{"id":{"repo_id":"uwo","oai_identifier":"oai:uwo.scholaris.ca:20.500.14721/34309"},"canonical_url":"https://search.dev.ndltd.org/etd/uwo/oai:uwo.scholaris.ca:20.500.14721/34309","repository":{"repo_id":"uwo","name":"Western University","base_url":"https://uwo.scholaris.ca/server/oai/request"},"display":{"title":"Stability of long multiple-rod constructs and dual-rod constructs in the thoracic spine: a biomechanical cadaveric study","abstract":"Spinal fusion to correct spinal deformity is typically performed with a 2-rod construct spanning the targeted area of fusion. More evidence is starting to emerge around the utility of multiple-rod constructs (typically 3 or more rods) to increase the stiffness and stability of a spinal fusion construct. Much of this work has focused on the lumbar spine, and little has been published around how these constructs behave in a long construct spanning the thoracic spine. The purpose of this thesis is to compare the stability of a two-rod (dual-rod) construct (DRC) to a four-rod (multiple-rod) construct (MRC) in cadaveric thoracic spines. Nine intact human cadaveric thoracic spines (T1-T12) were instrumented with either a DRC or MRC, and biomechanical testing was then carried out to compare range of motion (ROM) and stiffness between these two constructs. Results demonstrated comparable absolute total ROM and stiffness between DRCs and MRCs, and this was consistent across all measured vertebral levels. However, after undergoing a 1-hour bodyweight simulation fatigue test, DRCs exhibited an increase in flexion/extension ROM and decrease in stiffness while MRCs did not. Overall, these findings support previous clinical and biomechanical results in the lumbar spine and adult spinal deformity literature that MRCs can potentially be used to increase the stability of thoracic spine constructs.","abstract_html":"Spinal fusion to correct spinal deformity is typically performed with a 2-rod construct spanning the targeted area of fusion. More evidence is starting to emerge around the utility of multiple-rod constructs (typically 3 or more rods) to increase the stiffness and stability of a spinal fusion construct. Much of this work has focused on the lumbar spine, and little has been published around how these constructs behave in a long construct spanning the thoracic spine. The purpose of this thesis is to compare the stability of a two-rod (dual-rod) construct (DRC) to a four-rod (multiple-rod) construct (MRC) in cadaveric thoracic spines. Nine intact human cadaveric thoracic spines (T1-T12) were instrumented with either a DRC or MRC, and biomechanical testing was then carried out to compare range of motion (ROM) and stiffness between these two constructs. Results demonstrated comparable absolute total ROM and stiffness between DRCs and MRCs, and this was consistent across all measured vertebral levels. However, after undergoing a 1-hour bodyweight simulation fatigue test, DRCs exhibited an increase in flexion/extension ROM and decrease in stiffness while MRCs did not. Overall, these findings support previous clinical and biomechanical results in the lumbar spine and adult spinal deformity literature that MRCs can potentially be used to increase the stability of thoracic spine constructs.","abstract_has_math":false,"creators":["Herrington, Brandon J"],"institution":"The University of Western Ontario","degree_name":"M Sc","degree_level":null,"degree_discipline":"Surgery","degree_department":null,"school":null,"contributors":[],"advisors":["Rodrigues Fernandes, Renan","Rasoulinejad, Parham","Bailey, Chris"],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024-08-27","date_published":"2024-08-27","updated_at":"2026-07-27T21:55:54Z","subjects":["cadaver","spinal fusion","adult spinal deformity","dual-rod construct","multiple-rod construct","proximal junctional kyphosis"],"languages":["en_ca"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/20.500.14721/34309","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Rodrigues Fernandes, Renan","Rasoulinejad, Parham","Bailey, Chris"]},{"key":"dc:creator","label":"Author","values":["Herrington, Brandon J"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2025-07-10T20:02:04Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2025-07-10T20:02:04Z"]},{"key":"dc:date.issued","label":"Date","values":["2024-08-27"]},{"key":"dc:publisher","label":"Institution","values":["The University of Western Ontario"]},{"key":"dc:type","label":"Dc