{"id":{"repo_id":"varna","oai_identifier":"oai:repository.mu-varna.bg:nls/4190"},"canonical_url":"https://search.dev.ndltd.org/etd/varna/oai:repository.mu-varna.bg:nls/4190","repository":{"repo_id":"varna","name":"Medical University of Varna","base_url":"https://repository.mu-varna.bg/oai/request"},"display":{"title":"Coronary Artery Pathology in Patients with Peri-implantitis // Патология на коронарните артерии при пациенти с периимплантит","abstract":"The thesis is focused on investigating the relationship between peri-implantitis — an inflammatory condition of the peri-implant tissues accompanied by bone resorption — and pathological changes in the coronary arteries. The study aims to evaluate whether patients with peri-implantitis exhibit a higher prevalence and more severe forms of coronary artery disease. Additionally, a comparison was made between coronary artery pathology in patients with peri-implantitis and those with periodontitis. Using clinical and laboratory (paraclinical) methods, including coronary angiography, the degree of coronary atherosclerosis was assessed, along with its potential association with systemic inflammation associated with peri-implantitis. General health status, peri-implant tissue condition, and various laboratory markers were also analysed. The results provide new evidence for the role of oral health in the pathogenesis of cardiovascular diseases and emphasise the importance of a multidisciplinary approach in their prevention and treatment.","abstract_html":"The thesis is focused on investigating the relationship between peri-implantitis — an inflammatory condition of the peri-implant tissues accompanied by bone resorption — and pathological changes in the coronary arteries. The study aims to evaluate whether patients with peri-implantitis exhibit a higher prevalence and more severe forms of coronary artery disease. Additionally, a comparison was made between coronary artery pathology in patients with peri-implantitis and those with periodontitis. Using clinical and laboratory (paraclinical) methods, including coronary angiography, the degree of coronary atherosclerosis was assessed, along with its potential association with systemic inflammation associated with peri-implantitis. General health status, peri-implant tissue condition, and various laboratory markers were also analysed. The results provide new evidence for the role of oral health in the pathogenesis of cardiovascular diseases and emphasise the importance of a multidisciplinary approach in their prevention and treatment.","abstract_has_math":false,"creators":["Slavova, Velislava","Славова, Велислава"],"institution":"Medical University of Varna","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025-10-31T09:36:54Z","date_published":"2025-10-31T09:36:54Z","updated_at":"2026-07-27T21:56:56Z","subjects":["peri-implantitis","coronary artery disease","oral health","Зъболечение / Dental Treatment"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://repository.mu-varna.bg/handle/nls/4190","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Slavova, Velislava","Славова, Велислава"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2025-10-31T09:36:54Z","2025"]},{"key":"dc:publisher","label":"Institution","values":["Medical University of Varna"]},{"key":"dc:type","label":"Dc Type","values":["thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["peri-implantitis","coronary artery disease","oral health","Зъболечение / Dental Treatment"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://repository.mu-varna.bg/handle/nls/4190"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The thesis is focused on investigating the relationship between peri-implantitis — an inflammatory condition of the peri-implant tissues accompanied by bone resorption — and pathological changes in the coronary arteries. The study aims to evaluate whether patients with peri-implantitis exhibit a higher prevalence and more severe forms of coronary artery disease. Additionally, a comparison was made between coronary artery pathology in patients with peri-implantitis and those with periodontitis. Using clinical and laboratory (paraclinical) methods, including coronary angiography, the degree of coronary atherosclerosis was assessed, along with its potential association with systemic inflammation associated with peri-implantitis. General health status, peri-implant tissue condition, and various laboratory markers were also analysed. The results provide new evidence for the role of oral health in the pathogenesis of cardiovascular diseases and emphasise the importance of a multidisciplinary approach in their prevention and treatment.","Дисертационният труд е насочена към изследване на връзката между периимплантит – възпалително заболяване на периимплатните тъкани, съпроводено с костна резорбция и патологичните промени в коронарните артерии. Целта на проучването е да се оцени дали пациентите с периимплантит проявяват по-висока честота и по-тежки форми на коронарна артериална болест. Отделно е направено и сравнение патологията на коронарните артерии при пациенти с периимплантит и такива с пародонтит. Чрез прилагане на клинични и лабораторни (параклинични), включително ангиографско изследване, се анализира степента на коронарна атеросклероза и нейната евентуална зависимост от системното възпаление, предизвикано от периимплантита. Сравни се общото здравословно състояние, състоянието на периимплантните тъкани и редица лабораторни показатели. Резултатите предоставят нови доказателства за ролята на оралното здраве в патогенезата на сърдечносъдовите заболявания и да подчертаят значението на мултидисциплинарния подход в превенцията и лечението им."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Coronary Artery Pathology in Patients with Peri-implantitis // Патология на коронарните артерии при пациенти с периимплантит"]}]}],"canonical_facts":{"dc:creator":["Slavova, Velislava","Славова, Велислава"],"dc:date":["2025-10-31T09:36:54Z","2025"],"dc:description":["The thesis is focused on investigating the relationship between peri-implantitis — an inflammatory condition of the peri-implant tissues accompanied by bone resorption — and pathological changes in the coronary arteries. The study aims to evaluate whether patients with peri-implantitis exhibit a higher prevalence and more severe forms of coronary artery disease. Additionally, a comparison was made between coronary artery pathology in patients with peri-implantitis and those with periodontitis. Using clinical and laboratory (paraclinical) methods, including coronary angiography, the degree of coronary atherosclerosis was assessed, along with its potential association with systemic inflammation associated with peri-implantitis. General health status, peri-implant tissue condition, and various laboratory markers were also analysed. The results provide new evidence for the role of oral health in the pathogenesis of cardiovascular diseases and emphasise the importance of a multidisciplinary approach in their prevention and treatment.","Дисертационният труд е насочена към изследване на връзката между периимплантит – възпалително заболяване на периимплатните тъкани, съпроводено с костна резорбция и патологичните промени в коронарните артерии. Целта на проучването е да се оцени дали пациентите с периимплантит проявяват по-висока честота и по-тежки форми на коронарна артериална болест. Отделно е направено и сравнение патологията на коронарните артерии при пациенти с периимплантит и такива с пародонтит. Чрез прилагане на клинични и лабораторни (параклинични), включително ангиографско изследване, се анализира степента на коронарна атеросклероза и нейната евентуална зависимост от системното възпаление, предизвикано от периимплантита. Сравни се общото здравословно състояние, състоянието на периимплантните тъкани и редица лабораторни показатели. Резултатите предоставят нови доказателства за ролята на оралното здраве в патогенезата на сърдечносъдовите заболявания и да подчертаят значението на мултидисциплинарния подход в превенцията и лечението им."],"dc:format":["application/pdf"],"dc:identifier":["http://repository.mu-varna.bg/handle/nls/4190"],"dc:publisher":["Medical University of Varna"],"dc:subject":["peri-implantitis","coronary artery disease","oral health","Зъболечение / Dental Treatment"],"dc:title":["Coronary Artery Pathology in Patients with Peri-implantitis // Патология на коронарните артерии при пациенти с периимплантит"],"dc:type":["thesis"]},"updated_at":"2026-07-27T21:56:56Z"}