{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/80117"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/80117","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Glucose clearance studies in lactating cows: influence of stage of lactation and ration composition","abstract":"Glucose pool size (PS), pool space (PV) and clearance rate (CR) vere determined for eight first-lactation Holstein cows at three lactation stages [early (E) = 75-100 days, late (L) = 205-250 days, and dry (D) ]. A corn silage-based ration (15% CP, 22% ADP) was fed ad libitum during lactation and at maintenance during D, using 4-hr feeding intervals. Three intravenous glucose (.1 g/kg BW) injections were administered each period. Serial blood samples were collected for 40 min post-dosing. Parameters were calculated by the least squares method using natural logarithms of glucose concentration. Basal plasma glucose and insulin concentrations were 57.4, 60.1, and 62.3 mg/dl and .78, .97, and 1.24 ng/ml, respectively, for E, L, and D, respectively. PS and PV increased (P<.05) from E to D; however, when adjusted for body weight there was no difference across stages. CR decreased (P<.05) from E (2.43%/min) to D (1.71%/min) and was correlated with dry matter intake (r = .70, P<.01). Glucose-induced insulin response was greater (P<.05) during D than during lactation due to higher peak (P<.05) and lover insulin clearance (P<.05) values. Glucose parameters were determined by single injection in lactating cows fed a high-concentrate ration (16.8% CP, 13% ADF) (n=5) and a control ration (16.3% CP, 24.4% ADF) (n=4) , at 90 and 120 days postpartum. No differences due to stage or diet were observed, due to insufficient observations. Plasma glucose and insulin tended to be higher with HC-feeding and at the later stage.","abstract_html":"Glucose pool size (PS), pool space (PV) and clearance rate (CR) vere determined for eight first-lactation Holstein cows at three lactation stages [early (E) = 75-100 days, late (L) = 205-250 days, and dry (D) ]. A corn silage-based ration (15% CP, 22% ADP) was fed ad libitum during lactation and at maintenance during D, using 4-hr feeding intervals. Three intravenous glucose (.1 g/kg BW) injections were administered each period. Serial blood samples were collected for 40 min post-dosing. Parameters were calculated by the least squares method using natural logarithms of glucose concentration. Basal plasma glucose and insulin concentrations were 57.4, 60.1, and 62.3 mg/dl and .78, .97, and 1.24 ng/ml, respectively, for E, L, and D, respectively. PS and PV increased (P&lt;.05) from E to D; however, when adjusted for body weight there was no difference across stages. CR decreased (P&lt;.05) from E (2.43%/min) to D (1.71%/min) and was correlated with dry matter intake (r = .70, P&lt;.01). Glucose-induced insulin response was greater (P&lt;.05) during D than during lactation due to higher peak (P&lt;.05) and lover insulin clearance (P&lt;.05) values. Glucose parameters were determined by single injection in lactating cows fed a high-concentrate ration (16.8% CP, 13% ADF) (n=5) and a control ration (16.3% CP, 24.4% ADF) (n=4) , at 90 and 120 days postpartum. No differences due to stage or diet were observed, due to insufficient observations. Plasma glucose and insulin tended to be higher with HC-feeding and at the later stage.","abstract_has_math":false,"creators":["Gebhart, Melanie K."],"institution":"Virginia Polytechnic Institute and State University","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Dairy Science","degree_department":"Dairy Science","school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1982,"date_issued":"1982","date_published":"1982","updated_at":"2026-07-22T22:20:03Z","subjects":[],"languages":["en_US"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10919/80117","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.department","label":"Department","values":["Dairy Science"]},{"key":"dc:creator","label":"Author","values":["Gebhart, Melanie K."