{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/45655"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/45655","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"The action of selenite on ATP synthesis in rat lens","abstract":"A subcutaneous injection of sodium selenite (30 umol/kg body weight) in 10â day old rats produced a cataract within 72 hours. Lens opacification was preceded by a 15% decrease in ATP content. Lens ATP did not fully recover to control concentrations by 11 days post-injection. A moderate correlation existed between lens weight and total ATP content in control lenses <r=O.509, n=153), but this relationship disappeared with selenite treatment <r=0.023, n=153). There was a significant inhibition by selenite on lens growth from 4 through 11 days after an injection.","abstract_html":"A subcutaneous injection of sodium selenite (30 umol/kg body weight) in 10â day old rats produced a cataract within 72 hours. Lens opacification was preceded by a 15% decrease in ATP content. Lens ATP did not fully recover to control concentrations by 11 days post-injection. A moderate correlation existed between lens weight and total ATP content in control lenses &lt;r=O.509, n=153), but this relationship disappeared with selenite treatment &lt;r=0.023, n=153). There was a significant inhibition by selenite on lens growth from 4 through 11 days after an injection.","abstract_has_math":false,"creators":["Adamchak, Marsha Ann"],"institution":"Virginia Tech","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Biochemistry and Nutrition","degree_department":"Biochemistry and Nutrition","school":null,"contributors":[],"advisors":[],"committee_chairs":["Hess, John L."],"committee_members":["Bunce, George Edwin","Gregory, Eugene M."],"year":1986,"date_issued":"1986-09-15","date_published":"1986-09-15","updated_at":"2026-07-24T05:55:57Z","subjects":[],"languages":["en"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-11142012-040119"],"render_values":[{"text":"etd-11142012-040119","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/45655","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["Hess, John L."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Bunce, George Edwin","Gregory, Eugene M."]},{"key":"dc:contributor.department","label":"Department","values":["Biochemistry and Nutrition"]},{"key":"dc:creator","label":"Author","values":["Adamchak, Marsha Ann"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-03-14T21:49:34Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-03-14T21:49:34Z","2012-11-14"]},{"key":"dc:date.issued","label":"Date","values":["1986-09-15"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Tech"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biochemistry and Nutrition"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-11142012-040119"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/45655"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["A subcutaneous injection of sodium selenite (30 umol/kg body weight) in 10â day old rats produced a cataract within 72 hours. Lens opacification was preceded by a 15% decrease in ATP content. Lens ATP did not fully recover to control concentrations by 11 days post-injection. A moderate correlation existed between lens weight and total ATP content in control lenses <r=O.509, n=153), but this relationship disappeared with selenite treatment <r=0.023, n=153). There was a significant inhibition by selenite on lens growth from 4 through 11 days after an injection."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["BTD"]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["The action of selenite on ATP synthesis in rat lens"]}]}],"canonical_facts":{"dc:contributor.committeechair":["Hess, John L."],"dc:contributor.committeemember":["Bunce, George Edwin","Gregory, Eugene M."],"dc:contributor.department":["Biochemistry and Nutrition"],"dc:creator":["Adamchak, Marsha Ann"],"dc:date.accessioned":["2014-03-14T21:49:34Z"],"dc:date.available":["2014-03-14T21:49:34Z","2012-11-14"],"dc:date.issued":["1986-09-15"],"dc:description.abstract":["A subcutaneous injection of sodium selenite (30 umol/kg body weight) in 10â day old rats produced a cataract within 72 hours. Lens opacification was preceded by a 15% decrease in ATP content. Lens ATP did not fully recover to control concentrations by 11 days post-injection. A moderate correlation existed between lens weight and total ATP content in control lenses <r=O.509, n=153), but this relationship disappeared with selenite treatment <r=0.023, n=153). There was a significant inhibition by selenite on lens growth from 4 through 11 days after an injection."],"dc:description.degree":["Master of Science"],"dc:format.medium":["BTD"],"dc:format.mimetype":["application/pdf"],"dc:identifier.other":["etd-11142012-040119"],"dc:identifier.uri":["http://hdl.handle.net/10919/45655"],"dc:language.iso":["en"],"dc:publisher":["Virginia Tech"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:title":["The action of selenite on ATP synthesis in rat lens"],"dc:type":["Thesis"],"dc:type.dcmitype":["Text"],"thesis:degree_discipline":["Biochemistry and Nutrition"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Science"],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-24T05:55:57Z"}