{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/106063"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/106063","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Retention trends of chemical classes using CCl₄ as a carrier solvent in normal-phase HPLC","abstract":"Carbon tetrachloride (CCl₄ ) was closely evaluated as a carrier solvent in high-performance liquid chromatography (HPLC). The separation and retention trends of ninety-two selected compounds from eleven chemical classes (furans, thiophenes, aromatic hydrocarbons, ethers, esters, ketones, aldehydes, aromatic amines, azaarenes, alcohols and phenols) on three analytical silica-bonded phase (amino (NH₂), cyano (CN) and polar amino-cyano (PAC)) columns were investigated with CCl₄ and refractive index (RI) detection. The sample capacity and column efficiency of each of the NH₂ and PAC columns were measured and compared. Besides, a method of determining unmeasurable capacity factors (k' values) was found and illustrated.","abstract_html":"Carbon tetrachloride (CCl₄ ) was closely evaluated as a carrier solvent in high-performance liquid chromatography (HPLC). The separation and retention trends of ninety-two selected compounds from eleven chemical classes (furans, thiophenes, aromatic hydrocarbons, ethers, esters, ketones, aldehydes, aromatic amines, azaarenes, alcohols and phenols) on three analytical silica-bonded phase (amino (NH₂), cyano (CN) and polar amino-cyano (PAC)) columns were investigated with CCl₄ and refractive index (RI) detection. The sample capacity and column efficiency of each of the NH₂ and PAC columns were measured and compared. Besides, a method of determining unmeasurable capacity factors (k' values) was found and illustrated.","abstract_has_math":false,"creators":["Wang, Muh S."],"institution":"Virginia Polytechnic Institute and State University","degree_name":"M.S.","degree_level":"masters","degree_discipline":"Chemistry","degree_department":"Chemistry","school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1985,"date_issued":"1985","date_published":"1985","updated_at":"2026-07-22T22:19:41Z","subjects":[],"languages":["en"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10919/106063","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.department","label":"Department","values":["Chemistry"]},{"key":"dc:creator","label":"Author","values":["Wang, Muh S."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2021-10-26T20:09:59Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2021-10-26T20:09:59Z"]},{"key":"dc:date.issued","label":"Date","values":["1985"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Polytechnic Institute and State University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/106063"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Carbon tetrachloride (CCl₄ ) was closely evaluated as a carrier solvent in high-performance liquid chromatography (HPLC). The separation and retention trends of ninety-two selected compounds from eleven chemical classes (furans, thiophenes, aromatic hydrocarbons, ethers, esters, ketones, aldehydes, aromatic amines, azaarenes, alcohols and phenols) on three analytical silica-bonded phase (amino (NH₂), cyano (CN) and polar amino-cyano (PAC)) columns were investigated with CCl₄ and refractive index (RI) detection. The sample capacity and column efficiency of each of the NH₂ and PAC columns were measured and compared. Besides, a method of determining unmeasurable capacity factors (k' values) was found and illustrated."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["M.S."]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Retention trends of chemical classes using CCl₄ as a carrier solvent in normal-phase HPLC"]}]}],"canonical_facts":{"dc:contributor.department":["Chemistry"],"dc:creator":["Wang, Muh S."],"dc:date.accessioned":["2021-10-26T20:09:59Z"],"dc:date.available":["2021-10-26T20:09:59Z"],"dc:date.issued":["1985"],"dc:description.abstract":["Carbon tetrachloride (CCl₄ ) was closely evaluated as a carrier solvent in high-performance liquid chromatography (HPLC). The separation and retention trends of ninety-two selected compounds from eleven chemical classes (furans, thiophenes, aromatic hydrocarbons, ethers, esters, ketones, aldehydes, aromatic amines, azaarenes, alcohols and phenols) on three analytical silica-bonded phase (amino (NH₂), cyano (CN) and polar amino-cyano (PAC)) columns were investigated with CCl₄ and refractive index (RI) detection. The sample capacity and column efficiency of each of the NH₂ and PAC columns were measured and compared. Besides, a method of determining unmeasurable capacity factors (k' values) was found and illustrated."],"dc:description.degree":["M.S."],"dc:format.mimetype":["application/pdf"],"dc:identifier.uri":["http://hdl.handle.net/10919/106063"],"dc:language.iso":["en"],"dc:publisher":["Virginia Polytechnic Institute and State University"],"dc:rights":["In Copyright"],"dc:rights.uri":["http://rightsstatements.org/vocab/InC/1.0/"],"dc:title":["Retention trends of chemical classes using CCl₄ as a carrier solvent in normal-phase HPLC"],"dc:type":["Thesis"],"dc:type.dcmitype":["Text"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["masters"],"thesis:degree_name":["M.S."],"thesis:institution_name":["Virginia Polytechnic Institute and State University"]},"updated_at":"2026-07-22T22:19:41Z"}