{"id":{"repo_id":"varna","oai_identifier":"oai:repository.mu-varna.bg:nls/4231"},"canonical_url":"https://search.dev.ndltd.org/etd/varna/oai:repository.mu-varna.bg:nls/4231","repository":{"repo_id":"varna","name":"Medical University of Varna","base_url":"https://repository.mu-varna.bg/oai/request"},"display":{"title":"Analysis and Assessment of Psychological Factors in Patients with Chronic Kidney Disease in the Pre-Dialysis and Dialysis Stages // Анализ и оценка на психологичните фактори при пациенти с хронично бъбречно заболяване в преддиализен и диализен стадий","abstract":"The thesis aims to assess the role of psychological factors—stress, depressive experiences, and social support—in patients with chronic kidney disease (CKD) in both pre-dialysis and dialysis stages. The cohort includes 60 patients undergoing hemodialysis (HD) treatment in stage G5 and 30 patients diagnosed with CKD in stages G1–G4. The results indicate higher levels of stress and depressive experiences among dialysis-dependent patients compared to those in the pre-dialysis stage. Patients with CKD (G1–G4) exhibit significantly higher levels of social support indicators compared to the HD group. Correlation analysis reveals a statistically significant relationship between all listed manifestations of stress among patients in the end stage of CKD. A stronger positive correlation is observed among all indicators of social support in patients diagnosed with CKD. Regression analysis does not reveal statistically significant results regarding subjectively perceived psychological factors in relation to survival among dialysis-dependent patients. Only higher levels of anxiety are associated with reduced survival in this group. The findings support the need for implementing targeted activities and comprehensive educational programs aimed at preventing the development of psychological conditions that affect the psycho-emotional status of patients diagnosed with CKD, particularly at the initiation of HD treatment.","abstract_html":"The thesis aims to assess the role of psychological factors—stress, depressive experiences, and social support—in patients with chronic kidney disease (CKD) in both pre-dialysis and dialysis stages. The cohort includes 60 patients undergoing hemodialysis (HD) treatment in stage G5 and 30 patients diagnosed with CKD in stages G1–G4. The results indicate higher levels of stress and depressive experiences among dialysis-dependent patients compared to those in the pre-dialysis stage. Patients with CKD (G1–G4) exhibit significantly higher levels of social support indicators compared to the HD group. Correlation analysis reveals a statistically significant relationship between all listed manifestations of stress among patients in the end stage of CKD. A stronger positive correlation is observed among all indicators of social support in patients diagnosed with CKD. Regression analysis does not reveal statistically significant results regarding subjectively perceived psychological factors in relation to survival among dialysis-dependent patients. Only higher levels of anxiety are associated with reduced survival in this group. The findings support the need for implementing targeted activities and comprehensive educational programs aimed at preventing the development of psychological conditions that affect the psycho-emotional status of patients diagnosed with CKD, particularly at the initiation of HD treatment.","abstract_has_math":false,"creators":["Stavreva, Aleksandra","Ставрева, Александра"],"institution":"Medical University of Varna","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025-12-02T13:59:46Z","date_published":"2025-12-02T13:59:46Z","updated_at":"2026-07-27T21:56:42Z","subjects":["stress, depressive experience, dialysis, chronic kidney disease (CKD)","Нефрология / Nephrology"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://repository.mu-varna.bg/handle/nls/4231","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Stavreva, Aleksandra","Ставрева, Александра"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2025-12-02T13:59:46Z","2025"]},{"key":"dc:publisher","label":"Institution","values":["Medical University of Varna"]},{"key":"dc:type","label":"Dc Type","values":["thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["stress, depressive experience, dialysis, chronic kidney disease (CKD)","Нефрология / Nephrology"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://repository.mu-varna.bg/handle/nls/4231"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The thesis aims to assess the role of psychological factors—stress, depressive experiences, and social support—in patients with chronic kidney disease (CKD) in both pre-dialysis and dialysis stages. The cohort includes 60 patients undergoing hemodialysis (HD) treatment in stage G5 and 30 patients diagnosed with CKD in stages G1–G4. The results indicate higher levels of stress and depressive experiences among dialysis-dependent patients compared to those in the pre-dialysis stage. Patients with CKD (G1–G4) exhibit significantly higher levels of social support indicators compared to the HD group. Correlation analysis reveals a statistically significant relationship between all listed manifestations of stress among patients in the end stage of CKD. A stronger positive correlation is observed among all indicators of social support in patients diagnosed with CKD. Regression analysis does not reveal statistically significant results regarding subjectively perceived psychological factors in relation to survival among dialysis-dependent patients. Only higher levels of anxiety are associated with reduced survival in this group. The