{"id":{"repo_id":"uwo","oai_identifier":"oai:uwo.scholaris.ca:20.500.14721/33289"},"canonical_url":"https://search.dev.ndltd.org/etd/uwo/oai:uwo.scholaris.ca:20.500.14721/33289","repository":{"repo_id":"uwo","name":"Western University","base_url":"https://uwo.scholaris.ca/server/oai/request"},"display":{"title":"Mechanistic Studies of Donor-Acceptor Cyclopropanes","abstract":"Cyclopropane 1,1-diesters have been investigated as a source of donor-acceptor cyclopropanes, providing an understanding of the mechanism of reaction between these cyclopropanes and nitrosoarenes, as well as azo dicarboxylates. Cross-over experiments have been utilized to provide key pieces of experimental evidence that help generate a theoretical model of the reactions. By understanding these reactions with precision, the avenue to expand the reaction scope and develop other useful reactions is opened up. This allows the chemistry to be better utilized, providing easier access to important molecules when needed, and contributes to advancing the field of synthetic organic chemistry. In addition, cyclobutane 1,1-diesters were also investigated as a source of donor-acceptor cyclobutanes. Specifically, their use in cycloaddition reactions has been developed to include the reaction of cyclobutanes with cis-diazenes, providing access to hexahydropyridazines. These compounds are synthesized in an efficient manner and are known to contain biologically active properties.","abstract_html":"Cyclopropane 1,1-diesters have been investigated as a source of donor-acceptor cyclopropanes, providing an understanding of the mechanism of reaction between these cyclopropanes and nitrosoarenes, as well as azo dicarboxylates. Cross-over experiments have been utilized to provide key pieces of experimental evidence that help generate a theoretical model of the reactions. By understanding these reactions with precision, the avenue to expand the reaction scope and develop other useful reactions is opened up. This allows the chemistry to be better utilized, providing easier access to important molecules when needed, and contributes to advancing the field of synthetic organic chemistry. In addition, cyclobutane 1,1-diesters were also investigated as a source of donor-acceptor cyclobutanes. Specifically, their use in cycloaddition reactions has been developed to include the reaction of cyclobutanes with cis-diazenes, providing access to hexahydropyridazines. These compounds are synthesized in an efficient manner and are known to contain biologically active properties.","abstract_has_math":false,"creators":["Chidley, Tristan"],"institution":"The University of Western Ontario","degree_name":"M Sc","degree_level":null,"degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":[],"advisors":["Brian L. Pagenkopf"],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-08-18","date_published":"2015-08-18","updated_at":"2026-07-27T21:55:58Z","subjects":["donor-acceptor cyclopropanes","donor-acceptor cyclobutanes","cyclopropane","cyclobutane","tetrahydro-1","2-oxazine"],"languages":["en_ca"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/20.500.14721/33289","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Brian L. 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In citing or referring to this thesis, use the DOI or handle from this page instead. Sample citation: Author name, \"Thesis title.\" (Year). Western University Open Repository. https://doi.org/10.71858/123456."]},{"key":"dc:description.abstract","label":"Abstract","values":["Cyclopropane 1,1-diesters have been investigated as a source of donor-acceptor cyclopropanes, providing an understanding of the mechanism of reaction between these cyclopropanes and nitrosoarenes, as well as azo dicarboxylates. Cross-over experiments have been utilized to provide key pieces of experimental evidence that help generate a theoretical model of the reactions. By understanding these reactions with precision, the avenue to expand the reaction scope and develop other useful reactions is opened up. This allows the chemistry to be better utilized, providing easier access to important molecules when needed, and contributes to advancing the field of synthetic organic chemistry. In addition, cyclobutane 1,1-diesters were also investigated as a source of donor-acceptor cyclobutanes. Specifically, their use in cycloaddition reactions has been developed to include the reaction of cyclobutanes with cis-diazenes, providing access to hexahydropyridazines. These compounds are synthesized in an efficient manner and are known to contain biologically active properties."]},{"key":"dc:title","label":"Title","values":["Mechanistic Studies of Donor-Acceptor Cyclopropanes"]}]}],"canonical_facts":{"dc:contributor.advisor":["Brian L. Pagenkopf"],"dc:creator":["Chidley, Tristan"],"dc:date.accessioned":["2025-07-10T19:51:40Z"],"dc:date.available":["2025-07-10T19:51:40Z"],"dc:date.issued":["2015-08-18"],"dc:description":["The thesis cover page in the PDF document includes references to Western University’s previous institutional repository platform, known as Scholarship@Western, and links to that platform (beginning with ir.lib.uwo.ca). In citing or referring to this thesis, use the DOI or handle from this page instead. Sample citation: Author name, \"Thesis title.\" (Year). Western University Open Repository. https://doi.org/10.71858/123456."],"dc:description.abstract":["Cyclopropane 1,1-diesters have been investigated as a source of donor-acceptor cyclopropanes, providing an understanding of the mechanism of reaction between these cyclopropanes and nitrosoarenes, as well as azo dicarboxylates. Cross-over experiments have been utilized to provide key pieces of experimental evidence that help generate a theoretical model of the reactions. By understanding these reactions with precision, the avenue to expand the reaction scope and develop other useful reactions is opened up. This allows the chemistry to be better utilized, providing easier access to important molecules when needed, and contributes to advancing the field of synthetic organic chemistry. In addition, cyclobutane 1,1-diesters were also investigated as a source of donor-acceptor cyclobutanes. Specifically, their use in cycloaddition reactions has been developed to include the reaction of cyclobutanes with cis-diazenes, providing access to hexahydropyridazines. These compounds are synthesized in an efficient manner and are known to contain biologically active properties."],"dc:identifier.uri":["https://hdl.handle.net/20.500.14721/33289"],"dc:language.iso":["en_ca"],"dc:publisher":["The University of Western Ontario"],"dc:subject":["donor-acceptor cyclopropanes","donor-acceptor cyclobutanes","cyclopropane","cyclobutane","tetrahydro-1","2-oxazine"],"dc:title":["Mechanistic Studies of Donor-Acceptor Cyclopropanes"],"dc:type":["thesis"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_name":["M Sc"]},"updated_at":"2026-07-27T21:55:58Z"}