{"id":{"repo_id":"unlv","oai_identifier":"oai:oasis.library.unlv.edu:rtds-1002"},"canonical_url":"https://search.dev.ndltd.org/etd/unlv/oai:oasis.library.unlv.edu:rtds-1002","repository":{"repo_id":"unlv","name":"University of Nevada - Las Vegas","base_url":"https://oasis.library.unlv.edu/do/oai/"},"display":{"title":"Heat shock proteins as indicators of environmental stress","abstract":"In order to determine whether heat shock proteins (HSP) can be used as indicators of environmental stress in the mammalian organism Peromyscus leucopus, three doses of each of two chemical stresses, cadmium chloride and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), were given intraperitoneally for 14 days. Proteins extracted from liver samples were compared by one-dimensional gel electrophoresis to liver protein samples from heat shocked and control animals. HSPs of 105,78, and 43 kDa were cadmium inducible. Non-heat shocked cadmium inducible proteins of 118, 55, and 47 kDa were seen. 2,4,5-T induced an increase in a 91 kDa protein. Low level cadmium induction of HSPs suggests useful applications in toxicological and general environmental tests.","abstract_html":"In order to determine whether heat shock proteins (HSP) can be used as indicators of environmental stress in the mammalian organism Peromyscus leucopus, three doses of each of two chemical stresses, cadmium chloride and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), were given intraperitoneally for 14 days. Proteins extracted from liver samples were compared by one-dimensional gel electrophoresis to liver protein samples from heat shocked and control animals. HSPs of 105,78, and 43 kDa were cadmium inducible. Non-heat shocked cadmium inducible proteins of 118, 55, and 47 kDa were seen. 2,4,5-T induced an increase in a 91 kDa protein. Low level cadmium induction of HSPs suggests useful applications in toxicological and general environmental tests.","abstract_has_math":false,"creators":["Castle, Arthur Louis"],"institution":"University of Nevada, Las Vegas","degree_name":"Master of Science (MS)","degree_level":"Thesis","degree_discipline":"Biological Science","degree_department":null,"school":null,"contributors":["R. Keith Dupre","Penny S. Amy"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1997,"date_issued":"1997-01-01T08:00:00Z","date_published":"1997-01-01T08:00:00Z","updated_at":"2026-07-24T05:23:59Z","subjects":[],"languages":["English"],"rights":["IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["https://oasis.library.unlv.edu/rtds/3"],"render_values":[{"text":"https://oasis.library.unlv.edu/rtds/3","href":"https://oasis.library.unlv.edu/rtds/3","code":true}]}]},"links":{"outbound_url":"https://doi.org/10.25669/bk3b-bfu9","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["R. Keith Dupre","Penny S. 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Non-heat shocked cadmium inducible proteins of 118, 55, and 47 kDa were seen. 2,4,5-T induced an increase in a 91 kDa protein. Low level cadmium induction of HSPs suggests useful applications in toxicological and general environmental tests."]},{"key":"dc:format","label":"Dc Format","values":["pdf"]},{"key":"dc:title","label":"Title","values":["Heat shock proteins as indicators of environmental stress"]}]}],"canonical_facts":{"dc:contributor":["R. Keith Dupre","Penny S. Amy"],"dc:creator":["Castle, Arthur Louis"],"dc:description.abstract":["In order to determine whether heat shock proteins (HSP) can be used as indicators of environmental stress in the mammalian organism Peromyscus leucopus, three doses of each of two chemical stresses, cadmium chloride and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), were given intraperitoneally for 14 days. Proteins extracted from liver samples were compared by one-dimensional gel electrophoresis to liver protein samples from heat shocked and control animals. HSPs of 105,78, and 43 kDa were cadmium inducible. Non-heat shocked cadmium inducible proteins of 118, 55, and 47 kDa were seen. 2,4,5-T induced an increase in a 91 kDa protein. Low level cadmium induction of HSPs suggests useful applications in toxicological and general environmental tests."],"dc:format":["pdf"],"dc:identifier":["10.25669/bk3b-bfu9","https://oasis.library.unlv.edu/rtds/3","https://oasis.library.unlv.edu/context/rtds/article/1002/viewcontent/uc.pdf"],"dc:language":["English"],"dc:publisher":["University of Nevada, Las Vegas"],"dc:rights":["IN COPYRIGHT. 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