Portable electrochemical and plasmonic biosensors for biomedical application
type: CreativeWork
description: Portable sensing for point-of-care (POC) has attracted a lot of attention in these years and has been developed in a wide variety for clinical and environmental applications. The idea of POC comes from the advances in portable smart electronic devices and micro-fluid systems which can be integrated and miniaturized into a lab-on-a-chip. Modern electronic devices, like smartphones, smartwatchs or even headsets, can achieve signal generating and receiving by using interfaces like camera, flashlight, audio-jack, micro-USB and wireless module. On the other side, development in the micro-fluid system enables the integration of different diagnosis techniques like separation, quenching, lysing and sensing into a single chip. Polydimethylsiloxane (PDMS) and SU-8 photoresist were commonly used in building such micro-fluid systems, which was first demonstrated by Whiteside's group. Quite a large number of applications were published by coupling such system with optical or electrical sensing techniques. In recent years, paper-based micro-fluid systems have begun to take over the traditional micro-fluid systems mainly due to paper's pump-free and cost-effective property. Some new fabrication methods like wax printing, screen printing and 3D printing were utilized to make such paper-based platforms more attractive. The paper substrate has been verified for use in different sensing stages with all of its properties, such as porous, self-pumping, flexible, anti-oxidation, cost-effective and hydrophilic capabilities. Many sensing techniques have been demonstrated to be coupled with such micro-fluid systems mentioned above for POC applications. Plasmonic and electrochemical methods are the two techniques that will be illustrated in this dissertation. The plasmonic method is new in the sensing area. Plasmon is the oscillation of free electrons at the interface of metal and dielectric material. With the incident of light, the resonance mode will be excited at some certain frequencies …
abstract: Portable sensing for point-of-care (POC) has attracted a lot of attention in these years and has been developed in a wide variety for clinical and environmental applications. The idea of POC comes from the advances in portable smart electronic devices and micro-fluid systems which can be integrated and miniaturized into a lab-on-a-chip. Modern electronic devices, like smartphones, smartwatchs or even headsets, can achieve signal generating and receiving by using interfaces like camera, flashlight, audio-jack, micro-USB and wireless module. On the other side, development in the micro-fluid system enables the integration of different diagnosis techniques like separation, quenching, lysing and sensing into a single chip. Polydimethylsiloxane (PDMS) and SU-8 photoresist were commonly used in building such micro-fluid systems, which was first demonstrated by Whiteside's group. Quite a large number of applications were published by coupling such system with optical or electrical sensing techniques. In recent years, paper-based micro-fluid systems have begun to take over the traditional micro-fluid systems mainly due to paper's pump-free and cost-effective property. Some new fabrication methods like wax printing, screen printing and 3D printing were utilized to make such paper-based platforms more attractive. The paper substrate has been verified for use in different sensing stages with all of its properties, such as porous, self-pumping, flexible, anti-oxidation, cost-effective and hydrophilic capabilities. Many sensing techniques have been demonstrated to be coupled with such micro-fluid systems mentioned above for POC applications. Plasmonic and electrochemical methods are the two techniques that will be illustrated in this dissertation. The plasmonic method is new in the sensing area. Plasmon is the oscillation of free electrons at the interface of metal and dielectric material. With the incident of light, the resonance mode will be excited at some certain frequencies …
author: Wang, Xinhao
language: en
keywords: Electrochemical, Plasmonic
date published: 2017-03-01T16:36:59Z
date modified: 2026-07-22T22:26:37Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/95492