{"id":{"repo_id":"uwo","oai_identifier":"oai:uwo.scholaris.ca:20.500.14721/27896"},"canonical_url":"https://search.dev.ndltd.org/etd/uwo/oai:uwo.scholaris.ca:20.500.14721/27896","repository":{"repo_id":"uwo","name":"Western University","base_url":"https://uwo.scholaris.ca/server/oai/request"},"display":{"title":"The Moderating Effect of Physical Activity on the Association between White Matter Hyperintensities and Gait Characteristics","abstract":"The objectives of this thesis were; 1) to assess the effect of white matter hyperintensities (WMH) burden on motor outcomes among older individuals in presence and absence of overt neurological conditions and 2) to evaluate whether physical activity (PA) moderated the association between WMH and gait velocity and stride time variability (STV), under single and dual-task conditions, in a geriatric clinic sample. Study 1 systematically reviewed the literature demonstrating that greater WMH burden was associated with predefined motor outcomes. Notably, gait velocity emerged as a well-studied characteristic. Study 2 confirmed that WMH negatively affected gait velocity. STV and dual-task gait conditions did not reveal significance. Additionally, PA did not moderate the association between WMH and gait velocity, although conditional effects showed significance for low and moderate levels of PA. This finding extends support for the efficacy of physical activity in attenuating the effects of WMH on mobility.","abstract_html":"The objectives of this thesis were; 1) to assess the effect of white matter hyperintensities (WMH) burden on motor outcomes among older individuals in presence and absence of overt neurological conditions and 2) to evaluate whether physical activity (PA) moderated the association between WMH and gait velocity and stride time variability (STV), under single and dual-task conditions, in a geriatric clinic sample. Study 1 systematically reviewed the literature demonstrating that greater WMH burden was associated with predefined motor outcomes. Notably, gait velocity emerged as a well-studied characteristic. Study 2 confirmed that WMH negatively affected gait velocity. STV and dual-task gait conditions did not reveal significance. Additionally, PA did not moderate the association between WMH and gait velocity, although conditional effects showed significance for low and moderate levels of PA. This finding extends support for the efficacy of physical activity in attenuating the effects of WMH on mobility.","abstract_has_math":false,"creators":["Lingum, Navena Rebecca"],"institution":"The University of Western Ontario","degree_name":"M Sc","degree_level":null,"degree_discipline":"Kinesiology","degree_department":null,"school":null,"contributors":[],"advisors":["Manuel Montero-Odasso"],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017-10-25","date_published":"2017-10-25","updated_at":"2026-07-27T21:56:16Z","subjects":["White Matter Hyperintensities","Physical Activity","Gait Velocity","Dual-Task","Older Adults","Stride Time Variability"],"languages":["en_ca"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/20.500.14721/27896","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Manuel Montero-Odasso"]},{"key":"dc:creator","label":"Author","values":["Lingum, Navena Rebecca"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2025-07-10T15:33:47Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2025-07-10T15:33:47Z"]},{"key":"dc:date.issued","label":"Date","values":["2017-10-25"]},{"key":"dc:publisher","label":"Institution","values":["The University of Western Ontario"]},{"key":"dc:type","label":"Dc Type","values":["thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Kinesiology"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M Sc"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["White Matter Hyperintensities","Physical Activity","Gait Velocity","Dual-Task","Older Adults","Stride Time Variability"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_ca"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/20.500.14721/27896"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The thesis cover page in the PDF document includes references to Western University’s previous institutional repository platform, known as Scholarship@Western, and links to that platform (beginning with ir.lib.uwo.ca). In citing or referring to this thesis, use the DOI or handle from this page instead. Sample citation: Author name, \"Thesis title.\" (Year). Western University Open Repository. https://doi.org/10.71858/123456."]},{"key":"dc:description.abstract","label":"Abstract","values":["The objectives of this thesis were; 1) to assess the effect of white matter hyperintensities (WMH) burden on motor outcomes among older individuals in presence and absence of overt neurological conditions and 2) to evaluate whether physical activity (PA) moderated the association between WMH and gait velocity and stride time variability (STV), under single and dual-task conditions, in a geriatric clinic sample. Study 1 systematically reviewed the literature demonstrating that greater WMH burden was associated with predefined motor outcomes. Notably, gait velocity emerged as a well-studied characteristic. Study 2 confirmed that WMH negatively affected gait velocity. STV and dual-task gait conditions did not reveal significance. Additionally, PA did not moderate the association between WMH and gait velocity, although conditional effects showed significance for low and moderate levels of PA. This finding extends support for the efficacy of physical activity in attenuating the effects of WMH on mobility."]},{"key":"dc:title","label":"Title","values":["The Moderating Effect of Physical Activity on the Association between White Matter Hyperintensities and Gait Characteristics"]}]}],"canonical_facts":{"dc:contributor.advisor":["Manuel Montero-Odasso"],"dc:creator":["Lingum, Navena Rebecca"],"dc:date.accessioned":["2025-07-10T15:33:47Z"],"dc:date.available":["2025-07-10T15:33:47Z"],"dc:date.issued":["2017-10-25"],"dc:description":["The thesis cover page in the PDF document includes references to Western University’s previous institutional repository platform, known as Scholarship@Western, and links to that platform (beginning with ir.lib.uwo.ca). In citing or referring to this thesis, use the DOI or handle from this page instead. Sample citation: Author name, \"Thesis title.\" (Year). Western University Open Repository. https://doi.org/10.71858/123456."],"dc:description.abstract":["The objectives of this thesis were; 1) to assess the effect of white matter hyperintensities (WMH) burden on motor outcomes among older individuals in presence and absence of overt neurological conditions and 2) to evaluate whether physical activity (PA) moderated the association between WMH and gait velocity and stride time variability (STV), under single and dual-task conditions, in a geriatric clinic sample. Study 1 systematically reviewed the literature demonstrating that greater WMH burden was associated with predefined motor outcomes. Notably, gait velocity emerged as a well-studied characteristic. Study 2 confirmed that WMH negatively affected gait velocity. STV and dual-task gait conditions did not reveal significance. Additionally, PA did not moderate the association between WMH and gait velocity, although conditional effects showed significance for low and moderate levels of PA. This finding extends support for the efficacy of physical activity in attenuating the effects of WMH on mobility."],"dc:identifier.uri":["https://hdl.handle.net/20.500.14721/27896"],"dc:language.iso":["en_ca"],"dc:publisher":["The University of Western Ontario"],"dc:subject":["White Matter Hyperintensities","Physical Activity","Gait Velocity","Dual-Task","Older Adults","Stride Time Variability"],"dc:title":["The Moderating Effect of Physical Activity on the Association between White Matter Hyperintensities and Gait Characteristics"],"dc:type":["thesis"],"thesis:degree_discipline":["Kinesiology"],"thesis:degree_name":["M Sc"]},"updated_at":"2026-07-27T21:56:16Z"}