Biotribology: articular cartilage friction, wear, and lubrication

This study developed, explored, and refined techniques for the in vitro study of cartilage-on-cartilage friction, deformation, and wear. Preliminary results of in vitro cartilage-on- cartilage experiments with emphasis on wear and biochemistry are presented. Cartilage-bone specimens were obtained from the stifle joints of steers from a separate controlled study. The load, sliding speed, and traverse of the lower specimens were held constant as lubricant and test length were varied. Lubricants tested consisted of a phosphate buffered saline solution, bovine serum, and bovine synovial fluid. Synovial fluid as a lubricant produced the least amount of damage to the cartilage. Serum produced more wear and damage than synovial fluid, but less than buffered saline (which produced the most damage). Three-hour tests produced more wear than one-hour tests, with severe damage to the lower plug in several of the three-hour tests. Analysis of the results was possible through: data acquisition of normal load, tangential load, and LVDT displacement; photomacrographs; ESEM and SEM surface studies; stained cross-sectional slides of cartilage; and hydroxyproline analysis of cartilage wear. Detailed procedures and discussion of results are presented along with recommended changes for future biotribology research.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Mechanical Engineering

Department dc:contributor.department

Mechanical Engineering

Grantor dc:publisher

Virginia Tech

Year dc:date.issued

1995

Author dc:creator

• Schroeder, Matthew O.

Chair dc:contributor.committeechair

• Furey, Michael J.

Committee members dc:contributor.committeemember

• Eiss, Norman S. Jr.
• Viet, Hugo P.

• Lubricants
• joint disease

Statement dc:rights

• In Copyright

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Language dc:language.iso

en

Dc Identifier Other

etd-12302008-063639

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/46457