{"id":{"repo_id":"uwtsd","oai_identifier":"oai:repository.uwtsd.ac.uk:4024"},"canonical_url":"https://search.dev.ndltd.org/etd/uwtsd/oai:repository.uwtsd.ac.uk:4024","repository":{"repo_id":"uwtsd","name":"University of Wales Trinity Saint David","base_url":"https://repository.uwtsd.ac.uk/cgi/oai2"},"display":{"title":"Exploring the Long-Term Effects of Vaping on Respiratory Health Among Adolescents: A Systematic Literature Review","abstract":"Background: Vaping has emerged as a widespread behaviour among adolescents globally, raising growing concerns regarding its long-term respiratory health implications. While e-cigarettes are often marketed as safer alternatives to conventional smoking, emerging evidence suggests that adolescent use may be associated with a range of adverse respiratory outcomes. Given the vulnerability of the adolescent respiratory system, a systematic synthesis of available evidence is crucial to inform public health, clinical practice, and regulatory policies. Aim: This review aimed to systematically evaluate and synthesise the long-term effects of vaping on respiratory health among adolescents aged 10–19 years. Methods: A systematic literature review was conducted in accordance with PRISMA 2020 guidelines. Electronic databases searched included PubMed, EBSCOhost, and ProQuest. Pre-defined inclusion and exclusion criteria were applied, focusing on primary studies involving adolescents and reporting respiratory outcomes. Methodological quality was assessed using the Coughlan, Cronin, and Ryan checklist. Data were extracted using a standardised form and synthesised thematically. Results: From 1,327 records initially identified, 12 studies met the final inclusion criteria. Six major themes emerged: (1) chronic respiratory symptoms (cough, wheeze, bronchitic symptoms, and asthma exacerbations), (2) pulmonary function impairment (notably reduced FEV1/FVC in vapers), (3) pathophysiological mechanisms (airway inflammation and oxidative stress), (4) second-hand vapour exposure, associated with increased asthma risk in non-vaping adolescents, (5) dose and duration of use, with frequent or prolonged vaping linked to more severe symptoms, and (6) vaping, addiction, and psychosocial influences, highlighting peer pressure, marketing, and nicotine dependence as factors exacerbating risks. Conclusion: The findings indicate that adolescent vaping is consistently associated with adverse respiratory outcomes, with dose–response relationships suggesting cumulative harm. Evidence of impaired lung function and second-hand exposure further underscores the public health relevance. Future longitudinal and experimental research is needed to establish causal mechanisms and inform targeted prevention strategies.","abstract_html":"Background: Vaping has emerged as a widespread behaviour among adolescents globally, raising growing concerns regarding its long-term respiratory health implications. While e-cigarettes are often marketed as safer alternatives to conventional smoking, emerging evidence suggests that adolescent use may be associated with a range of adverse respiratory outcomes. Given the vulnerability of the adolescent respiratory system, a systematic synthesis of available evidence is crucial to inform public health, clinical practice, and regulatory policies. Aim: This review aimed to systematically evaluate and synthesise the long-term effects of vaping on respiratory health among adolescents aged 10–19 years. Methods: A systematic literature review was conducted in accordance with PRISMA 2020 guidelines. Electronic databases searched included PubMed, EBSCOhost, and ProQuest. Pre-defined inclusion and exclusion criteria were applied, focusing on primary studies involving adolescents and reporting respiratory outcomes. Methodological quality was assessed using the Coughlan, Cronin, and Ryan checklist. Data were extracted using a standardised form and synthesised thematically. Results: From 1,327 records initially identified, 12 studies met the final inclusion criteria. Six major themes emerged: (1) chronic respiratory symptoms (cough, wheeze, bronchitic symptoms, and asthma exacerbations), (2) pulmonary function impairment (notably reduced FEV1/FVC in vapers), (3) pathophysiological mechanisms (airway inflammation and oxidative stress), (4) second-hand vapour