Impact of Prolonged Sitting on Cognitive Function: Implications for Cardio-metabolic Risk

<p><strong>Purpose: </strong>To determine if prolonged sitting negatively impacts cognitive function, cerebral perfusion, and central cardiovascular hemodynamics; and secondly, to test whether weight or physical activity status alters this response. <strong>Methods:</strong> Participants (N=20, age=26±7; BMI=30±7 kg/m²; 7 female) were taken through 3 hrs of sitting followed by a 10-min walk (treadmill). Cognitive function was assessed during sitting (10, 60, 120, and 180 mins) and following the walk using a color/word Stroop test. Cerebral perfusion was measured via near infrared spectroscopy (total hemoglobin—tHb). Central cardiovascular hemodynamics and aortic stiffness (pulse wave velocity—PWV) were measured using the SphygmoCor XCEL device before, during and after sitting. Body mass index, %-bodyfat, and accelerometry data were used to characterize weight and physical activity status. <strong>Results</strong>: Following sitting, there was no change in Stroop completion time; however, both Color and Text times significantly decreased following the walk (e.g., Color Time: 10 mins sitting, 19±3 sec vs. Post walk, 16.7±3.6 sec, pConclusion: These findings suggest that prolonged sitting does not alter cognitive function or cerebral perfusion, but sitting does increase aortic stiffness in normal weight individuals. Walking can improve cognitive function, an effect possibly related to increases in cerebral perfusion.</p>

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Masters Thesis

Discipline thesis:degree_discipline

Kinesiology

Year dc:date.available

2018

Author dc:creator

• Miller, Sabina

Contributors dc:contributor

• Daniel Credeur
• Stephanie McCoy
• David Dolbow

• prolonged sitting
• cognitive function
• physical activity
• Other Medicine and Health Sciences

Repository record dc:identifier

https://aquila.usm.edu/masters_theses/368

OAI identifier oai:identifier

oai:aquila.usm.edu:masters_theses-1382