{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/44134"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/44134","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"A Forty-Nine Day Evaluation of Bio-Mos® Replacement of Roxarsone in a Commerically Based Broiler Feeding Program","abstract":"A study was conducted to investigate the effects of roxarsone and Bio-Mos® on broiler production, gut morphology and bone strength. Three thousand and ten broilers were randomly assigned to 1 of 5 dietary corn-soybean meal based treatments: 1) negative control (NEG), basal diet; 2) positive control (POS; NEG + 27 ppm Bacitracin MD); 3) roxarsone (ROX; POS + 50 ppm of roxarsone); 4) Bio-Mos® (BIO; POS + 0.15 and 0.5% Bio-Mos® added during the starter and grower periods, respectively); 5) Bio-Mos®+All-Lac XCL (BIO+LAC; POS + 0.2, 0.1, and 0.05% Bio-Mos® during the starter, grower and finishing periods, respectively and 0.25g All-Lac XCL/bird sprayed at hatchery). On day 14, 7 of the 14 replicate pens/treatment were challenged with Eimeria maxima (3 x 104 oocysts/bird). Tibias were collected on day 28 and 49 to determine bone-breaking strength. Non-challenged birds had higher body weight gains (BWG) and lower feed conversion (FCR) from day 0 to 49 than challenged birds (P < 0.05). Jejunal crypt depth was increased in challenged broilers compared to non-challenged broilers at 28 days-of-age (P < 0.05). From day 0 to 35, ROX birds had lower BWG and FI than BIO and BIO+LAC birds (P < 0.05), while FCR was similar. Supplementing roxarsone resulted in reduced feed intake and BWG, but no significant differences were noted in FCR compared to feeding Bio-Mos®. ROX fed broilers had decreased ileal crypt depth compared to all other dietary treatments (P < 0.05). Muscle As concentration was lower than FDA allowable limits in broilers fed ROX without a withdrawal period at 28 days-of-age. Including roxarsone or Bio-Mos® did not generally improve production compared to broilers fed the negative diet.","abstract_html":"A study was conducted to investigate the effects of roxarsone and Bio-Mos® on broiler production, gut morphology and bone strength. Three thousand and ten broilers were randomly assigned to 1 of 5 dietary corn-soybean meal based treatments: 1) negative control (NEG), basal diet; 2) positive control (POS; NEG + 27 ppm Bacitracin MD); 3) roxarsone (ROX; POS + 50 ppm of roxarsone); 4) Bio-Mos® (BIO; POS + 0.15 and 0.5% Bio-Mos® added during the starter and grower periods, respectively); 5) Bio-Mos®+All-Lac XCL (BIO+LAC; POS + 0.2, 0.1, and 0.05% Bio-Mos® during the starter, grower and finishing periods, respectively and 0.25g All-Lac XCL/bird sprayed at hatchery). On day 14, 7 of the 14 replicate pens/treatment were challenged with Eimeria maxima (3 x 104 oocysts/bird). Tibias were collected on day 28 and 49 to determine bone-breaking strength. Non-challenged birds had higher body weight gains (BWG) and lower feed conversion (FCR) from day 0 to 49 than challenged birds (P &lt; 0.05). Jejunal crypt depth was increased in challenged broilers compared to non-challenged broilers at 28 days-of-age (P &lt; 0.05). From day 0 to 35, ROX birds had lower BWG and FI than BIO and BIO+LAC birds (P &lt; 0.05), while FCR was similar. Supplementing roxarsone resulted in reduced feed intake and BWG, but no significant differences were noted in FCR compared to feeding Bio-Mos®. ROX fed broilers had decreased ileal crypt depth compared to all other dietary treatments (P &lt; 0.05). Muscle As concentration was lower than FDA allowable limits in broilers fed ROX without a withdrawal period at 28 days-of-age. Including roxarsone or Bio-Mos® did not generally improve production compared to broilers fed the negative diet.","abstract_has_math":false,"creators":["Herfel, Tina Marie"],"institution":"Virginia Tech","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Animal and Poultry Sciences","degree_department":"Animal and Poultry Sciences","school":null,"contributors":[],"advisors":[],"committee_chairs":["Novak, Curtis L."],"committee_members":["McElroy, Audrey P.","Pierson, Frank William"],"year":2007,"date_issued":"2007-07-23","date_published":"2007-07-23","updated_at":"2026-07-24T05:56:39Z","subjects":["broiler","coccidia","roxarsone","Bio-Mos","Performance"],"languages":[],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-08032007-191149"],"render_values":[{"text":"etd-08032007-191149","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/44134","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["Novak, Curtis L."