RNA CoMPASS: RNA Comprehensive Multi-Processor Analysis System for Sequencing

<p>The main theme of this dissertation is to develop a distributed computational pipeline for processing next-generation RNA sequencing (RNA-seq) data. RNA-seq experiments generate hundreds of millions of short reads for each DNA/RNA sample. There are many existing bioinformatics tools developed for the analysis and visualization of this data, but very large studies present computational and organizational challenges that are difficult to overcome manually. We designed a comprehensive pipeline for the analysis of RNA sequencing which leverages many existing tools and parallel computing technology to facilitate the analysis of extremely large studies. RNA CoMPASS provides a web-based graphical user interface and distributed computational pipeline including endogenous transcriptome quantification and additionally the investigation of exogenous sequences.</p>

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Computer Science

Year

2012

Author dc:creator

• Xu, Guorong

Contributors dc:contributor

• Christopher Taylor

• Parallel Computing, GUI User Interface, Transciptomic, Next-Generation Sequencing, RNA-seq Pipeline

Repository record dc:identifier

https://scholarworks.uno.edu/td/1531

OAI identifier oai:identifier

oai:scholarworks.uno.edu:td-2524