Parkinson's Disease Automated Hand Tremor Analysis from Spiral Images

Parkinson’s Disease is a neurological degenerative disease affecting more than six million people worldwide. It is a progressive disease, impacting a person’s movements and thought processes. In recent years, computer vision and machine learning researchers have been developing techniques to aid in the diagnosis. This thesis is motivated by the exploration of hand tremor symptoms in Parkinson’s patients from the Archimedean Spiral test, a paper-and-pencil test used to evaluate hand tremors. This work presents a novel Fourier Domain analysis technique that transforms the pencil content of hand-drawn spiral images into frequency features. Our technique is applied to an image dataset consisting of spirals drawn by healthy individuals and people with Parkinson’s Disease. The Fourier Domain analysis technique achieves 81.5% accuracy predicting images drawn by someone with Parkinson’s, a result 6% higher than previous methods. We compared this method against the results using extracted features from the ResNet-50 and VGG16 pre-trained deep network models. The VGG16 extracted features achieve 95.4% accuracy classifying images drawn by people with Parkinson’s Disease. The extracted features of both methods were also used to develop a tremor severity rating system which scores the spiral images on a scale from 0 (no tremor) to 1 (severe tremor). The results show correlation to the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) developed by the International Parkinson and Movement Disorder Society. These results can be useful for aiding in early detection of tremors, the medical treatment process, and symptom tracking to monitor the progression of Parkinson’s Disease.

Name thesis:degree_name

M.S.

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Computer Engineering

Department dc:contributor.department

Electrical and Computer Engineering

Grantor dc:publisher

Virginia Tech

Year dc:date.issued

2023

Author dc:creator

• DeSipio, Rebecca E.

Chair dc:contributor.committeechair

• Abbott, A. Lynn

Committee members dc:contributor.committeemember

• Buehrer, Michael
• Jia, Ruoxi

• Archimedean Spiral
• Machine Learning
• Deep Learning
• Image Classification
• Fourier Domain

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10919/115350

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/115350