Virginia Tech
Study of Multimode Extrinsic Fabry-Perot Interferometric Fiber Optic Sensor on Biosensing
Abstract
dc:description.abstractThe electrostatic self-assembly (ESA) method presents an effective application in the field of biosensing due to the uniform nanoscale structure. In previous research, a single mode fiber (SMF) sensor system had been investigated for the thin-film measurement due to the high fringe visibility. However, compared with a SMF sensor system, a multimode fiber (MMF) sensor system is lower-cost and has larger sensing area (the fiber core), providing the potential for higher sensing efficiency. In this thesis, a multimode fiber-optic sensor has been developed based on extrinsic Fabry-Perot interferometry (EFPI) for the measurement of optical thickness in self-assembled thin film layers as well as for the immunosensing test. The sensor was fabricated by connecting a multimode fiber (MMF) and a silica wafer. A Fabry-Perot cavity was formed by the reflections from the two interfaces of the wafer. The negatively charged silica wafer could be used as the substrate for the thin film immobilization scheme. The sensor is incorporated into the white-light interferometric system. By monitoring the optical cavity length increment, the self-assembled thin film thickness was measured; the immunoreaction between immunoglobulin G (IgG) and anti-IgG was investigated.
Degree
thesis:*- Name thesis:degree_name
- Master of Science
- Level thesis:degree_level
- masters
- Discipline thesis:degree_discipline
- Electrical and Computer Engineering
- Department dc:contributor.department
- Electrical and Computer Engineering
- Grantor dc:publisher
- Virginia Tech
- Year dc:date.issued
- 2006
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Zhao, Xin
- Chair dc:contributor.committeechair
-
- Wang, Anbo
- Committee members dc:contributor.committeemember
-
- Pickrell, Gary R.
- Cooper, Kristie L.
Subjects
dc:subject × 5Rights
dc:rights- Statement dc:rights
-
- In Copyright
- Licence dc:rights.uri
Identifiers
dc:identifier.*- Dc Identifier Other
- etd-08142006-235542
- OAI identifier oai:identifier
- oai:vtechworks.lib.vt.edu:10919/34534