exposure, associated with increased asthma risk in non-vaping adolescents, (5) dose and duration of use, with frequent or prolonged vaping linked to more severe symptoms, and (6) vaping, addiction, and psychosocial influences, highlighting peer pressure, marketing, and nicotine dependence as factors exacerbating risks. Conclusion: The findings indicate that adolescent vaping is consistently associated with adverse respiratory outcomes, with dose–response relationships suggesting cumulative harm. Evidence of impaired lung function and second-hand exposure further underscores the public health relevance. Future longitudinal and experimental research is needed to establish causal mechanisms and inform targeted prevention strategies.","abstract_has_math":false,"creators":["Opoku-Mensah, Yvonne"],"institution":"University of Wales Trinity Saint David","degree_name":"msc","degree_level":"masters","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025-11","date_published":"2025-11","updated_at":"2026-07-24T05:53:08Z","subjects":["HV Patholeg gymdeithasol. Lles cymdeithasol a chyhoeddus"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier.grantnumber","label":"Dc Identifier Grantnumber","values":["UWTSD"],"render_values":[{"text":"UWTSD","href":null,"code":true}]}]},"links":{"outbound_url":"https://doi.org/10.82227/repository.uwtsd.ac.uk.00004024","outbound_label":"DOI","outbound_source":"dc:identifier.doi"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.sponsor","label":"Sponsor","values":["University of Wales Trinity Saint David"]},{"key":"dc:creator","label":"Author","values":["Opoku-Mensah, Yvonne"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2025-11-19"]},{"key":"dc:date.issued","label":"Date","values":["2025-11"]},{"key":"dc:publisher.commercial","label":"Dc Publisher Commercial","values":["University of Wales Trinity Saint David"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Traethodau Meistr","Institute of Inner City Learning"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Wales Trinity Saint David"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://repository.uwtsd.ac.uk/id/eprint/4024/"]},{"key":"dc:type","label":"Dc Type","values":["Gosodiad"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["masters"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["msc"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["HV Patholeg gymdeithasol. Lles cymdeithasol a chyhoeddus"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.doi","label":"DOI","values":["10.82227/repository.uwtsd.ac.uk.00004024"]},{"key":"dc:identifier.grantnumber","label":"Dc Identifier Grantnumber","values":["UWTSD"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://repository.uwtsd.ac.uk/id/eprint/4024/1/Opoku-Mensah_Y_MSc_Thesis.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Background: Vaping has emerged as a widespread behaviour among adolescents globally, raising growing concerns regarding its long-term respiratory health implications. While e-cigarettes are often marketed as safer alternatives to conventional smoking, emerging evidence suggests that adolescent use may be associated with a range of adverse respiratory outcomes. Given the vulnerability of the adolescent respiratory system, a systematic synthesis of available evidence is crucial to inform public health, clinical practice, and regulatory policies. Aim: This review aimed to systematically evaluate and synthesise the long-term effects of vaping on respiratory health among adolescents aged 10–19 years. Methods: A systematic literature review was conducted in accordance with PRISMA 2020 guidelines. Electronic databases searched included PubMed, EBSCOhost, and ProQuest. Pre-defined inclusion and exclusion criteria were applied, focusing on primary studies involving adolescents and reporting respiratory outcomes. Methodological quality was assessed using the Coughlan, Cronin, and Ryan checklist. Data were extracted using a standardised form and synthesised thematically. Results: From 1,327 records initially identified, 12 studies met the final inclusion criteria. Six major themes emerged: (1) chronic respiratory symptoms (cough, wheeze, bronchitic symptoms, and asthma exacerbations), (2) pulmonary function impairment (notably reduced FEV1/FVC in vapers), (3) pathophysiological mechanisms (airway inflammation