1/Li_Li_1999compressed.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The sarcoplasmic reticulum (SR) regulates intracellular calcium and therefore largely determines the rates of contraction and relaxation in skeletal muscle. However, little is known about SR function in human skeletal muscle. This thesis therefore investigated several factors that could potentially influence SR function in human skeletal muscle, including the effects of acute exercise, training status, chronic inactivity and the influence of muscle fibre type. A final study investigated the effects of an immunosuppressive drug on SR function in rat skeletal muscle."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Effects of altered physical activity on human skeletal muscle sarcoplasmic reticulum calcium regulation"]}]}],"canonical_facts":{"dc:creator":["Li, Jia Li"],"dc:date":["1999"],"dc:date.issued":["1999"],"dc:description.abstract":["The sarcoplasmic reticulum (SR) regulates intracellular calcium and therefore largely determines the rates of contraction and relaxation in skeletal muscle. However, little is known about SR function in human skeletal muscle. This thesis therefore investigated several factors that could potentially influence SR function in human skeletal muscle, including the effects of acute exercise, training status, chronic inactivity and the influence of muscle fibre type. 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