Brain Injury and Inflammation and Placental Inflammation in Response to Repetitive Umbilical Cord Occlusions in the Near Term Ovine Fetus
type: CreativeWork
description: We hypothesized that repetitive umbilical cord occlusions (UCOs) leading to severe acidemia will stimulate a placental and fetal inflammatory response associated with brain injury, which will be exacerbated by chronic hypoxemia and low-grade infection. Chronically instrumented fetal sheep served as controls or underwent repetitive UCOs for up to 4 hours or until fetal arterial pH was2saturation pre-UCOs of >55% and
abstract: We hypothesized that repetitive umbilical cord occlusions (UCOs) leading to severe acidemia will stimulate a placental and fetal inflammatory response associated with brain injury, which will be exacerbated by chronic hypoxemia and low-grade infection. Chronically instrumented fetal sheep served as controls or underwent repetitive UCOs for up to 4 hours or until fetal arterial pH was2saturation pre-UCOs of >55% and
author: Xu, Alex
language: en_ca
keywords: Fetal hypoxia, placental inflammation, LPS, microglia, brain apoptosis, interleukin 6
date published: 2015-11-27
date modified: 2026-07-27T21:56:09Z
provider: Western University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: The University of Western Ontario

PropertyValue
property ID: Handle
value: https://hdl.handle.net/20.500.14721/33507