Bioaccumulation of Triclocarban, Triclosan, and Methyl-triclosan in a North Texas Wastewater Treatment Plant Receiving Stream and Effects of Triclosan on Algal Lipid Synthesis.

Triclosan (TCS) and triclocarban (TCC), widely used antimicrobial agents found in numerous consumer products, are incompletely removed by wastewater treatment plant (WWTP) processing. Methyl-triclosan (M-TCS) is a more lipophilic metabolite of its parent compound, TCS. The focus of this study was to quantify bioaccumulation factors (BAFs) for TCS, M-TCS, and TCC in Pecan creek, the receiving stream for the City of Denton, Texas WWTP by using field samples mostly composed of the alga Cladophora sp. and the caged snail Helisoma trivolvis as test species. Additionally, TCS effects on E. coli and Arabidopsis have been shown to reduce fatty acid biosynthesis and total lipid content by inhibiting the trans-2 enoyl- ACP reductase. The lipid synthesis pathway effects of TCS on field samples of Cladophora spp. were also investigated in this study by using [2-14C]acetate radiolabeling procedures. Preliminary results indicate high TCS concentrations are toxic to lipid biosynthesis and reduce [2-14C]acetate incorporation into total lipids. These results have led to the concern that chronic exposure of algae in receiving streams to environmentally relevant TCS concentrations might affect their nutrient value. If consumer growth is limited, trophic cascade strength may be affected and serve to limit population growth and reproduction of herbivores in these riparian systems.

Grantor dc:publisher

University of North Texas

Year dc:date

2007

Author dc:creator

• Coogan, Melinda Ann

Contributors dc:contributor

• La Point, Thomas W., 1949-
• Venables, Barney J.
• Chapman, Kent D.
• Banks, Kenneth E.
• Lewis, Michael A.

• bioaccumulation
• triclocarban
• trioclosan
• methyl-triclosan
• Water quality -- Texas -- Pecan Creek.
• Water -- Pollution -- Toxicology -- Texas -- Pecan Creek.
• Sewage disposal plants -- Environmental aspects -- Texas -- Denton.
• Drugs -- Environmental aspects -- Texas -- Denton.

Statement dc:rights

• Public
• Copyright
• Coogan, Melinda Ann
• Copyright is held by the author, unless otherwise noted. All rights reserved.

Language dc:language

English

Identifier

oclc: 191865727
untcat: b3362322
https://digital.library.unt.edu/ark:/67531/metadc3986/
ark: ark:/67531/metadc3986

OAI identifier oai:identifier

info:ark/67531/metadc3986