SEA: a novel computational and GUI software pipeline for detecting activated biological sub-pathways

<p> <p>With the ever increasing amount of high-throughput molecular profile data, biologists need versatile tools to enable them to quickly and succinctly analyze their data. Furthermore, pathway databases have grown increasingly robust with the KEGG database at the forefront. Previous tools have color-coded the genes on different pathways using differential expression analysis. Unfortunately, they do not adequately capture the relationships of the genes amongst one another. Structure Enrichment Analysis (SEA) thus seeks to take biological analysis to the next level. SEA accomplishes this goal by highlighting for users the sub-pathways of a biological pathways that best correspond to their molecular profile data in an easy to use GUI interface.</p> </p> <p> <p> <p> <p> <p> <p> <p> <p> </p> </p> </p> </p> </p> </p> </p> </p> <p> <p> <p> <p> <p> <p> <p> </p> </p> </p> </p> </p> </p> </p> <p> <p> <p> <p> <p> <p> </p> </p> </p> </p> </p> </p> <p> <p> <p> <p> <p> </p> </p> </p> </p> </p> <p> <p> <p> <p> </p> </p> </p> </p> <p> <p> <p> </p> </p> </p> <p> <p> </p> </p> <p> </p>

Name thesis:degree_name

M.S.

Level thesis:degree_level

Thesis-Restricted

Discipline thesis:degree_discipline

Computer Science

Year

2011

Author dc:creator

• Judeh, Thair

Contributors dc:contributor

• Zhu, Dongxiao
• Summa, Christopher M.
• DePano, Nathanael A.

• Network Partitioning, Network Reconstruction, Structure Enrichment Analysis, Community
• Computer Sciences

Repository record dc:identifier

https://scholarworks.uno.edu/td/463

OAI identifier oai:identifier

oai:scholarworks.uno.edu:td-1255