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2017-11-09T21:08:58Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2017-11-09T21:08:58Z"]},{"key":"dc:date.issued","label":"Date","values":["1982"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Polytechnic Institute and State University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Dairy Science"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/80117"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Glucose pool size (PS), pool space (PV) and clearance rate (CR) vere determined for eight first-lactation Holstein cows at three lactation stages [early (E) = 75-100 days, late (L) = 205-250 days, and dry (D) ]. A corn silage-based ration (15% CP, 22% ADP) was fed ad libitum during lactation and at maintenance during D, using 4-hr feeding intervals. Three intravenous glucose (.1 g/kg BW) injections were administered each period. Serial blood samples were collected for 40 min post-dosing. Parameters were calculated by the least squares method using natural logarithms of glucose concentration. Basal plasma glucose and insulin concentrations were 57.4, 60.1, and 62.3 mg/dl and .78, .97, and 1.24 ng/ml, respectively, for E, L, and D, respectively. PS and PV increased (P<.05) from E to D; however, when adjusted for body weight there was no difference across stages. CR decreased (P<.05) from E (2.43%/min) to D (1.71%/min) and was correlated with dry matter intake (r = .70, P<.01). Glucose-induced insulin response was greater (P<.05) during D than during lactation due to higher peak (P<.05) and lover insulin clearance (P<.05) values. Glucose parameters were determined by single injection in lactating cows fed a high-concentrate ration (16.8% CP, 13% ADF) (n=5) and a control ration (16.3% CP, 24.4% ADF) (n=4) , at 90 and 120 days postpartum. No differences due to stage or diet were observed, due to insufficient observations. Plasma glucose and insulin tended to be higher with HC-feeding and at the later stage."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Glucose clearance studies in lactating cows: influence of stage of lactation and ration composition"]}]}],"canonical_facts":{"dc:contributor.department":["Dairy Science"],"dc:creator":["Gebhart, Melanie K."],"dc:date.accessioned":["2017-11-09T21:08:58Z"],"dc:date.available":["2017-11-09T21:08:58Z"],"dc:date.issued":["1982"],"dc:description.abstract":["Glucose pool size (PS), pool space (PV) and clearance rate (CR) vere determined for eight first-lactation Holstein cows at three lactation stages [early (E) = 75-100 days, late (L) = 205-250 days, and dry (D) ]. A corn silage-based ration (15% CP, 22% ADP) was fed ad libitum during lactation and at maintenance during D, using 4-hr feeding intervals. Three intravenous glucose (.1 g/kg BW) injections were administered each period. Serial blood samples were collected for 40 min post-dosing. Parameters were calculated by the least squares method using natural logarithms of glucose concentration. Basal plasma glucose and insulin concentrations were 57.4, 60.1, and 62.3 mg/dl and .78, .97, and 1.24 ng/ml, respectively, for E, L, and D, respectively. PS and PV increased (P<.05) from E to D; however, when adjusted for body weight there was no difference across stages. CR decreased (P<.05) from E (2.43%/min) to D (1.71%/min) and was correlated with dry matter intake (r = .70, P<.01). Glucose-induced insulin response was greater (P<.05) during D than during lactation due to higher peak (P<.05) and lover insulin clearance (P<.05) values. Glucose parameters were determined by single injection in lactating cows fed a high-concentrate ration (16.8% CP, 13% ADF) (n=5) and a control ration (16.3% CP, 24.4% ADF) (n=4) , at 90 and 120 days postpartum. No differences due to stage or diet were observed, due to insufficient observations. Plasma glucose and insulin tended to be higher with HC-feeding and at the later stage."],"dc:description.degree":["Master of Science"],"dc:format.mimetype":["application/pdf"],"dc:identifier.uri":["http://hdl.handle.net/10919/80117"],"dc:language.iso":["en_US"],"dc:publisher":["Virginia Polytechnic Institute and State University"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:title":["Glucose clearance studies in lactating cows: influence of stage of lactation and ration composition"],"dc:type":["Thesis"],"dc:type.dcmitype":["Text"],"thesis:degree_discipline":["Dairy Science"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Science"],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-22T22:20:03Z"}