{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/76244"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/76244","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Trace element concentrations in melanotic swine","abstract":"It is believed that the presence of certain trace elements in the skin may play an important role in the formation of melanomas. In this work, neutron activation analysis and x-ray fluorescence analysis were used to determine trace element concentrations in cancerous, noncancerous and normal swine skin samples and in non-cancerous and normal swine tissue samples. In-vivo x-ray fluorescence analysis was also used to determine trace element concentrations in cancerous, non-cancerous, and normal swine skin. Data on forty-eight trace elements in each sample were obtained and correlated. The limited number of cancerous samples made definitive conclusions about trace element imbalances uncertain. Nevertheless, the in-vivo XRFA method was shown to be a very useful method for trace element determination. Additionally, good base line data were obtained for trace element concentrations in a variety of organs of Sinclair miniature swine.","abstract_html":"It is believed that the presence of certain trace elements in the skin may play an important role in the formation of melanomas. In this work, neutron activation analysis and x-ray fluorescence analysis were used to determine trace element concentrations in cancerous, noncancerous and normal swine skin samples and in non-cancerous and normal swine tissue samples. In-vivo x-ray fluorescence analysis was also used to determine trace element concentrations in cancerous, non-cancerous, and normal swine skin. Data on forty-eight trace elements in each sample were obtained and correlated. The limited number of cancerous samples made definitive conclusions about trace element imbalances uncertain. Nevertheless, the in-vivo XRFA method was shown to be a very useful method for trace element determination. Additionally, good base line data were obtained for trace element concentrations in a variety of organs of Sinclair miniature swine.","abstract_has_math":false,"creators":["Sherman, Roseanne Marie"],"institution":"Virginia Polytechnic Institute and State University","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Nuclear Science and Engineering","degree_department":"Nuclear Science and Engineering","school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1982,"date_issued":"1982","date_published":"1982","updated_at":"2026-07-22T22:20:41Z","subjects":[],"languages":["en_US"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10919/76244","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.department","label":"Department","values":["Nuclear Science and Engineering"]},{"key":"dc:creator","label":"Author","values":["Sherman, Roseanne Marie"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2017-03-10T20:13:39Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2017-03-10T20:13:39Z"]},{"key":"dc:date.issued","label":"Date","values":["1982"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Polytechnic Institute and State University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Nuclear Science and Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/76244"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["It is believed that the presence of certain trace elements in the skin may play an important role in the formation of melanomas. In this work, neutron activation analysis and x-ray fluorescence analysis were used to determine trace element concentrations in cancerous, noncancerous and normal swine skin samples and in non-cancerous and normal swine tissue samples. In-vivo x-ray fluorescence analysis was also used to determine trace element concentrations in cancerous, non-cancerous, and normal swine skin. Data on forty-eight trace elements in each sample were obtained and correlated. The limited number of cancerous samples made definitive conclusions about trace element imbalances uncertain. Nevertheless, the in-vivo XRFA method was shown to be a very useful method for trace element determination. Additionally, good base line data were obtained for trace element concentrations in a variety of organs of Sinclair miniature swine."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Trace element concentrations in melanotic swine"]}]}],"canonical_facts":{"dc:contributor.department":["Nuclear Science and Engineering"],"dc:creator":["Sherman, Roseanne Marie"],"dc:date.accessioned":["2017-03-10T20:13:39Z"],"dc:date.available":["2017-03-10T20:13:39Z"],"dc:date.issued":["1982"],"dc:description.abstract":["It is believed that the presence of certain trace elements in the skin may play an important role in the formation of melanomas. In this work, neutron activation analysis and x-ray fluorescence analysis were used to determine trace element concentrations in cancerous, noncancerous and normal swine skin samples and in non-cancerous and normal swine tissue samples. In-vivo x-ray fluorescence analysis was also used to determine trace element concentrations in cancerous, non-cancerous, and normal swine skin. Data on forty-eight trace elements in each sample were obtained and correlated. The limited number of cancerous samples made definitive conclusions about trace element imbalances uncertain. Nevertheless, the in-vivo XRFA method was shown to be a very useful method for trace element determination. 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