{"id":{"repo_id":"vcu","oai_identifier":"oai:scholarscompass.vcu.edu:etd-2153"},"canonical_url":"https://search.dev.ndltd.org/etd/vcu/oai:scholarscompass.vcu.edu:etd-2153","repository":{"repo_id":"vcu","name":"Virginia Commonwealth University","base_url":"https://scholarscompass.vcu.edu/do/oai/"},"display":{"title":"Changes in Serum Osmolality and the Clinical Manifestations of the Dialysis Disequilibrium Syndrome","abstract":"The purpose of this study was to determine if a relationship existed between the change in serum osmolality in the chronic renal failure patient on hemodialysis and the number of clinical symptoms of the dialysis disequilibrium syndrome experienced during hemodialysis. The study was conducted at the Renal Dialysis Unit of an urban medical center located in a southeastern city. Data were collected from May 25, 1978 to June 30, 1978. Data were obtained during 28 hemodialysis procedures performed on 11 subjects. Serum osmolality measurements were collected prior to initiation of the dialysis procedure, at half-hour intervals during dialysis, and prior to termination of dialysis. Clinical symptoms which occurred during dialysis were recorded by the patients and nursing personnel. The hypothesis was that the number of clinical symptoms of the dialysis disequilibrium syndrome experienced by the chronic renal failure patient during hemodialysis will increase as the serum osmolality decreases.","abstract_html":"The purpose of this study was to determine if a relationship existed between the change in serum osmolality in the chronic renal failure patient on hemodialysis and the number of clinical symptoms of the dialysis disequilibrium syndrome experienced during hemodialysis. The study was conducted at the Renal Dialysis Unit of an urban medical center located in a southeastern city. Data were collected from May 25, 1978 to June 30, 1978. Data were obtained during 28 hemodialysis procedures performed on 11 subjects. Serum osmolality measurements were collected prior to initiation of the dialysis procedure, at half-hour intervals during dialysis, and prior to termination of dialysis. Clinical symptoms which occurred during dialysis were recorded by the patients and nursing personnel. The hypothesis was that the number of clinical symptoms of the dialysis disequilibrium syndrome experienced by the chronic renal failure patient during hemodialysis will increase as the serum osmolality decreases.","abstract_has_math":false,"creators":["Young, Donna L."],"institution":null,"degree_name":"Master of Science","degree_level":"Thesis","degree_discipline":"Adult Health Nursing","degree_department":null,"school":null,"contributors":["Dr. Jeanette B. Kissinger"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1978,"date_issued":"1978-01-01T08:00:00Z","date_published":"1978-01-01T08:00:00Z","updated_at":"2026-07-24T05:54:53Z","subjects":["kidney failure","dialysis","hypertonic solution","Medicine and Health Sciences","Nursing"],"languages":[],"rights":["© The Author"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarscompass.vcu.edu/etd/1154"],"render_values":[{"text":"https://scholarscompass.vcu.edu/etd/1154","href":"https://scholarscompass.vcu.edu/etd/1154","code":true}]}]},"links":{"outbound_url":"https://doi.org/10.25772/3RE7-QQ36","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Dr. Jeanette B. 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The study was conducted at the Renal Dialysis Unit of an urban medical center located in a southeastern city. Data were collected from May 25, 1978 to June 30, 1978. Data were obtained during 28 hemodialysis procedures performed on 11 subjects. Serum osmolality measurements were collected prior to initiation of the dialysis procedure, at half-hour intervals during dialysis, and prior to termination of dialysis. Clinical symptoms which occurred during dialysis were recorded by the patients and nursing personnel. The hypothesis was that the number of clinical symptoms of the dialysis disequilibrium syndrome experienced by the chronic renal failure patient during hemodialysis will increase as the serum osmolality decreases."]},{"key":"dc:title","label":"Title","values":["Changes in Serum Osmolality and the Clinical Manifestations of the Dialysis Disequilibrium Syndrome"]}]}],"canonical_facts":{"dc:contributor":["Dr. Jeanette B. Kissinger"],"dc:creator":["Young, Donna L."],"dc:date.available":["2014-07-09T07:00:00Z"],"dc:description.abstract":["The purpose of this study was to determine if a relationship existed between the change in serum osmolality in the chronic renal failure patient on hemodialysis and the number of clinical symptoms of the dialysis disequilibrium syndrome experienced during hemodialysis. The study was conducted at the Renal Dialysis Unit of an urban medical center located in a southeastern city. Data were collected from May 25, 1978 to June 30, 1978. Data were obtained during 28 hemodialysis procedures performed on 11 subjects. Serum osmolality measurements were collected prior to initiation of the dialysis procedure, at half-hour intervals during dialysis, and prior to termination of dialysis. Clinical symptoms which occurred during dialysis were recorded by the patients and nursing personnel. The hypothesis was that the number of clinical symptoms of the dialysis disequilibrium syndrome experienced by the chronic renal failure patient during hemodialysis will increase as the serum osmolality decreases."],"dc:identifier":["https://doi.org/10.25772/3RE7-QQ36","https://scholarscompass.vcu.edu/etd/1154"],"dc:rights":["© The Author"],"dc:subject":["kidney failure","dialysis","hypertonic solution","Medicine and Health Sciences","Nursing"],"dc:title":["Changes in Serum Osmolality and the Clinical Manifestations of the Dialysis Disequilibrium Syndrome"],"thesis:degree_discipline":["Adult Health Nursing"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science"]},"updated_at":"2026-07-24T05:54:53Z"}