{"id":{"repo_id":"uwo","oai_identifier":"oai:uwo.scholaris.ca:20.500.14721/38862"},"canonical_url":"https://search.dev.ndltd.org/etd/uwo/oai:uwo.scholaris.ca:20.500.14721/38862","repository":{"repo_id":"uwo","name":"Western University","base_url":"https://uwo.scholaris.ca/server/oai/request"},"display":{"title":"Is Precision Treatment Possible for Depression?","abstract":"Depression, a leading cause of disability worldwide, can be successfully treated by several evidence-based interventions. However, individual responses to these treatments vary significantly, and many individuals undergo multiple therapies before finding what works best for them. Precision treatment for depression aims to address these challenges by identifying effective treatments based on individual characteristics. In doing so, precision treatment has the potential to reduce trial-and-error prescribing, shorten the time to remission, and lower the global burden of depression. However, despite decades of research, precision treatment has yet to be fully realized for depression and its clinical utility remains limited. This article provides examples of recent and relevant attempts at identifying predictors of differential treatment response and raises some methodological, conceptual, and practical concerns of implementing precision treatment for depression. Future directions and clinical implications for advancing personalized approaches to depression treatment are also discussed.","abstract_html":"Depression, a leading cause of disability worldwide, can be successfully treated by several evidence-based interventions. However, individual responses to these treatments vary significantly, and many individuals undergo multiple therapies before finding what works best for them. Precision treatment for depression aims to address these challenges by identifying effective treatments based on individual characteristics. In doing so, precision treatment has the potential to reduce trial-and-error prescribing, shorten the time to remission, and lower the global burden of depression. However, despite decades of research, precision treatment has yet to be fully realized for depression and its clinical utility remains limited. This article provides examples of recent and relevant attempts at identifying predictors of differential treatment response and raises some methodological, conceptual, and practical concerns of implementing precision treatment for depression. Future directions and clinical implications for advancing personalized approaches to depression treatment are also discussed.","abstract_has_math":false,"creators":["Rain, Sarina","Dozois, David J. A."],"institution":"Canadian Psychological Association","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Dozois, David J. 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However, significant practical and conceptual challenges have delayed its widespread application. Continued research and a focused effort to address these barriers are essential for precision treatment for depression to become a reality in clinical practice."]},{"key":"dc:description.abstract","label":"Abstract","values":["Depression, a leading cause of disability worldwide, can be successfully treated by several evidence-based interventions. However, individual responses to these treatments vary significantly, and many individuals undergo multiple therapies before finding what works best for them. Precision treatment for depression aims to address these challenges by identifying effective treatments based on individual characteristics. In doing so, precision treatment has the potential to reduce trial-and-error prescribing, shorten the time to remission, and lower the global burden of depression. However, despite decades of research, precision treatment has yet to be fully realized for depression and its clinical utility remains limited. This article provides examples of recent and relevant attempts at identifying predictors of differential treatment response and raises some methodological, conceptual, and practical concerns of implementing precision treatment for depression. Future directions and clinical implications for advancing personalized approaches to depression treatment are also discussed."]},{"key":"dc:title","label":"Title","values":["Is Precision Treatment Possible for Depression?"]}]}],"canonical_facts":{"dc:contributor.advisor":["Dozois, David J. A."],"dc:creator":["Rain, Sarina","Dozois, David J. 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