{"id":{"repo_id":"uoit","oai_identifier":"oai:ontariotechu.scholaris.ca:10155/1613"},"canonical_url":"https://search.dev.ndltd.org/etd/uoit/oai:ontariotechu.scholaris.ca:10155/1613","repository":{"repo_id":"uoit","name":"Ontario Institute of Technology","base_url":"https://ontariotechu.scholaris.ca/server/oai/request"},"display":{"title":"Identifying salivary biomarkers associated with prolonged sitting","abstract":"The effect of prolonged sitting on salivary biomarker concentrations is relatively unexplored. The purpose of this work was to identify novel biomarkers, detectable in the saliva in response to prolonged and interrupted bouts of sitting. Participants completed three sessions. The first session included a baseline saliva sample and maximal exercise test. The remaining two sessions were performed in random order. One, a prolonged sitting session (4-hours of sitting), and the other, an interrupted sitting session (4-hours of sitting with 3-minute moderate-intensity walking interruptions every 27 minutes). Saliva samples were collected pre- and post-session. A human cytokine antibody array was then used to detect biomarkers present in the saliva. A total of 26 biomarkers were detectable in the saliva of young, healthy males and females. Prolonged and interrupted sitting lead to changes in salivary biomarker concentrations, with variations dependent on sex.","abstract_html":"The effect of prolonged sitting on salivary biomarker concentrations is relatively unexplored. The purpose of this work was to identify novel biomarkers, detectable in the saliva in response to prolonged and interrupted bouts of sitting. Participants completed three sessions. The first session included a baseline saliva sample and maximal exercise test. The remaining two sessions were performed in random order. One, a prolonged sitting session (4-hours of sitting), and the other, an interrupted sitting session (4-hours of sitting with 3-minute moderate-intensity walking interruptions every 27 minutes). Saliva samples were collected pre- and post-session. A human cytokine antibody array was then used to detect biomarkers present in the saliva. A total of 26 biomarkers were detectable in the saliva of young, healthy males and females. Prolonged and interrupted sitting lead to changes in salivary biomarker concentrations, with variations dependent on sex.","abstract_has_math":false,"creators":["Meens Miller, Emmeline"],"institution":"University of Ontario Institute of Technology","degree_name":"Master of Health Sciences (MHSc)","degree_level":null,"degree_discipline":"Kinesiology","degree_department":null,"school":null,"contributors":[],"advisors":["Dogra, Shilpa"],"committee_chairs":[],"committee_members":[],"year":2023,"date_issued":"2023-04-01","date_published":"2023-04-01","updated_at":"2026-07-24T05:35:22Z","subjects":["Sedentary behaviour","Biomarkers","Cytokines","Growth factors","Inflammation"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/10155/1613","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Dogra, Shilpa"]},{"key":"dc:creator","label":"Author","values":["Meens Miller, Emmeline"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2023-04-25T16:55:09Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2023-04-25T16:55:09Z"]},{"key":"dc:date.issued","label":"Date","values":["2023-04-01"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Kinesiology"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Health Sciences (MHSc)"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Ontario Institute of Technology"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Sedentary behaviour","Biomarkers","Cytokines","Growth factors","Inflammation"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/10155/1613"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The effect of prolonged sitting on salivary biomarker concentrations is relatively unexplored. The purpose of this work was to identify novel biomarkers, detectable in the saliva in response to prolonged and interrupted bouts of sitting. Participants completed three sessions. The first session included a baseline saliva sample and maximal exercise test. The remaining two sessions were performed in random order. One, a prolonged sitting session (4-hours of sitting), and the other, an interrupted sitting session (4-hours of sitting with 3-minute moderate-intensity walking interruptions every 27 minutes). Saliva samples were collected pre- and post-session. A human cytokine antibody array was then used to detect biomarkers present in the saliva. A total of 26 biomarkers were detectable in the saliva of young, healthy males and females. Prolonged and interrupted sitting lead to changes in salivary biomarker concentrations, with variations dependent on sex."]},{"key":"dc:title","label":"Title","values":["Identifying salivary biomarkers associated with prolonged sitting"]}]}],"canonical_facts":{"dc:contributor.advisor":["Dogra, Shilpa"],"dc:creator":["Meens Miller, Emmeline"],"dc:date.accessioned":["2023-04-25T16:55:09Z"],"dc:date.available":["2023-04-25T16:55:09Z"],"dc:date.issued":["2023-04-01"],"dc:description.abstract":["The effect of prolonged sitting on salivary biomarker concentrations is relatively unexplored. The purpose of this work was to identify novel biomarkers, detectable in the saliva in response to prolonged and interrupted bouts of sitting. Participants completed three sessions. The first session included a baseline saliva sample and maximal exercise test. The remaining two sessions were performed in random order. One, a prolonged sitting session (4-hours of sitting), and the other, an interrupted sitting session (4-hours of sitting with 3-minute moderate-intensity walking interruptions every 27 minutes). Saliva samples were collected pre- and post-session. A human cytokine antibody array was then used to detect biomarkers present in the saliva. A total of 26 biomarkers were detectable in the saliva of young, healthy males and females. Prolonged and interrupted sitting lead to changes in salivary biomarker concentrations, with variations dependent on sex."],"dc:identifier.uri":["https://hdl.handle.net/10155/1613"],"dc:language.iso":["en"],"dc:subject":["Sedentary behaviour","Biomarkers","Cytokines","Growth factors","Inflammation"],"dc:title":["Identifying salivary biomarkers associated with prolonged sitting"],"dc:type":["Thesis"],"thesis:degree_discipline":["Kinesiology"],"thesis:degree_name":["Master of Health Sciences (MHSc)"],"thesis:institution_name":["University of Ontario Institute of Technology"]},"updated_at":"2026-07-24T05:35:22Z"}