Type","values":["thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Surgery"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M Sc"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["cadaver","spinal fusion","adult spinal deformity","dual-rod construct","multiple-rod construct","proximal junctional kyphosis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_ca"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/20.500.14721/34309"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The thesis cover page in the PDF document includes references to Western University’s previous institutional repository platform, known as Scholarship@Western, and links to that platform (beginning with ir.lib.uwo.ca). In citing or referring to this thesis, use the DOI or handle from this page instead. Sample citation: Author name, \"Thesis title.\" (Year). Western University Open Repository. https://doi.org/10.71858/123456."]},{"key":"dc:description.abstract","label":"Abstract","values":["Spinal fusion to correct spinal deformity is typically performed with a 2-rod construct spanning the targeted area of fusion. More evidence is starting to emerge around the utility of multiple-rod constructs (typically 3 or more rods) to increase the stiffness and stability of a spinal fusion construct. Much of this work has focused on the lumbar spine, and little has been published around how these constructs behave in a long construct spanning the thoracic spine. The purpose of this thesis is to compare the stability of a two-rod (dual-rod) construct (DRC) to a four-rod (multiple-rod) construct (MRC) in cadaveric thoracic spines. Nine intact human cadaveric thoracic spines (T1-T12) were instrumented with either a DRC or MRC, and biomechanical testing was then carried out to compare range of motion (ROM) and stiffness between these two constructs. Results demonstrated comparable absolute total ROM and stiffness between DRCs and MRCs, and this was consistent across all measured vertebral levels. However, after undergoing a 1-hour bodyweight simulation fatigue test, DRCs exhibited an increase in flexion/extension ROM and decrease in stiffness while MRCs did not. Overall, these findings support previous clinical and biomechanical results in the lumbar spine and adult spinal deformity literature that MRCs can potentially be used to increase the stability of thoracic spine constructs."]},{"key":"dc:title","label":"Title","values":["Stability of long multiple-rod constructs and dual-rod constructs in the thoracic spine: a biomechanical cadaveric study"]}]}],"canonical_facts":{"dc:contributor.advisor":["Rodrigues Fernandes, Renan","Rasoulinejad, Parham","Bailey, Chris"],"dc:creator":["Herrington, Brandon J"],"dc:date.accessioned":["2025-07-10T20:02:04Z"],"dc:date.available":["2025-07-10T20:02:04Z"],"dc:date.issued":["2024-08-27"],"dc:description":["The thesis cover page in the PDF document includes references to Western University’s previous institutional repository platform, known as Scholarship@Western, and links to that platform (beginning with ir.lib.uwo.ca). In citing or referring to this thesis, use the DOI or handle from this page instead. 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Nine intact human cadaveric thoracic spines (T1-T12) were instrumented with either a DRC or MRC, and biomechanical testing was then carried out to compare range of motion (ROM) and stiffness between these two constructs. Results demonstrated comparable absolute total ROM and stiffness between DRCs and MRCs, and this was consistent across all measured vertebral levels. However, after undergoing a 1-hour bodyweight simulation fatigue test, DRCs exhibited an increase in flexion/extension ROM and decrease in stiffness while MRCs did not. Overall, these findings support previous clinical and biomechanical results in the lumbar spine and adult spinal deformity literature that MRCs can potentially be used to increase the stability of thoracic spine constructs."],"dc:identifier.uri":["https://hdl.handle.net/20.500.14721/34309"],"dc:language.iso":["en_ca"],"dc:publisher":["The University of Western Ontario"],"dc:subject":["cadaver","spinal fusion","adult spinal deformity","dual-rod construct","multiple-rod construct","proximal junctional kyphosis"],"dc:title":["Stability of long multiple-rod constructs and dual-rod constructs in the thoracic spine: a biomechanical cadaveric study"],"dc:type":["thesis"],"thesis:degree_discipline":["Surgery"],"thesis:degree_name":["M Sc"]},"updated_at":"2026-07-27T21:55:54Z"}