{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/31906"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/31906","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"A Nondimensional Scaling Parameter for Predicting Pressure Wave Reflection in Stented Arteries","abstract":"Coronary stents have become a very popular treatment for cardiovascular disease, historically the leading cause of death in the United States. Stents, while successful in the short term, are subject to high failure rates (up to 24% in the first six months) due to wall regrowth and clotting, probably due to a combination of abnormal mechanical stresses and disruption of the arterial blood flow. The goal of this research was to develop recommendations concerning ways in which stent design might be improved, focusing on the problem of pressure wave reflections. A one-dimensional finite-difference model was developed to predict these reflections, and effects of variations in stent and vessel properties were examined, including stent stiffness, length, and compliance transition region, as well as vessel radius and wall thickness. The model was solved using a combination of Weighted Essentially Non-Oscillatory (WENO) and Runge-Kutta methods. Over 100 cases were tested. Results showed that reasonable variations in these parameters could induce changes in reflection magnitude of up to ±50%. It was also discovered that the relationship between each of these properties and the resulting wave reflection could be described simply, and the effect of all of them together could in fact be encompassed by a single non-dimensional parameter. This parameter was titled\"Stent Authority,\" and several variations were proposed. It is believed this parameter is a novel way of relating the energy imposed upon the arterial wall by the stent, to the fraction of the incident pressure energy which is reflected from the stented region.","abstract_html":"Coronary stents have become a very popular treatment for cardiovascular disease, historically the leading cause of death in the United States. Stents, while successful in the short term, are subject to high failure rates (up to 24% in the first six months) due to wall regrowth and clotting, probably due to a combination of abnormal mechanical stresses and disruption of the arterial blood flow. The goal of this research was to develop recommendations concerning ways in which stent design might be improved, focusing on the problem of pressure wave reflections. A one-dimensional finite-difference model was developed to predict these reflections, and effects of variations in stent and vessel properties were examined, including stent stiffness, length, and compliance transition region, as well as vessel radius and wall thickness. The model was solved using a combination of Weighted Essentially Non-Oscillatory (WENO) and Runge-Kutta methods. Over 100 cases were tested. Results showed that reasonable variations in these parameters could induce changes in reflection magnitude of up to ±50%. It was also discovered that the relationship between each of these properties and the resulting wave reflection could be described simply, and the effect of all of them together could in fact be encompassed by a single non-dimensional parameter. This parameter was titled"Stent Authority," and several variations were proposed. It is believed this parameter is a novel way of relating the energy imposed upon the arterial wall by the stent, to the fraction of the incident pressure energy which is reflected from the stented region.","abstract_has_math":false,"creators":["Charonko, John James"],"institution":"Virginia Tech","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Engineering Mechanics","degree_department":"Engineering Mechanics","school":null,"contributors":[],"advisors":[],"committee_chairs":["Vlachos, Pavlos P."],"committee_members":["Telionis, Demetri P.","Ragab, Saad A."],"year":2005,"date_issued":"2005-03-17","date_published":"2005-03-17","updated_at":"2026-07-22T22:19:48Z","subjects":["coronary arteries","stents","fluid mechanics","wave reflection","nondimesional parameter","numerical modeling"],"languages":[],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-04252005-115022"],"render_values":[{"text":"etd-04252005-115022","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/31906","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["Vlachos, Pavlos P."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Telionis, Demetri P.","Ragab, Saad A."]},{"key":"dc:contributor.department","label":"Department","values":["Engineering Mechanics"]},{"key":"dc:creator","label":"Author","values":["Charonko, John James"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-03-14T20:34:15Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-03-14T20:34:15Z","2005-05-25"]},{"key":"dc:date.issued","label":"Date","values":["2005-03-17"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Tech"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Engineering Mechanics"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["coronary arteries","stents","fluid mechanics","wave reflection","nondimesional parameter","numerical modeling"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-04252005-115022"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/31906"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Coronary stents have become a very popular treatment for cardiovascular disease, historically the leading cause of death in the United States. Stents, while successful in the short term, are subject to high failure rates (up to 24% in the first six months) due to wall regrowth and clotting, probably due to a combination of abnormal mechanical stresses and disruption of the arterial blood flow. The goal of this research was to develop recommendations concerning ways in which stent design might be improved, focusing on the problem of pressure wave reflections. A one-dimensional finite-difference model was developed to predict these reflections, and effects of variations in stent and vessel properties were examined, including stent stiffness, length, and compliance transition region, as well as vessel radius and wall thickness. The model was solved using a combination of Weighted Essentially Non-Oscillatory (WENO) and Runge-Kutta methods. Over 100 cases were tested. Results showed that reasonable variations in these parameters could induce changes in reflection magnitude of up to ±50%. It was also discovered that the relationship between each of these properties and the resulting wave reflection could be described simply, and the effect of all of them together could in fact be encompassed by a single non-dimensional parameter. This parameter was titled\"Stent Authority,\" and several variations were proposed. It is believed this parameter is a novel way of relating the energy imposed upon the arterial wall by the stent, to the fraction of the incident pressure energy which is reflected from the stented region."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:title","label":"Title","values":["A Nondimensional Scaling Parameter for Predicting Pressure Wave Reflection in Stented Arteries"]}]}],"canonical_facts":{"dc:contributor.committeechair":["Vlachos, Pavlos P."],"dc:contributor.committeemember":["Telionis, Demetri P.","Ragab, Saad A."],"dc:contributor.department":["Engineering Mechanics"],"dc:creator":["Charonko, John James"],"dc:date.accessioned":["2014-03-14T20:34:15Z"],"dc:date.available":["2014-03-14T20:34:15Z","2005-05-25"],"dc:date.issued":["2005-03-17"],"dc:description.abstract":["Coronary stents have become a very popular treatment for cardiovascular disease, historically the leading cause of death in the United States. Stents, while successful in the short term, are subject to high failure rates (up to 24% in the first six months) due to wall regrowth and clotting, probably due to a combination of abnormal mechanical stresses and disruption of the arterial blood flow. The goal of this research was to develop recommendations concerning ways in which stent design might be improved, focusing on the problem of pressure wave reflections. A one-dimensional finite-difference model was developed to predict these reflections, and effects of variations in stent and vessel properties were examined, including stent stiffness, length, and compliance transition region, as well as vessel radius and wall thickness. The model was solved using a combination of Weighted Essentially Non-Oscillatory (WENO) and Runge-Kutta methods. Over 100 cases were tested. Results showed that reasonable variations in these parameters could induce changes in reflection magnitude of up to ±50%. It was also discovered that the relationship between each of these properties and the resulting wave reflection could be described simply, and the effect of all of them together could in fact be encompassed by a single non-dimensional parameter. This parameter was titled\"Stent Authority,\" and several variations were proposed. It is believed this parameter is a novel way of relating the energy imposed upon the arterial wall by the stent, to the fraction of the incident pressure energy which is reflected from the stented region."],"dc:description.degree":["Master of Science"],"dc:identifier.other":["etd-04252005-115022"],"dc:identifier.uri":["http://hdl.handle.net/10919/31906"],"dc:publisher":["Virginia Tech"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:subject":["coronary arteries","stents","fluid mechanics","wave reflection","nondimesional parameter","numerical modeling"],"dc:title":["A Nondimensional Scaling Parameter for Predicting Pressure Wave Reflection in Stented Arteries"],"dc:type":["Thesis"],"thesis:degree_discipline":["Engineering Mechanics"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Science"],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-22T22:19:48Z"}