{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/98322"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/98322","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Flexible, stretchable, biointegrated arrays of electronic thermal sensors and actuators for advancements in clinical medicine","abstract":"Continuous, precision measurements of thermal information related to the human body can provide significant insights into important physiological phenomena, such as blood flow changes, stress, infection and thermoregulation. However, technologies to-date have either been hindered by a high sensitivity to motion artifacts, or have been too bulky and intrusive to be viable for ubiquitous, continuous use outside of a clinic. In addition to mechanical bulk, current skin-mounted technologies for measurements of skin properties do not provide spatial mapping, which is critical to arriving at the most important results. Here we present a class of devices that conform to skin in an intimate, non-intrusive way to provide high precision mapping of temperature and thermal transport signals on skin and other soft tissues. We demonstrate arrays of ultrathin (total thickness <5 µm), flexible, stretchable, skin-conforming devices that map temperatures to a precision (<20 mK) exceeding that of sophisticated infrared cameras for clinical research. We establish the foundational mechanical, electrical and thermal physics and associated design strategies that are necessary for high performance device function. We extend these techniques to the spatial mapping of thermal transport properties on skin, validated in clinical studies at external facilities with comparisons to commercial tools. Additional applications of the physical principles in varied designs enable a new form of minimally invasive continuous blood flow mapping, as well as designs towards the continuous measurement of core body temperature. Specialized mechanical design techniques, which enable reliable transfer printing of devices with arbitrary geometries without sacrificing stretchability, enable additional classes of stretchable electronics with features down to 1.5 µm. Extensions of the design, fabrication and thermal transport principles enable the printing of ultrathin electronic sensor and actuator arrays onto superelastic surgical guidewires down to 350 µm in diameter.","abstract_html":"Continuous, precision measurements of thermal information related to the human body can provide significant insights into important physiological phenomena, such as blood flow changes, stress, infection and thermoregulation. However, technologies to-date have either been hindered by a high sensitivity to motion artifacts, or have been too bulky and intrusive to be viable for ubiquitous, continuous use outside of a clinic. In addition to mechanical bulk, current skin-mounted technologies for measurements of skin properties do not provide spatial mapping, which is critical to arriving at the most important results. Here we present a class of devices that conform to skin in an intimate, non-intrusive way to provide high precision mapping of temperature and thermal transport signals on skin and other soft tissues. We demonstrate arrays of ultrathin (total thickness &lt;5 µm), flexible, stretchable, skin-conforming devices that map temperatures to a precision (&lt;20 mK) exceeding that of sophisticated infrared cameras for clinical research. We establish the foundational mechanical, electrical and thermal physics and associated design strategies that are necessary for high performance device function. We extend these techniques to the spatial mapping of thermal transport properties on skin, validated in clinical studies at external facilities with comparisons to commercial tools. Additional applications of the physical principles in varied designs enable a new form of minimally invasive continuous blood flow mapping, as well as designs towards the continuous measurement of core body temperature. Specialized mechanical design techniques, which enable reliable transfer printing of devices with arbitrary geometries without sacrificing stretchability, enable additional classes of stretchable electronics with features down to 1.5 µm. Extensions of the design, fabrication and thermal transport principles enable the printing of ultrathin electronic sensor and actuator arrays onto superelastic surgical guidewires down to 350 µm in diameter.","abstract_has_math":false,"creators":["Webb, Richard Chad"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Materials Science & Engr","degree_department":null,"school":null,"contributors":["Rogers, John A.","Cahill, David G.","Cunningham, Brian T.","Kilian, Kristopher A."