The Asymmetric Synthesis Of The C1'-C10' Portion of Pamamycin-621A

This thesis describes the synthesis of the C1'-C10' portion 72 of the pamamycin-621A using a cuprate conjugate addition to join enone fragment 52 and organostannane fragment 64a. Fragments 52 and 64a were both synthesized from (S)-methylketene dimer 51.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Chemistry

Department dc:contributor.department

Chemistry

Grantor dc:publisher

Virginia Tech

Year dc:date.issued

1998

Author dc:creator

• Bi, Feng

Chair dc:contributor.committeechair

• Calter, Michael A.

Committee members dc:contributor.committeemember

• Tanko, James M.
• Ducker, William A.

• Pamamycin
• Lower Portion
• Synthesis
• Ketene

Statement dc:rights

• In Copyright

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Dc Identifier Other

etd-71498-12035

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/36903