{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/98107"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/98107","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Selective molecular transport in nanopore systems","abstract":"A detailed characterization of the physics of novel nanopore systems has the potential to revolutionize water filtration, nanofluidics, and biomolecule detection technologies. I give my characterizations of five nanopore systems as my dissertation. First, I present my study of nanopores in polyethylene terephthalate (PET), revealing the mechanism for variance in current rectification based on cation species. Second, I demonstrate the mechanism of selective probe capture in bacterial toxin protein α-hemolysin (aHL) using dielectrophoresis. Third, I introduce the first simulation of molecular artificial water channel pillar[5]arene (PAP) and uncover the mechanics of its water transport and self-aggregation properties. Fourth, I characterize the water permeability and ion rejection of truncated human membrane protein aquaporin-1 (AQP) in simulation. Finally, I present MD simulation of truncated AQP as a voltage-gated ionic diode and as the functional element of a double-membrane ionic pump.","abstract_html":"A detailed characterization of the physics of novel nanopore systems has the potential to revolutionize water filtration, nanofluidics, and biomolecule detection technologies. I give my characterizations of five nanopore systems as my dissertation. First, I present my study of nanopores in polyethylene terephthalate (PET), revealing the mechanism for variance in current rectification based on cation species. Second, I demonstrate the mechanism of selective probe capture in bacterial toxin protein α-hemolysin (aHL) using dielectrophoresis. Third, I introduce the first simulation of molecular artificial water channel pillar[5]arene (PAP) and uncover the mechanics of its water transport and self-aggregation properties. Fourth, I characterize the water permeability and ion rejection of truncated human membrane protein aquaporin-1 (AQP) in simulation. Finally, I present MD simulation of truncated AQP as a voltage-gated ionic diode and as the functional element of a double-membrane ionic pump.","abstract_has_math":false,"creators":["Decker, Karl Steven"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Physics","degree_department":null,"school":null,"contributors":["Aksimentiev, Aleksei","Selvin, Paul R.","Tajkhorshid, Emad","Stack, John"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017-09-29T16:37:49Z","date_published":"2017-09-29T16:37:49Z","updated_at":"2026-07-22T22:24:34Z","subjects":["Molecular transport","Nanopore","Biomolecule","Ion current","Filtration"],"languages":["en"],"rights":["Copyright 2017 Karl Decker"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/98107","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Aksimentiev, Aleksei","Selvin, Paul R.","Tajkhorshid, Emad","Stack, John"]},{"key":"dc:creator","label":"Author","values":["Decker, Karl Steven"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2017-09-29T16:37:49Z","2017-06-02","2017-08"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Physics"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Molecular transport","Nanopore","Biomolecule","Ion current","Filtration"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2017 Karl Decker"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/98107"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["A detailed characterization of the physics of novel nanopore systems has the potential to revolutionize water filtration, nanofluidics, and biomolecule detection technologies. 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The submission was exported from vireo on 2017-09-29 without embargo terms","The student, Karl Decker, accepted the attached license on 2017-05-31 at 14:37.","The student, Karl Decker, submitted this Dissertation for approval on 2017-05-31 at 14:45.","This Dissertation was approved for publication on 2017-06-02 at 10:51.","DSpace SAF Submission Ingestion Package generated from Vireo submission #11189 on 2017-09-29 at 11:25:54","Made available in DSpace on 2017-09-29T16:37:49Z (GMT). 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