and oxidative stress), (4) second-hand vapour exposure, associated with increased asthma risk in non-vaping adolescents, (5) dose and duration of use, with frequent or prolonged vaping linked to more severe symptoms, and (6) vaping, addiction, and psychosocial influences, highlighting peer pressure, marketing, and nicotine dependence as factors exacerbating risks. Conclusion: The findings indicate that adolescent vaping is consistently associated with adverse respiratory outcomes, with dose–response relationships suggesting cumulative harm. Evidence of impaired lung function and second-hand exposure further underscores the public health relevance. Future longitudinal and experimental research is needed to establish causal mechanisms and inform targeted prevention strategies."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Exploring the Long-Term Effects of Vaping on Respiratory Health Among Adolescents: A Systematic Literature Review"]}]}],"canonical_facts":{"dc:contributor.sponsor":["University of Wales Trinity Saint David"],"dc:creator":["Opoku-Mensah, Yvonne"],"dc:date":["2025-11-19"],"dc:date.issued":["2025-11"],"dc:description.abstract":["Background: Vaping has emerged as a widespread behaviour among adolescents globally, raising growing concerns regarding its long-term respiratory health implications. While e-cigarettes are often marketed as safer alternatives to conventional smoking, emerging evidence suggests that adolescent use may be associated with a range of adverse respiratory outcomes. Given the vulnerability of the adolescent respiratory system, a systematic synthesis of available evidence is crucial to inform public health, clinical practice, and regulatory policies. Aim: This review aimed to systematically evaluate and synthesise the long-term effects of vaping on respiratory health among adolescents aged 10–19 years. Methods: A systematic literature review was conducted in accordance with PRISMA 2020 guidelines. Electronic databases searched included PubMed, EBSCOhost, and ProQuest. Pre-defined inclusion and exclusion criteria were applied, focusing on primary studies involving adolescents and reporting respiratory outcomes. Methodological quality was assessed using the Coughlan, Cronin, and Ryan checklist. Data were extracted using a standardised form and synthesised thematically. Results: From 1,327 records initially identified, 12 studies met the final inclusion criteria. Six major themes emerged: (1) chronic respiratory symptoms (cough, wheeze, bronchitic symptoms, and asthma exacerbations), (2) pulmonary function impairment (notably reduced FEV1/FVC in vapers), (3) pathophysiological mechanisms (airway inflammation and oxidative stress), (4) second-hand vapour exposure, associated with increased asthma risk in non-vaping adolescents, (5) dose and duration of use, with frequent or prolonged vaping linked to more severe symptoms, and (6) vaping, addiction, and psychosocial influences, highlighting peer pressure, marketing, and nicotine dependence as factors exacerbating risks. Conclusion: The findings indicate that adolescent vaping is consistently associated with adverse respiratory outcomes, with dose–response relationships suggesting cumulative harm. Evidence of impaired lung function and second-hand exposure further underscores the public health relevance. Future longitudinal and experimental research is needed to establish causal mechanisms and inform targeted prevention strategies."],"dc:format":["text"],"dc:identifier.doi":["10.82227/repository.uwtsd.ac.uk.00004024"],"dc:identifier.grantnumber":["UWTSD"],"dc:identifier.uri":["https://repository.uwtsd.ac.uk/id/eprint/4024/1/Opoku-Mensah_Y_MSc_Thesis.pdf"],"dc:publisher.commercial":["University of Wales Trinity Saint David"],"dc:publisher.department":["Traethodau Meistr","Institute of Inner City Learning"],"dc:publisher.institution":["University of Wales Trinity Saint David"],"dc:relation.isreferencedby":["https://repository.uwtsd.ac.uk/id/eprint/4024/"],"dc:subject":["HV Patholeg gymdeithasol. Lles cymdeithasol a chyhoeddus"],"dc:title":["Exploring the Long-Term Effects of Vaping on Respiratory Health Among Adolescents: A Systematic Literature Review"],"dc:type":["Gosodiad"],"dc:type.qualificationlevel":["masters"],"dc:type.qualificationname":["msc"]},"updated_at":"2026-07-24T05:53:08Z"}