A comparison of the functional efficacy of osteoarthritic knee joints following viscosupplementation treatment

The purpose of this study was to compare two viscosupplementation products, Hyalgan and Synvisc, that may be used to treat osteoarthritis (OA) of the knee. Hyalgan and Synvisc, have both been studied extensively against NSAIDS and placebos and have both yielded significantly greater improvements in reducing the symptoms associated with OA. Forty-one patients diagnosed with OA of the knee volunteered to participate in this study. Each patient received the standard protocol of lateral injections with extended knee of 2 ml of either Hyalgan or Synvisc using a 20 gauge needle. Product efficacy and functional outcome were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and was administered to every participant prior to their first injection and again at two and four months post final injection. The results suggest that both viscosupplementation products are comparably effective in decreasing pain and stiffness, and increasing daily function.

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Kinesiology

Grantor dc:publisher

University of Nevada, Las Vegas

Year

2001

Author dc:creator

• Buford, Stephanie Beasley

Contributors dc:contributor

• Suzanne Pero

Statement dc:rights

• IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/

Language dc:language

English

Identifier

https://oasis.library.unlv.edu/rtds/1275

OAI identifier oai:identifier

oai:oasis.library.unlv.edu:rtds-2274