{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/19254"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/19254","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program","abstract":"Aim: The purpose of this study was to investigate docosahexaenoic acid (DHA) ingestion on muscle damage and inflammation during the first two weeks of a novice resistance training (RT) program. Methods: This study was a placebo-controlled, double-blind design. Forty-one healthy untrained males between the ages of 18 and 28 years consumed 2,000 mg/d of either DHA or corn oil (PCB) for 44 days including a 28 day loading period. Serum fatty acids were analyzed to determine treatment efficacy. During the 17 day training period, an acute eccentric exercise bout was implemented followed by a full-body RT regimen thrice weekly. Six fasted blood draws (days 1, 2, 4, 7, 12, and 17) during this exercise period were analyzed for creatine kinase (CK) and C-reactive protein (CRP). Maximum isometric strength (ISO) of the elbow flexors, delayed onset muscle soreness (DOMS), and range of motion (ROM) were measured on day 1 prior to exercise and also on days 2, 3, 4, 7, 12, and 17. Results: The CK response and the area under the curve (AUC) analysis for DOMS trended to decrease in the DHA group in comparison to placebo (p=0.0925 and p=0.0536, respectively). Treatment showed no effect on CRP levels. DHA supplementation significantly increased serum DHA by 380% as a proportion of total fatty acids (p<0.0001). Conclusion: This study does not demonstrate convincing benefits of DHA ingestion to recovery from a new resistance exercise program but does suggest a need for further investigation.","abstract_html":"Aim: The purpose of this study was to investigate docosahexaenoic acid (DHA) ingestion on muscle damage and inflammation during the first two weeks of a novice resistance training (RT) program. Methods: This study was a placebo-controlled, double-blind design. Forty-one healthy untrained males between the ages of 18 and 28 years consumed 2,000 mg/d of either DHA or corn oil (PCB) for 44 days including a 28 day loading period. Serum fatty acids were analyzed to determine treatment efficacy. During the 17 day training period, an acute eccentric exercise bout was implemented followed by a full-body RT regimen thrice weekly. Six fasted blood draws (days 1, 2, 4, 7, 12, and 17) during this exercise period were analyzed for creatine kinase (CK) and C-reactive protein (CRP). Maximum isometric strength (ISO) of the elbow flexors, delayed onset muscle soreness (DOMS), and range of motion (ROM) were measured on day 1 prior to exercise and also on days 2, 3, 4, 7, 12, and 17. Results: The CK response and the area under the curve (AUC) analysis for DOMS trended to decrease in the DHA group in comparison to placebo (p=0.0925 and p=0.0536, respectively). Treatment showed no effect on CRP levels. DHA supplementation significantly increased serum DHA by 380% as a proportion of total fatty acids (p&lt;0.0001). Conclusion: This study does not demonstrate convincing benefits of DHA ingestion to recovery from a new resistance exercise program but does suggest a need for further investigation.","abstract_has_math":false,"creators":["Drager, Christopher John"],"institution":"Virginia Tech","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Human Nutrition, Foods, and Exercise","degree_department":"Human Nutrition, Foods, and Exercise","school":null,"contributors":[],"advisors":[],"committee_chairs":["Rankin, Janet L. Walberg"],"committee_members":["Newton, William E.","Williams, Jay H."],"year":2013,"date_issued":"2013-01-17","date_published":"2013-01-17","updated_at":"2026-07-22T22:19:49Z","subjects":["Omega-3 fatty acids","strength training","creatine kinase","C-reactive protein"],"languages":[],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["vt_gsexam:176"],"render_values":[{"text":"vt_gsexam:176","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/19254","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["Rankin, Janet L. 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Methods: This study was a placebo-controlled, double-blind design. Forty-one healthy untrained males between the ages of 18 and 28 years consumed 2,000 mg/d of either DHA or corn oil (PCB) for 44 days including a 28 day loading period. Serum fatty acids were analyzed to determine treatment efficacy. During the 17 day training period, an acute eccentric exercise bout was implemented followed by a full-body RT regimen thrice weekly. Six fasted blood draws (days 1, 2, 4, 7, 12, and 17) during this exercise period were analyzed for creatine kinase (CK) and C-reactive protein (CRP). Maximum isometric strength (ISO) of the elbow flexors, delayed onset muscle soreness (DOMS), and range of motion (ROM) were measured on day 1 prior to exercise and also on days 2, 3, 4, 7, 12, and 17. Results: The CK response and the area under the curve (AUC) analysis for DOMS trended to decrease in the DHA group in comparison to placebo (p=0.0925 and p=0.0536, respectively). Treatment showed no effect on CRP levels. DHA supplementation significantly increased serum DHA by 380% as a proportion of total fatty acids (p<0.0001). Conclusion: This study does not demonstrate convincing benefits of DHA ingestion to recovery from a new resistance exercise program but does suggest a need for further investigation."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Master of Science"]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["ETD"]},{"key":"dc:title","label":"Title","values":["Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program"]}]}],"canonical_facts":{"dc:contributor.committeechair":["Rankin, Janet L. Walberg"],"dc:contributor.committeemember":["Newton, William E.","Williams, Jay H."],"dc:contributor.department":["Human Nutrition, Foods, and Exercise"],"dc:creator":["Drager, Christopher John"],"dc:date.accessioned":["2013-02-19T22:40:58Z"],"dc:date.available":["2013-02-19T22:40:58Z"],"dc:date.issued":["2013-01-17"],"dc:description.abstract":["Aim: The purpose of this study was to investigate docosahexaenoic acid (DHA) ingestion on muscle damage and inflammation during the first two weeks of a novice resistance training (RT) program. Methods: This study was a placebo-controlled, double-blind design. Forty-one healthy untrained males between the ages of 18 and 28 years consumed 2,000 mg/d of either DHA or corn oil (PCB) for 44 days including a 28 day loading period. Serum fatty acids were analyzed to determine treatment efficacy. During the 17 day training period, an acute eccentric exercise bout was implemented followed by a full-body RT regimen thrice weekly. Six fasted blood draws (days 1, 2, 4, 7, 12, and 17) during this exercise period were analyzed for creatine kinase (CK) and C-reactive protein (CRP). Maximum isometric strength (ISO) of the elbow flexors, delayed onset muscle soreness (DOMS), and range of motion (ROM) were measured on day 1 prior to exercise and also on days 2, 3, 4, 7, 12, and 17. Results: The CK response and the area under the curve (AUC) analysis for DOMS trended to decrease in the DHA group in comparison to placebo (p=0.0925 and p=0.0536, respectively). Treatment showed no effect on CRP levels. DHA supplementation significantly increased serum DHA by 380% as a proportion of total fatty acids (p<0.0001). Conclusion: This study does not demonstrate convincing benefits of DHA ingestion to recovery from a new resistance exercise program but does suggest a need for further investigation."],"dc:description.degree":["Master of Science"],"dc:format.medium":["ETD"],"dc:identifier.other":["vt_gsexam:176"],"dc:identifier.uri":["http://hdl.handle.net/10919/19254"],"dc:publisher":["Virginia Tech"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:subject":["Omega-3 fatty acids","strength training","creatine kinase","C-reactive protein"],"dc:title":["Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program"],"dc:type":["Thesis"],"thesis:degree_discipline":["Human Nutrition, Foods, and Exercise"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Science"],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-22T22:19:49Z"}