Abstract
dc:description.abstractThis thesis provides insight into methods for estimating blood perfusion, emphasizing the need for accurate modeling in dynamic physiological environments. The thesis critically examines conventional error function solutions used in steady state or gradually changing blood flow scenarios, revealing their shortcomings in accurately reflecting more rapid changes in blood perfusion. To address this limitation, this study introduces a novel prediction model based on the finite-difference method (FDM) specifically designed to produce accurate results under different blood flow perfusion conditions. A comparative analysis concludes that the FDM-based model is consistent with traditional error function methods under constant blood perfusion conditions, thus establishing its validity under dynamic and steady blood flow conditions. In addition, the study attempts to determine whether analytical solutions exist that are suitable for changing perfusion conditions. Three alternative analytical estimation methods were explored, each exposing the common thread of inadequate responsiveness to sudden changes in blood perfusion. Based on the advantages and disadvantages of the error function and FDM estimation, a combination of these two methods was developed. Utilizing the simplicity and efficiency of the error function, the prediction of contact resistance and core temperature along with the initial blood perfusion was first made at the beginning of the data. Then the subsequent blood perfusion values were predicted using the FDM, as the FDM can effectively respond to changing blood perfusion values.
Degree
thesis:*- Name thesis:degree_name
- Master of Science
- Level thesis:degree_level
- masters
- Discipline thesis:degree_discipline
- Mechanical Engineering
- Department dc:contributor.department
- Mechanical Engineering
- Grantor dc:publisher
- Virginia Tech
- Year dc:date.issued
- 2023
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Sheng, Baoyi
- Chairs dc:contributor.committeechair
-
- Huxtable, Scott T.
- Diller, Thomas E.
- Committee member dc:contributor.committeemember
-
- Paul, Mark R.
Subjects
dc:subject × 3Rights
dc:rights- Statement dc:rights
-
- In Copyright
- Licence dc:rights.uri
- Language dc:language.iso
- en
Identifiers
dc:identifier.*- Dc Identifier Other
- vt_gsexam:39415
- OAI identifier oai:identifier
- oai:vtechworks.lib.vt.edu:10919/117272