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017-09-29T17:52:41Z","date_published":"2017-09-29T17:52:41Z","updated_at":"2026-07-22T22:24:35Z","subjects":["Flexible electronics","Stretchable electronics","Biosensors"],"languages":["en"],"rights":["Copyright 2015 Richard Chad Webb"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/98322","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Rogers, John A.","Cahill, David G.","Cunningham, Brian T.","Kilian, Kristopher A."]},{"key":"dc:creator","label":"Author","values":["Webb, Richard Chad"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2017-09-29T17:52:41Z","2015-07-14","2015-08"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Materials Science & Engr"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Flexible electronics","Stretchable electronics","Biosensors"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2015 Richard Chad Webb"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/98322"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Continuous, precision measurements of thermal information related to the human body can provide significant insights into important physiological phenomena, such as blood flow changes, stress, infection and thermoregulation. However, technologies to-date have either been hindered by a high sensitivity to motion artifacts, or have been too bulky and intrusive to be viable for ubiquitous, continuous use outside of a clinic. In addition to mechanical bulk, current skin-mounted technologies for measurements of skin properties do not provide spatial mapping, which is critical to arriving at the most important results. Here we present a class of devices that conform to skin in an intimate, non-intrusive way to provide high precision mapping of temperature and thermal transport signals on skin and other soft tissues. We demonstrate arrays of ultrathin (total thickness <5 µm), flexible, stretchable, skin-conforming devices that map temperatures to a precision (<20 mK) exceeding that of sophisticated infrared cameras for clinical research. We establish the foundational mechanical, electrical and thermal physics and associated design strategies that are necessary for high performance device function. We extend these techniques to the spatial mapping of thermal transport properties on skin, validated in clinical studies at external facilities with comparisons to commercial tools. Additional applications of the physical principles in varied designs enable a new form of minimally invasive continuous blood flow mapping, as well as designs towards the continuous measurement of core body temperature. Specialized mechanical design techniques, which enable reliable transfer printing of devices with arbitrary geometries without sacrificing stretchability, enable additional classes of stretchable electronics with features down to 1.5 µm. Extensions of the design, fabrication and thermal transport principles enable the printing of ultrathin electronic sensor and actuator arrays onto superelastic surgical guidewires down to 350 µm in diameter.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-08-01","The student, Richard Webb, accepted the attached license on 2015-07-10 at 11:06.","The student, Richard Webb, submitted this Dissertation for approval on 2015-07-10 at 13:20.","This Dissertation was approved for publication on 2015-07-14 at 15:05.","DSpace SAF Submission Ingestion Package generated from Vireo submission #8370 on 2017-09-29 at 11:12:46","Made available in DSpace on 2017-09-29T17:52:41Z (GMT). No. of bitstreams: 8 WEBB-DISSERTATION-2015.pdf: 8505298 bytes, checksum: 5912136a3b2b32e359a708453e7b6d12 (MD5) Movie C1.mp4: 10407804 bytes, checksum: e45f1966e51510c25bf2873262357967 (MD5) Movie C2.mp4: 21661011 bytes, checksum: 18940d5b6ef232e7067f4de9eab7e605 (MD5) Movie C3.mp4: 8471090 bytes, checksum: f8e5abe4e19827047f399a4ef233c5d3 (MD5) Movie C4.mp4: 845224 bytes, checksum: c7f29e290c585271afcab92260145365 (MD5) Webb_Richard.docx: 28162573 bytes, checksum: fc1c762ac7a2b9dbf3498112627afff2 (MD5) LICENSE.txt: 4209 bytes, checksum: 4fc76ba847d736eb58edf2a96fc70e7c (MD5) Webb Copyright Letters.pdf: 700330 bytes, checksum: ec29031945ec787f50c7bb914b2107d2 (MD5) Previous issue date: 2015-07-14","Embargo set by: Colleen Fallaw for item 103530 Lift date: 2019-09-29T17:52:45Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system","Open Restriction set for Item 103530 on 2018-01-10T15:10:09Z with date null by