A multiwavelength detector and hydrodynamic chromatography system for the determination of particle size and size distribution

The knowledge of particle size and size distribution are important parameters for understanding the behavior of numerous colloid systems. These areas include for example, clays, viruses, paints and blood. Until recently this information could be obtained only by the use of expensive, slow and complex instrumentation. Hydrodynamic chromatography provides a means of investigating particles in the submicron and micron region. The separation mechanism of this method is based upon the flow parameters with which the solute particles interact as they pass through a packed column. In the past the interpretation of these chromatograms has been based upon the mathematical modeling of the column parameters. We have developed a new multiwavelength detector system to be used in conjunction with hydrodynamic chromatography which provides size and concentration information of the eluant directly. The result is a rugged system that provides size and size distribution information rapidly and at low cost.

Name thesis:degree_name

Ph. D.

Level thesis:degree_level

doctoral

Discipline thesis:degree_discipline

Chemistry

Department dc:contributor.department

Chemistry

Grantor dc:publisher

Virginia Polytechnic Institute and State University

Year dc:date.issued

1983

Author dc:creator

• Knipe, Charles Robert

Statement dc:rights

• In Copyright

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10919/110290

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/110290