{"id":{"repo_id":"vilnius","oai_identifier":"oai:vu.lt:elaba:210578007"},"canonical_url":"https://search.dev.ndltd.org/etd/vilnius/oai:vu.lt:elaba:210578007","repository":{"repo_id":"vilnius","name":"Vilnius University","base_url":"https://epublications.vu.lt/oai"},"display":{"title":"Bioaktyviųjų joninių skysčių aukštosios skyros BMR tyrimas /","abstract":"Bioactive room temperature ionic liquids (b-RTIL) are getting more popular in the field of ionic liquids. The ionic liquids are composed of organic cation molecules and organic or inorganic molecule anions. IL have low melting temperature; low vapour pressure and their chemical structure can be altered. b-RTILs are different from the regular IL since b-RTILs are compatible with the human organism. That means, that b-RTIL can be used in medicine by increasing drug solubility in water. NMR spectroscopy is used to analyse b-RTILs – choline lysinate, choline tryptophanate and choline glycinate ([Ch][Lys], [Ch][Trp] and [Ch][Gly]). Also, with NMR we can analyse [Ch][Lys] interaction with water molecules by measuring the chemical shift of both water molecule and [Ch][Lys] protons at the b-RTIL concentration between 10-5 and 1 molar fraction. [Ch][Lys] cation protons’ chemical shifts reach the plateau at χ_RTIL=10^(-4). molar fraction. The chemical shifts of [Lys] anion protons do not reach the plateau at the measured concentration interval. Water molecule chemical shift plateaus at χ_RTIL=1,5×10^(-2) molar fraction. In [Ch][Trp] water mixture, all molecules chemical shift plateaus at χ_RTIL=10^(-4) molar fraction. In [Ch][Gly] cation protons chemical shift stabilizes at a concentration of χ_RTIL=〖4×10〗^(-4) molar fraction while anion proton chemical shift stabilizes at 〖2,5×10〗^(-5) molar fraction. Water chemical shift plateaus at a concentration of 2×10^(-5) molar fraction.","abstract_html":"Bioactive room temperature ionic liquids (b-RTIL) are getting more popular in the field of ionic liquids. The ionic liquids are composed of organic cation molecules and organic or inorganic molecule anions. IL have low melting temperature; low vapour pressure and their chemical structure can be altered. b-RTILs are different from the regular IL since b-RTILs are compatible with the human organism. That means, that b-RTIL can be used in medicine by increasing drug solubility in water. NMR spectroscopy is used to analyse b-RTILs – choline lysinate, choline tryptophanate and choline glycinate ([Ch][Lys], [Ch][Trp] and [Ch][Gly]). Also, with NMR we can analyse [Ch][Lys] interaction with water molecules by measuring the chemical shift of both water molecule and [Ch][Lys] protons at the b-RTIL concentration between 10-5 and 1 molar fraction. [Ch][Lys] cation protons’ chemical shifts reach the plateau at χ_RTIL=10^(-4). molar fraction. The chemical shifts of [Lys] anion protons do not reach the plateau at the measured concentration interval. Water molecule chemical shift plateaus at χ_RTIL=1,5×10^(-2) molar fraction. In [Ch][Trp] water mixture, all molecules chemical shift plateaus at χ_RTIL=10^(-4) molar fraction. In [Ch][Gly] cation protons chemical shift stabilizes at a concentration of χ_RTIL=〖4×10〗^(-4) molar fraction while anion proton chemical shift stabilizes at 〖2,5×10〗^(-5) molar fraction. Water chemical shift plateaus at a concentration of 2×10^(-5) molar fraction.","abstract_has_math":false,"creators":["Mikalauskas, Lukas,"],"institution":"Institutional Repository of Vilnius University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024","date_published":"2024","updated_at":"2026-07-24T05:55:44Z","subjects":[],"languages":["lit"],"rights":["info:eu-repo/semantics/openAccess"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://repository.vu.lt/VU:ELABAETD210578007&prefLang=en_US","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Mikalauskas, Lukas,"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2024"]},{"key":"dc:publisher","label":"Institution","values":["Institutional Repository of Vilnius University"]},{"key":"dc:relation","label":"Dc Relation","values":["https://epublications.vu.lt/object/elaba:210578007/210578007.pdf"]},{"key":"dc:type","label":"Dc