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Virginia Polytechnic Institute and State University

Biochemical detection of smoking exposure of cardiac outpatients

Abstract

dc:description.abstract

Thirty-seven outpatients (M=34, F=3) undergoing rehabilitative exercise in two community-based programs were evaluated for smoking behavior using three separate measures. The specific objective of the study, i.e., to compare concurrent measures of smoking exposure via end-tidal carbon monoxide (F<sub>ET<sub>CO</sub></sub> ), saliva thiocyanate (SCN) and questionnaire responses, were initially concealed from the subjects to avoid experimental bias that might alter smoking behavior or questionnaire responses. Questions on smoking status and topography were intermingled with a variety of other coronary risk items to further mask the objectives. Triangulation of data for the F<sub>ET<sub>CO</sub></sub> and SCN responses and the smoking admission/denial item on the questionnaire, led to acceptance of biochemical thresholds for smoking detection (F<sub>ET<sub>CO</sub></sub> =9ppm, SCN=55 umol•1<sup>-1</sup> ). Twelve subjects (32%) evidenced F<sub>ET<sub>CO</sub></sub> levels high enough to be designated as smokers (9-37 ppm) and each was an admitted smoker. Of the 12 admitted smokers, 11 demonstrated SCN levels between 58-278 umol•1<sup>-1</sup>. Among the 25 who denied smoking, only 3 patients revealed SCN levels higher than 55 umol/1<sup>-1</sup>. Multiple linear regression analyses showed that responses to a few smoking topographic items among the admitted smokers explained much of the variance in biochemical exposure (71-87%). These results show the efficacy of smoking status and topography questionnaire items for identification of current smokers and determination of those who have an increased coronary risk factor.

Degree

thesis:*
Name thesis:degree_name
M.S.
Level thesis:degree_level
masters
Discipline thesis:degree_discipline
Education
Department dc:contributor.department
Education
Grantor dc:publisher
Virginia Polytechnic Institute and State University
Year dc:date.issued
1983

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Hankla, Donna Sturgill

Rights

dc:rights
Statement dc:rights
  • In Copyright
Language dc:language.iso
en

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/10919/114413
OAI identifier oai:identifier
oai:vtechworks.lib.vt.edu:10919/114413

Chain of custody

source
Harvested from
Virginia Tech
Base URL
vtechworks.lib.vt.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
related terms
citation

Hankla, Donna Sturgill. Biochemical detection of smoking exposure of cardiac outpatients. masters thesis, Virginia Polytechnic Institute and State University, 1983. http://hdl.handle.net/10919/114413