findings support the need for implementing targeted activities and comprehensive educational programs aimed at preventing the development of psychological conditions that affect the psycho-emotional status of patients diagnosed with CKD, particularly at the initiation of HD treatment.","Целта на настоящия научен труд е да оцени ролята на психологическите фактори - стрес, депресивни преживявания и социална подкрепа при пациентите с хронично бъбречно заболяване (ХБЗ) в преддиализен и диализен стадий. Кохортата включва 60 пациенти, провеждащи хемодиализно (ХД) лечение в G5 стадий и 30 - диагностицирани с ХБЗ в G1-G4 стадий. Получените резултати показват по-високи нива на стрес и депресивни преживявания при диализно зависимите пациенти в сравнение с болните в преддиализен стадий. При пациентите с ХБЗ (G1–G4) се отчитат по-високи сигнификантни нива по показателите за социална подкрепа в сравнение с ХД-група. Проведеният корелационен анализ показва статистическа значима връзка между всички от изброените прояви на стрес сред пациентите в краен стадий на ХБЗ. Установява се по-силна правопропорционална връзка между всички признаци на социална подкрепа при диагностицираните болни с ХБЗ. От регресионния анализ не се отчитат статистически значими резултати при субективно възприеманите психологически фактори по отношение на преживяемостта при диализно зависимите болни. Единствено по-високите нива на проявата на безпокойствие при тях е свързана с намалена преживяемост. Резултатите подкрепят необходимостта от реализиране на дейности и подробно разяснителни програми, свързани с оглед превенция от развитие на психологически състояния, влияещи върху психо-емоционалния статус на пациентите, диагностицирани с ХБЗ и в момента на започване на ХД-лечение."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Analysis and Assessment of Psychological Factors in Patients with Chronic Kidney Disease in the Pre-Dialysis and Dialysis Stages // Анализ и оценка на психологичните фактори при пациенти с хронично бъбречно заболяване в преддиализен и диализен стадий"]}]}],"canonical_facts":{"dc:creator":["Stavreva, Aleksandra","Ставрева, Александра"],"dc:date":["2025-12-02T13:59:46Z","2025"],"dc:description":["The thesis aims to assess the role of psychological factors—stress, depressive experiences, and social support—in patients with chronic kidney disease (CKD) in both pre-dialysis and dialysis stages. The cohort includes 60 patients undergoing hemodialysis (HD) treatment in stage G5 and 30 patients diagnosed with CKD in stages G1–G4. The results indicate higher levels of stress and depressive experiences among dialysis-dependent patients compared to those in the pre-dialysis stage. Patients with CKD (G1–G4) exhibit significantly higher levels of social support indicators compared to the HD group. Correlation analysis reveals a statistically significant relationship between all listed manifestations of stress among patients in the end stage of CKD. A stronger positive correlation is observed among all indicators of social support in patients diagnosed with CKD. Regression analysis does not reveal statistically significant results regarding subjectively perceived psychological factors in relation to survival among dialysis-dependent patients. Only higher levels of anxiety are associated with reduced survival in this group. The findings support the need for implementing targeted activities and comprehensive educational programs aimed at preventing the development of psychological conditions that affect the psycho-emotional status of patients diagnosed with CKD, particularly at the initiation of HD treatment.","Целта на настоящия научен труд е да оцени ролята на психологическите фактори - стрес, депресивни преживявания и социална подкрепа при пациентите с хронично бъбречно заболяване (ХБЗ) в преддиализен и диализен стадий. Кохортата включва 60 пациенти, провеждащи хемодиализно (ХД) лечение в G5 стадий и 30 - диагностицирани с ХБЗ в G1-G4 стадий. Получените резултати показват по-високи нива на стрес и депресивни преживявания при диализно зависимите пациенти в сравнение с болните в преддиализен стадий. При пациентите с ХБЗ (G1–G4) се отчитат по-високи сигнификантни нива по показателите за социална подкрепа в сравнение с ХД-група. Проведеният корелационен анализ показва статистическа значима връзка между всички от изброените прояви на стрес сред пациентите в краен стадий на ХБЗ. Установява се по-силна правопропорционална връзка между всички признаци на социална подкрепа при диагностицираните болни с ХБЗ. От регресионния анализ не се отчитат статистически значими резултати при субективно възприеманите психологически фактори по отношение на преживяемостта при диализно зависимите болни. Единствено по-високите нива на проявата на безпокойствие при тях е свързана с намалена преживяемост. Резултатите подкрепят необходимостта от реализиране на дейности и подробно разяснителни програми, свързани с оглед превенция от развитие на психологически състояния, влияещи върху психо-емоционалния статус на пациентите, диагностицирани с ХБЗ и в момента на започване на ХД-лечение."],"dc:format":["application/pdf"],"dc:identifier":["http://repository.mu-varna.bg/handle/nls/4231"],"dc:publisher":["Medical University of Varna"],"dc:subject":["stress, depressive experience, dialysis, chronic kidney disease (CKD)","Нефрология / Nephrology"],"dc:title":["Analysis and Assessment of Psychological Factors in Patients with Chronic Kidney Disease in the Pre-Dialysis and Dialysis Stages // Анализ и оценка на психологичните фактори при пациенти с хронично бъбречно заболяване в преддиализен и диализен стадий"],"dc:type":["thesis"]},"updated_at":"2026-07-27T21:56:42Z"}