astein@illinois.edu.","Open Restriction set for Item 103530 on 2018-01-10T15:10:14Z with date null by astein@illinois.edu.","Open"]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Flexible, stretchable, biointegrated arrays of electronic thermal sensors and actuators for advancements in clinical medicine"]}]}],"canonical_facts":{"dc:contributor":["Rogers, John A.","Cahill, David G.","Cunningham, Brian T.","Kilian, Kristopher A."],"dc:creator":["Webb, Richard Chad"],"dc:date":["2017-09-29T17:52:41Z","2015-07-14","2015-08"],"dc:description":["Continuous, precision measurements of thermal information related to the human body can provide significant insights into important physiological phenomena, such as blood flow changes, stress, infection and thermoregulation. However, technologies to-date have either been hindered by a high sensitivity to motion artifacts, or have been too bulky and intrusive to be viable for ubiquitous, continuous use outside of a clinic. In addition to mechanical bulk, current skin-mounted technologies for measurements of skin properties do not provide spatial mapping, which is critical to arriving at the most important results. Here we present a class of devices that conform to skin in an intimate, non-intrusive way to provide high precision mapping of temperature and thermal transport signals on skin and other soft tissues. We demonstrate arrays of ultrathin (total thickness <5 µm), flexible, stretchable, skin-conforming devices that map temperatures to a precision (<20 mK) exceeding that of sophisticated infrared cameras for clinical research. We establish the foundational mechanical, electrical and thermal physics and associated design strategies that are necessary for high performance device function. We extend these techniques to the spatial mapping of thermal transport properties on skin, validated in clinical studies at external facilities with comparisons to commercial tools. Additional applications of the physical principles in varied designs enable a new form of minimally invasive continuous blood flow mapping, as well as designs towards the continuous measurement of core body temperature. Specialized mechanical design techniques, which enable reliable transfer printing of devices with arbitrary geometries without sacrificing stretchability, enable additional classes of stretchable electronics with features down to 1.5 µm. Extensions of the design, fabrication and thermal transport principles enable the printing of ultrathin electronic sensor and actuator arrays onto superelastic surgical guidewires down to 350 µm in diameter.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-08-01","The student, Richard Webb, accepted the attached license on 2015-07-10 at 11:06.","The student, Richard Webb, submitted this Dissertation for approval on 2015-07-10 at 13:20.","This Dissertation was approved for publication on 2015-07-14 at 15:05.","DSpace SAF Submission Ingestion Package generated from Vireo submission #8370 on 2017-09-29 at 11:12:46","Made available in DSpace on 2017-09-29T17:52:41Z (GMT). No. of bitstreams: 8 WEBB-DISSERTATION-2015.pdf: 8505298 bytes, checksum: 5912136a3b2b32e359a708453e7b6d12 (MD5) Movie C1.mp4: 10407804 bytes, checksum: e45f1966e51510c25bf2873262357967 (MD5) Movie C2.mp4: 21661011 bytes, checksum: 18940d5b6ef232e7067f4de9eab7e605 (MD5) Movie C3.mp4: 8471090 bytes, checksum: f8e5abe4e19827047f399a4ef233c5d3 (MD5) Movie C4.mp4: 845224 bytes, checksum: c7f29e290c585271afcab92260145365 (MD5) Webb_Richard.docx: 28162573 bytes, checksum: fc1c762ac7a2b9dbf3498112627afff2 (MD5) LICENSE.txt: 4209 bytes, checksum: 4fc76ba847d736eb58edf2a96fc70e7c (MD5) Webb Copyright Letters.pdf: 700330 bytes, checksum: ec29031945ec787f50c7bb914b2107d2 (MD5) Previous issue date: 2015-07-14","Embargo set by: Colleen Fallaw for item 103530 Lift date: 2019-09-29T17:52:45Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system","Open Restriction set for Item 103530 on 2018-01-10T15:10:09Z with date null by astein@illinois.edu.","Open Restriction set for Item 103530 on 2018-01-10T15:10:14Z with date null by astein@illinois.edu.","Open"],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/2142/98322"],"dc:language":["en"],"dc:rights":["Copyright 2015 Richard Chad Webb"],"dc:subject":["Flexible electronics","Stretchable electronics","Biosensors"],"dc:title":["Flexible, stretchable, biointegrated arrays of electronic thermal sensors and actuators for advancements in clinical medicine"],"dc:type":["text"],"thesis:degree_discipline":["Materials Science & Engr"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:24:35Z"}