Treatment of Medication-Induced Osteonecrosis of the Jaws, Using Platelet-Rich Fibrin PRF // Лечение на медикаментозно-индуцирана остеонекроза на челюстите с приложение на богат на тромбоцити фибрин PRF

Medication-induced osteonecrosis of the jaws (MRONJ) in an area of exposed bone, which does not heal in a period of more than eight weeks and affects patients underdoing medication therapy. These are mostly patients diagnosed with cancer and on intravenous treatment. The impact of the disease globally increases with the increase of medication prescribed. Currently, the treatment of MRONJ is still problematic, as effective treatment has not yet been developed. Surgical treatment is still one of the most trusted methods, although current updates are much needed, by means of scientific progress and technical advancement, which provide relatively easy application of growth factors in the field of oral and maxillofacial surgery. One of these advancements is the Platelet-rich Fibrin membrane, which could easily be obtained (extracted) in ambulatory conditions. Application of PRF in surgery is an alternative method of MIONJ treatment. Doham et al.(2006) develop an extraction protocol for PRF.

Grantor dc:publisher

Medical University of Varna

Year dc:date

2022

Authors dc:creator

• Tsolov, Rosen
• Цолов, Росен

• osteonecrosis of the jaws
• platelet-rich fibrin
• extraction protocol
• Зъболечение / Dental Treatment

Repository record dc:identifier

http://repository.mu-varna.bg/handle/nls/1851

OAI identifier oai:identifier

oai:repository.mu-varna.bg:nls/1851