{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/42851"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/42851","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Gas chromatographic studies of drugs of abuse","abstract":"1. The sensitivity obtained even with the free compounds (except morphine) make gas chromatography a good technique for trace analysis of drugs in biological samples. 2. For many of the drugs studied the detector response curves are not linear with sample concentration but the calibration curves are reproducible if care is exercised. This makes quantitative analysis feasible down to 50-100 nanogram levels with proper technique. 3. Long column life is needed for routine analyses. Those columns employed in this work were used continuously for over seven months with no appreciable deterioration.","abstract_html":"1. The sensitivity obtained even with the free compounds (except morphine) make gas chromatography a good technique for trace analysis of drugs in biological samples. 2. For many of the drugs studied the detector response curves are not linear with sample concentration but the calibration curves are reproducible if care is exercised. This makes quantitative analysis feasible down to 50-100 nanogram levels with proper technique. 3. Long column life is needed for routine analyses. Those columns employed in this work were used continuously for over seven months with no appreciable deterioration.","abstract_has_math":false,"creators":["Hernández, J. Benjamin Esquivel"],"institution":"Virginia Tech","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Chemistry","degree_department":"Chemistry","school":null,"contributors":[],"advisors":[],"committee_chairs":["McNair, Harold M."],"committee_members":["Mason, John G.","Wolfe, James F."],"year":1973,"date_issued":"1973-06-05","date_published":"1973-06-05","updated_at":"2026-07-22T22:19:44Z","subjects":[],"languages":[],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-06032010-020011"],"render_values":[{"text":"etd-06032010-020011","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/42851","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["McNair, Harold M."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Mason, John G.","Wolfe, James F."]},{"key":"dc:contributor.department","label":"Department","values":["Chemistry"]},{"key":"dc:creator","label":"Author","values":["Hernández, J. Benjamin Esquivel"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-03-14T21:36:51Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-03-14T21:36:51Z","2010-06-03"]},{"key":"dc:date.issued","label":"Date","values":["1973-06-05"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Tech"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-06032010-020011"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/42851"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["1. The sensitivity obtained even with the free compounds (except morphine) make gas chromatography a good technique for trace analysis of drugs in biological samples. 2. For many of the drugs studied the detector response curves are not linear with sample concentration but the calibration curves are reproducible if care is exercised. This makes quantitative analysis feasible down to 50-100 nanogram levels with proper technique. 3. Long column life is needed for routine analyses. Those columns employed in this work were used continuously for over seven months with no appreciable deterioration."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["BTD"]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Gas chromatographic studies of drugs of abuse"]}]}],"canonical_facts":{"dc:contributor.committeechair":["McNair, Harold M."],"dc:contributor.committeemember":["Mason, John G.","Wolfe, James F."],"dc:contributor.department":["Chemistry"],"dc:creator":["Hernández, J. Benjamin Esquivel"],"dc:date.accessioned":["2014-03-14T21:36:51Z"],"dc:date.available":["2014-03-14T21:36:51Z","2010-06-03"],"dc:date.issued":["1973-06-05"],"dc:description.abstract":["1. The sensitivity obtained even with the free compounds (except morphine) make gas chromatography a good technique for trace analysis of drugs in biological samples. 2. For many of the drugs studied the detector response curves are not linear with sample concentration but the calibration curves are reproducible if care is exercised. This makes quantitative analysis feasible down to 50-100 nanogram levels with proper technique. 3. Long column life is needed for routine analyses. Those columns employed in this work were used continuously for over seven months with no appreciable deterioration."],"dc:description.degree":["Master of Science"],"dc:format.medium":["BTD"],"dc:format.mimetype":["application/pdf"],"dc:identifier.other":["etd-06032010-020011"],"dc:identifier.uri":["http://hdl.handle.net/10919/42851"],"dc:publisher":["Virginia Tech"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:title":["Gas chromatographic studies of drugs of abuse"],"dc:type":["Thesis"],"dc:type.dcmitype":["Text"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Science"],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-22T22:19:44Z"}