IMPACT OF MEAL FREQUENCY ON APPETITE AND BLOOD MARKERS OF HEALTH IN OBESE WOMEN UTILIZING AN EQUI-HYPOCALORIC DIET DURING A BEHAVIORAL WEIGHT LOSS INTERVENTION
type: CreativeWork
description: Background: Obesity prevalence is a global pandemic and a public health concern. Beneficial weight loss strategies are needed for obesity management. Increased daily meal frequency (MF) is often associated with improvements in blood-markers of health and appetite control during weight loss; however, this has not been confirmed using portion-controlled meal products to reduce underreporting error. Objective: The purpose of this study was to determine if increased MF can be a beneficial treatment strategy for weight loss in obese women by determining the changes of total ghrelin, blood glucose, insulin, lipid concentrations, and sensations of hunger and satiety due to an equi-hypocaloric diet intervention during a two meals per day sequence (2 MF) versus a three meals and three snacks per day sequence (6 MF) using portion-controlled products. Design: Eleven (N = 11) obese female subjects (BMI 39.1 ± 7.6 kg/m2) ages 52 ± 7 years completed a six-week study using a randomized cross-over design. Subjects were randomized to either the 2 MF or 6 MF treatment condition for two-weeks, had a two-week washout of three meals and one snack per day, and then alternated treatment conditions. Results: All subjects lost a similar percentage of body weight 6.6 ± 1.6% (6.2 ± 1.9 kg) which was not significantly different (P > 0.05) between the 2 MF and 6 MF conditions. Percent change analysis in fat-free mass (FFM) showed significant differences between conditions. Results showed 3.3 ± 2.6% decrease in FFM following the 2 MF condition, while following the 6 MF condition there was an average increase of 1.2 ± 1.7% in FFM (P ≤ 0.05). There were no significant differences between conditions for fasting and area-under-the-curve (AUC) values of glucose, insulin, and total-ghrelin. Fasting high-density lipoprotein cholesterol (HDL-C) concentrations were significantly lower than baseline during the 6 MF condition (49 ± 10 vs. 53 ± 12 mg/dL, respectively) where the percent change in HDL-C durin…
abstract: Background: Obesity prevalence is a global pandemic and a public health concern. Beneficial weight loss strategies are needed for obesity management. Increased daily meal frequency (MF) is often associated with improvements in blood-markers of health and appetite control during weight loss; however, this has not been confirmed using portion-controlled meal products to reduce underreporting error. Objective: The purpose of this study was to determine if increased MF can be a beneficial treatment strategy for weight loss in obese women by determining the changes of total ghrelin, blood glucose, insulin, lipid concentrations, and sensations of hunger and satiety due to an equi-hypocaloric diet intervention during a two meals per day sequence (2 MF) versus a three meals and three snacks per day sequence (6 MF) using portion-controlled products. Design: Eleven (N = 11) obese female subjects (BMI 39.1 ± 7.6 kg/m2) ages 52 ± 7 years completed a six-week study using a randomized cross-over design. Subjects were randomized to either the 2 MF or 6 MF treatment condition for two-weeks, had a two-week washout of three meals and one snack per day, and then alternated treatment conditions. Results: All subjects lost a similar percentage of body weight 6.6 ± 1.6% (6.2 ± 1.9 kg) which was not significantly different (P > 0.05) between the 2 MF and 6 MF conditions. Percent change analysis in fat-free mass (FFM) showed significant differences between conditions. Results showed 3.3 ± 2.6% decrease in FFM following the 2 MF condition, while following the 6 MF condition there was an average increase of 1.2 ± 1.7% in FFM (P ≤ 0.05). There were no significant differences between conditions for fasting and area-under-the-curve (AUC) values of glucose, insulin, and total-ghrelin. Fasting high-density lipoprotein cholesterol (HDL-C) concentrations were significantly lower than baseline during the 6 MF condition (49 ± 10 vs. 53 ± 12 mg/dL, respectively) where the percent change in HDL-C durin…
author: Kulovitz, Michelle
language: English
keywords: meal frequency, obese, eating frequency, ghrelin, hypocaloric-diet, weight loss, behavior
date published: 2016-02-02T08:00:00Z
date modified: 2026-07-24T05:26:22Z
provider: University of New Mexico
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of New Mexico

PropertyValue
property ID: Handle
value: http://hdl.handle.net/1928/31763