Type","values":["info:eu-repo/semantics/bachelorThesis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["lit"]},{"key":"dc:rights","label":"Dc Rights","values":["info:eu-repo/semantics/openAccess"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://repository.vu.lt/VU:ELABAETD210578007&prefLang=en_US"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Bioactive room temperature ionic liquids (b-RTIL) are getting more popular in the field of ionic liquids. The ionic liquids are composed of organic cation molecules and organic or inorganic molecule anions. IL have low melting temperature; low vapour pressure and their chemical structure can be altered. b-RTILs are different from the regular IL since b-RTILs are compatible with the human organism. That means, that b-RTIL can be used in medicine by increasing drug solubility in water. NMR spectroscopy is used to analyse b-RTILs – choline lysinate, choline tryptophanate and choline glycinate ([Ch][Lys], [Ch][Trp] and [Ch][Gly]). Also, with NMR we can analyse [Ch][Lys] interaction with water molecules by measuring the chemical shift of both water molecule and [Ch][Lys] protons at the b-RTIL concentration between 10-5 and 1 molar fraction. [Ch][Lys] cation protons’ chemical shifts reach the plateau at χ_RTIL=10^(-4). molar fraction. The chemical shifts of [Lys] anion protons do not reach the plateau at the measured concentration interval. Water molecule chemical shift plateaus at χ_RTIL=1,5×10^(-2) molar fraction. In [Ch][Trp] water mixture, all molecules chemical shift plateaus at χ_RTIL=10^(-4) molar fraction. In [Ch][Gly] cation protons chemical shift stabilizes at a concentration of χ_RTIL=〖4×10〗^(-4) molar fraction while anion proton chemical shift stabilizes at 〖2,5×10〗^(-5) molar fraction. Water chemical shift plateaus at a concentration of 2×10^(-5) molar fraction."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Bioaktyviųjų joninių skysčių aukštosios skyros BMR tyrimas /","High resolution nmr study of bioactive ionic liquids."]}]}],"canonical_facts":{"dc:creator":["Mikalauskas, Lukas,"],"dc:date":["2024"],"dc:description":["Bioactive room temperature ionic liquids (b-RTIL) are getting more popular in the field of ionic liquids. The ionic liquids are composed of organic cation molecules and organic or inorganic molecule anions. IL have low melting temperature; low vapour pressure and their chemical structure can be altered. b-RTILs are different from the regular IL since b-RTILs are compatible with the human organism. That means, that b-RTIL can be used in medicine by increasing drug solubility in water. NMR spectroscopy is used to analyse b-RTILs – choline lysinate, choline tryptophanate and choline glycinate ([Ch][Lys], [Ch][Trp] and [Ch][Gly]). Also, with NMR we can analyse [Ch][Lys] interaction with water molecules by measuring the chemical shift of both water molecule and [Ch][Lys] protons at the b-RTIL concentration between 10-5 and 1 molar fraction. [Ch][Lys] cation protons’ chemical shifts reach the plateau at χ_RTIL=10^(-4). molar fraction. The chemical shifts of [Lys] anion protons do not reach the plateau at the measured concentration interval. Water molecule chemical shift plateaus at χ_RTIL=1,5×10^(-2) molar fraction. In [Ch][Trp] water mixture, all molecules chemical shift plateaus at χ_RTIL=10^(-4) molar fraction. In [Ch][Gly] cation protons chemical shift stabilizes at a concentration of χ_RTIL=〖4×10〗^(-4) molar fraction while anion proton chemical shift stabilizes at 〖2,5×10〗^(-5) molar fraction. Water chemical shift plateaus at a concentration of 2×10^(-5) molar fraction."],"dc:format":["application/pdf"],"dc:identifier":["https://repository.vu.lt/VU:ELABAETD210578007&prefLang=en_US"],"dc:language":["lit"],"dc:publisher":["Institutional Repository of Vilnius University"],"dc:relation":["https://epublications.vu.lt/object/elaba:210578007/210578007.pdf"],"dc:rights":["info:eu-repo/semantics/openAccess"],"dc:title":["Bioaktyviųjų joninių skysčių aukštosios skyros BMR tyrimas /","High resolution nmr study of bioactive ionic liquids."],"dc:type":["info:eu-repo/semantics/bachelorThesis"]},"updated_at":"2026-07-24T05:55:44Z"}