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["McElroy, Audrey P.","Pierson, Frank William"]},{"key":"dc:contributor.department","label":"Department","values":["Animal and Poultry Sciences"]},{"key":"dc:creator","label":"Author","values":["Herfel, Tina Marie"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-03-14T21:42:07Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-03-14T21:42:07Z","2007-08-28"]},{"key":"dc:date.issued","label":"Date","values":["2007-07-23"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Tech"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Animal and Poultry Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["broiler","coccidia","roxarsone","Bio-Mos","Performance"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-08032007-191149"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/44134"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["A study was conducted to investigate the effects of roxarsone and Bio-Mos® on broiler production, gut morphology and bone strength. Three thousand and ten broilers were randomly assigned to 1 of 5 dietary corn-soybean meal based treatments: 1) negative control (NEG), basal diet; 2) positive control (POS; NEG + 27 ppm Bacitracin MD); 3) roxarsone (ROX; POS + 50 ppm of roxarsone); 4) Bio-Mos® (BIO; POS + 0.15 and 0.5% Bio-Mos® added during the starter and grower periods, respectively); 5) Bio-Mos®+All-Lac XCL (BIO+LAC; POS + 0.2, 0.1, and 0.05% Bio-Mos® during the starter, grower and finishing periods, respectively and 0.25g All-Lac XCL/bird sprayed at hatchery). On day 14, 7 of the 14 replicate pens/treatment were challenged with Eimeria maxima (3 x 104 oocysts/bird). Tibias were collected on day 28 and 49 to determine bone-breaking strength. Non-challenged birds had higher body weight gains (BWG) and lower feed conversion (FCR) from day 0 to 49 than challenged birds (P < 0.05). Jejunal crypt depth was increased in challenged broilers compared to non-challenged broilers at 28 days-of-age (P < 0.05). From day 0 to 35, ROX birds had lower BWG and FI than BIO and BIO+LAC birds (P < 0.05), while FCR was similar. Supplementing roxarsone resulted in reduced feed intake and BWG, but no significant differences were noted in FCR compared to feeding Bio-Mos®. ROX fed broilers had decreased ileal crypt depth compared to all other dietary treatments (P < 0.05). Muscle As concentration was lower than FDA allowable limits in broilers fed ROX without a withdrawal period at 28 days-of-age. Including roxarsone or Bio-Mos® did not generally improve production compared to broilers fed the negative diet."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:title","label":"Title","values":["A Forty-Nine Day Evaluation of Bio-Mos® Replacement of Roxarsone in a Commerically Based Broiler Feeding Program"]}]}],"canonical_facts":{"dc:contributor.committeechair":["Novak, Curtis L."],"dc:contributor.committeemember":["McElroy, Audrey P.","Pierson, Frank William"],"dc:contributor.department":["Animal and Poultry Sciences"],"dc:creator":["Herfel, Tina Marie"],"dc:date.accessioned":["2014-03-14T21:42:07Z"],"dc:date.available":["2014-03-14T21:42:07Z","2007-08-28"],"dc:date.issued":["2007-07-23"],"dc:description.abstract":["A study was conducted to investigate the effects of roxarsone and Bio-Mos® on broiler production, gut morphology and bone strength. Three thousand and ten broilers were randomly assigned to 1 of 5 dietary corn-soybean meal based treatments: 1) negative control (NEG), basal diet; 2) positive control (POS; NEG + 27 ppm Bacitracin MD); 3) roxarsone (ROX; POS + 50 ppm of roxarsone); 4) Bio-Mos® (BIO; POS + 0.15 and 0.5% Bio-Mos® added during the starter and grower periods, respectively); 5) Bio-Mos®+All-Lac XCL (BIO+LAC; POS + 0.2, 0.1, and 0.05% Bio-Mos® during the starter, grower and finishing periods, respectively and 0.25g All-Lac XCL/bird sprayed at hatchery). On day 14, 7 of the 14 replicate pens/treatment were challenged with Eimeria maxima (3 x 104 oocysts/bird). Tibias were collected on day 28 and 49 to determine bone-breaking strength. Non-challenged birds had higher body weight gains (BWG) and lower feed conversion (FCR) from day 0 to 49 than challenged birds (P < 0.05). Jejunal crypt depth was increased in challenged broilers compared to non-challenged broilers at 28 days-of-age (P < 0.05). From day 0 to 35, ROX birds had lower BWG and FI than BIO and BIO+LAC birds (P < 0.05), while FCR was similar. Supplementing roxarsone resulted in reduced feed intake and BWG, but no significant differences were noted in FCR compared to feeding Bio-Mos®. ROX fed broilers had decreased ileal crypt depth compared to all other dietary treatments (P < 0.05). Muscle As concentration was lower than FDA allowable limits in broilers fed ROX without a withdrawal period at 28 days-of-age. Including roxarsone or Bio-Mos® did not generally improve production compared to broilers fed the negative diet."],"dc:description.degree":["Master of Science"],"dc:identifier.other":["etd-08032007-191149"],"dc:identifier.uri":["http://hdl.handle.net/10919/44134"],"dc:publisher":["Virginia Tech"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:subject":["broiler","coccidia","roxarsone","Bio-Mos","Performance"],"dc:title":["A Forty-Nine Day Evaluation of Bio-Mos® Replacement of Roxarsone in a Commerically Based Broiler Feeding Program"],"dc:type":["Thesis"],"thesis:degree_discipline":["Animal and Poultry Sciences"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Science"],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-24T05:56:39Z"}