{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/90957"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/90957","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Nutrition in relation to coremia and spore production in Penicillium clavigerum","abstract":"A defined medium containing glucose, mineral salts; and the amino acid L-proline was developed for the propagation of Penicillium clavigerum. Certain modifications of this medium produce dramatic differences in colonial morphology. Coremia are produced only if certain dipeptides are added to the medium. The dipeptides shown to produce this response were DL-alpha aminobutyric acid-DL-leucine, DL-leucyl-DL-alanine, DL-alanylglycine, and glycyl-DLaspartic acid. No sporophores were produced in the absence of these dipeptides, nor was dry weight affected. The fungus does not require vitamins for growth, but the addition of folic acid to the medium increased the quantity of spores and coremia.","abstract_html":"A defined medium containing glucose, mineral salts; and the amino acid L-proline was developed for the propagation of Penicillium clavigerum. Certain modifications of this medium produce dramatic differences in colonial morphology. Coremia are produced only if certain dipeptides are added to the medium. The dipeptides shown to produce this response were DL-alpha aminobutyric acid-DL-leucine, DL-leucyl-DL-alanine, DL-alanylglycine, and glycyl-DLaspartic acid. No sporophores were produced in the absence of these dipeptides, nor was dry weight affected. The fungus does not require vitamins for growth, but the addition of folic acid to the medium increased the quantity of spores and coremia.","abstract_has_math":false,"creators":["Tinnell, Wayne Houston"],"institution":"Virginia Polytechnic Institute","degree_name":"M.S.","degree_level":"masters","degree_discipline":"Microbiology","degree_department":"Microbiology","school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1967,"date_issued":"1967","date_published":"1967","updated_at":"2026-07-22T22:19:01Z","subjects":[],"languages":["en"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10919/90957","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.department","label":"Department","values":["Microbiology"]},{"key":"dc:creator","label":"Author","values":["Tinnell, Wayne Houston"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2019-07-03T16:42:46Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2019-07-03T16:42:46Z"]},{"key":"dc:date.issued","label":"Date","values":["1967"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Polytechnic Institute"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Microbiology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/90957"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["A defined medium containing glucose, mineral salts; and the amino acid L-proline was developed for the propagation of Penicillium clavigerum. Certain modifications of this medium produce dramatic differences in colonial morphology. Coremia are produced only if certain dipeptides are added to the medium. The dipeptides shown to produce this response were DL-alpha aminobutyric acid-DL-leucine, DL-leucyl-DL-alanine, DL-alanylglycine, and glycyl-DLaspartic acid. No sporophores were produced in the absence of these dipeptides, nor was dry weight affected. The fungus does not require vitamins for growth, but the addition of folic acid to the medium increased the quantity of spores and coremia."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["M.S."]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Nutrition in relation to coremia and spore production in Penicillium clavigerum"]}]}],"canonical_facts":{"dc:contributor.department":["Microbiology"],"dc:creator":["Tinnell, Wayne Houston"],"dc:date.accessioned":["2019-07-03T16:42:46Z"],"dc:date.available":["2019-07-03T16:42:46Z"],"dc:date.issued":["1967"],"dc:description.abstract":["A defined medium containing glucose, mineral salts; and the amino acid L-proline was developed for the propagation of Penicillium clavigerum. Certain modifications of this medium produce dramatic differences in colonial morphology. Coremia are produced only if certain dipeptides are added to the medium. The dipeptides shown to produce this response were DL-alpha aminobutyric acid-DL-leucine, DL-leucyl-DL-alanine, DL-alanylglycine, and glycyl-DLaspartic acid. No sporophores were produced in the absence of these dipeptides, nor was dry weight affected. The fungus does not require vitamins for growth, but the addition of folic acid to the medium increased the quantity of spores and coremia."],"dc:description.degree":["M.S."],"dc:format.mimetype":["application/pdf"],"dc:identifier.uri":["http://hdl.handle.net/10919/90957"],"dc:language.iso":["en"],"dc:publisher":["Virginia Polytechnic Institute"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:title":["Nutrition in relation to coremia and spore production in Penicillium clavigerum"],"dc:type":["Thesis"],"dc:type.dcmitype":["Text"],"thesis:degree_discipline":["Microbiology"],"thesis:degree_level":["masters"],"thesis:degree_name":["M.S."],"thesis:institution_name":["Virginia Polytechnic Institute"]},"updated_at":"2026-07-22T22:19:01Z"}