{"id":{"repo_id":"unt","oai_identifier":"info:ark/67531/metadc2853"},"canonical_url":"https://search.dev.ndltd.org/etd/unt/info:ark/67531/metadc2853","repository":{"repo_id":"unt","name":"University of North Texas","base_url":"https://digital.library.unt.edu/oai/"},"display":{"title":"A preliminary study of the effects of selective-serotonin re-uptake inhibitors (SSRIs) on central auditory processing","abstract":"his study compared auditory behavioral and physiological measures among three subject groups: 1) Normal control subjects, 2) subjects who were on a prescribed SSRI for depression, and 3) subjects who were prescribed an SSRI for depression, but were not medicated at the time of testing. Test measures included: Standard audiological tests (audiometry and tympanometry), electrophysiological procedures for analysis of auditory- evoked brainstem and late responses, and standardized behavioral speech tests (SCAN-A, SSI, and the low predictability sentence list of the R-SPIN). Analysis of results indicated a statistically significant increase of group mean amplitude of the ABR peak V, from 15dBnSL to 55dBnSL, in the non-medicated group compared to controls. Also, the non-medicated group scored significantly less favorably than controls on the most challenging listening condition (-20 MCR) of the SSI, in the left ear. Although other test measures indicated consistent differences between these two groups, they were not, however, significant.","abstract_html":"his study compared auditory behavioral and physiological measures among three subject groups: 1) Normal control subjects, 2) subjects who were on a prescribed SSRI for depression, and 3) subjects who were prescribed an SSRI for depression, but were not medicated at the time of testing. Test measures included: Standard audiological tests (audiometry and tympanometry), electrophysiological procedures for analysis of auditory- evoked brainstem and late responses, and standardized behavioral speech tests (SCAN-A, SSI, and the low predictability sentence list of the R-SPIN). Analysis of results indicated a statistically significant increase of group mean amplitude of the ABR peak V, from 15dBnSL to 55dBnSL, in the non-medicated group compared to controls. Also, the non-medicated group scored significantly less favorably than controls on the most challenging listening condition (-20 MCR) of the SSI, in the left ear. Although other test measures indicated consistent differences between these two groups, they were not, however, significant.","abstract_has_math":false,"creators":["Bishop, Charles E."],"institution":"University of North Texas","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Gopal, Kamakshi V.","Lu, Fang-Ling","Henoch, Miriam A.","Cokely, Jeffrey A"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2001,"date_issued":"2001-08","date_published":"2001-08","updated_at":"2026-07-24T05:34:52Z","subjects":["Auditory perception.","Serotonin uptake inhibitors.","serotonin","behavioral tests","depression","auditory processing","auditory-evoked potentials"],"languages":["English"],"rights":["Use restricted to UNT Community","Copyright","Bishop Charles E.","Copyright is held by the author, unless otherwise noted. 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Analysis of results indicated a statistically significant increase of group mean amplitude of the ABR peak V, from 15dBnSL to 55dBnSL, in the non-medicated group compared to controls. Also, the non-medicated group scored significantly less favorably than controls on the most challenging listening condition (-20 MCR) of the SSI, in the left ear. Although other test measures indicated consistent differences between these two groups, they were not, however, significant."]},{"key":"dc:format","label":"Dc Format","values":["Text"]},{"key":"dc:title","label":"Title","values":["A preliminary study of the effects of selective-serotonin re-uptake inhibitors (SSRIs) on central auditory processing"]}]}],"canonical_facts":{"dc:contributor":["Gopal, Kamakshi V.","Lu, Fang-Ling","Henoch, Miriam A.","Cokely, Jeffrey A"],"dc:creator":["Bishop, Charles E."],"dc:date":["2001-08"],"dc:description":["his study compared auditory behavioral and physiological measures among three subject groups: 1) Normal control subjects, 2) subjects who were on a prescribed SSRI for depression, and 3) subjects who were prescribed an SSRI for depression, but were not medicated at the time of testing. Test measures included: Standard audiological tests (audiometry and tympanometry), electrophysiological procedures for analysis of auditory- evoked brainstem and late responses, and standardized behavioral speech tests (SCAN-A, SSI, and the low predictability sentence list of the R-SPIN). Analysis of results indicated a statistically significant increase of group mean amplitude of the ABR peak V, from 15dBnSL to 55dBnSL, in the non-medicated group compared to controls. Also, the non-medicated group scored significantly less favorably than controls on the most challenging listening condition (-20 MCR) of the SSI, in the left ear. 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