{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/32959"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/32959","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Development of the Passive Perfusion Probe for Non-Invasive Blood Perfusion Measurement","abstract":"A non-invasive blood perfusion system has been developed and tested in a phantom tissue and an animal model. The system uses a small sensor with a laminated flat thermocouple to measure the heat transfer response to an arbitrary thermal event (convective or conductive) imposed on the tissue surface. Blood perfusion and contact resistance are estimated by comparing heat flux data with a mathematical model of the tissue. The perfusion system was evaluated for repeatability and sensitivity using both a phantom tissue test stand and exposed rat liver tests. Perfusion in the phantom tissue tests was varied by controlling the flow of water into the phantom tissue test section, and the perfusion in the exposed liver tests was varied by temporarily occluding blood flow through the portal vein. The phantom tissue tests indicated that the probe can be used to detect small changes in perfusion (0.009 ml/ml/s). The probe qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein.","abstract_html":"A non-invasive blood perfusion system has been developed and tested in a phantom tissue and an animal model. The system uses a small sensor with a laminated flat thermocouple to measure the heat transfer response to an arbitrary thermal event (convective or conductive) imposed on the tissue surface. Blood perfusion and contact resistance are estimated by comparing heat flux data with a mathematical model of the tissue. The perfusion system was evaluated for repeatability and sensitivity using both a phantom tissue test stand and exposed rat liver tests. Perfusion in the phantom tissue tests was varied by controlling the flow of water into the phantom tissue test section, and the perfusion in the exposed liver tests was varied by temporarily occluding blood flow through the portal vein. The phantom tissue tests indicated that the probe can be used to detect small changes in perfusion (0.009 ml/ml/s). The probe qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein.","abstract_has_math":false,"creators":["Ricketts, Patricia Lynn"],"institution":"Virginia Tech","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Mechanical Engineering","degree_department":"Mechanical Engineering","school":null,"contributors":[],"advisors":[],"committee_chairs":["Diller, Thomas E.","Scott, Elaine P."],"committee_members":["Lanz, Otto I."],"year":2007,"date_issued":"2007-05-03","date_published":"2007-05-03","updated_at":"2026-07-22T22:20:08Z","subjects":["Blood Perfusion","Heat Flux","Phantom Tissue","Parameter Estimation"],"languages":[],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-05182007-144354"],"render_values":[{"text":"etd-05182007-144354","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/32959","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["Diller, Thomas E.","Scott, Elaine P."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Lanz, Otto I."]},{"key":"dc:contributor.department","label":"Department","values":["Mechanical Engineering"]},{"key":"dc:creator","label":"Author","values":["Ricketts, Patricia Lynn"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-03-14T20:37:31Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-03-14T20:37:31Z","2010-10-27"]},{"key":"dc:date.issued","label":"Date","values":["2007-05-03"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Tech"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Mechanical Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Blood Perfusion","Heat Flux","Phantom Tissue","Parameter Estimation"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-05182007-144354"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/32959"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["A non-invasive blood perfusion system has been developed and tested in a phantom tissue and an animal model. 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The probe qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:title","label":"Title","values":["Development of the Passive Perfusion Probe for Non-Invasive Blood Perfusion Measurement"]}]}],"canonical_facts":{"dc:contributor.committeechair":["Diller, Thomas E.","Scott, Elaine P."],"dc:contributor.committeemember":["Lanz, Otto I."],"dc:contributor.department":["Mechanical Engineering"],"dc:creator":["Ricketts, Patricia Lynn"],"dc:date.accessioned":["2014-03-14T20:37:31Z"],"dc:date.available":["2014-03-14T20:37:31Z","2010-10-27"],"dc:date.issued":["2007-05-03"],"dc:description.abstract":["A non-invasive blood perfusion system has been developed and tested in a phantom tissue and an animal model. 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