{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/95289"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/95289","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"A stimulus/recording system for optogenetics: circuit, firmware, and software design and implementation","abstract":"An efficient and precise stimulus light delivery and signal readout system is the crucial component in studying optogenetics in a living animal model. In this study, a lightweight, low-cost stimulus/readout system is proposed, designed, fabricated, and tested for optogenetics study of neural activities. The system comprises a photodiode amplifier, LED driver, embedded control system, and desktop control software. The low-noise, precision photodiode amplifier is designed to read the weak photo-current signal associated with neural activities and convert it to proper voltage for signal analysis. The LED driver generates low noise, stable, and constant current flow to drive the stimulus LED light source. The embedded control system is the central control unit that generates the control signals for ADC sampling, pulsing the stimulus LED light. Moreover, it handles all the communications with the desktop control software for command/data exchange. The desktop control software is a graphical user interface that interacts with the experimenter and communicates to the embedded control system. The system includes circuit design and simulation, firmware development for embedded system, 4-layer PCB layout, and a Windows desktop software development using C++ under QT framework. These components will be discussed in detail. The system is integrated and tested in vitro. The result shows that the system is functioning as proposed.","abstract_html":"An efficient and precise stimulus light delivery and signal readout system is the crucial component in studying optogenetics in a living animal model. In this study, a lightweight, low-cost stimulus/readout system is proposed, designed, fabricated, and tested for optogenetics study of neural activities. The system comprises a photodiode amplifier, LED driver, embedded control system, and desktop control software. The low-noise, precision photodiode amplifier is designed to read the weak photo-current signal associated with neural activities and convert it to proper voltage for signal analysis. The LED driver generates low noise, stable, and constant current flow to drive the stimulus LED light source. The embedded control system is the central control unit that generates the control signals for ADC sampling, pulsing the stimulus LED light. Moreover, it handles all the communications with the desktop control software for command/data exchange. The desktop control software is a graphical user interface that interacts with the experimenter and communicates to the embedded control system. The system includes circuit design and simulation, firmware development for embedded system, 4-layer PCB layout, and a Windows desktop software development using C++ under QT framework. These components will be discussed in detail. The system is integrated and tested in vitro. The result shows that the system is functioning as proposed.","abstract_has_math":false,"creators":["Wang, Xinying"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Electrical & Computer Engr","degree_department":null,"school":null,"contributors":["Schutt-Ainé, José E.","Rogers, John A."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017-03-01T15:46:10Z","date_published":"2017-03-01T15:46:10Z","updated_at":"2026-07-22T22:26:37Z","subjects":["Optogenetics","Stimulus recording system","Circuit","Firmware design","Software design"],"languages":["en"],"rights":["Copyright 2016 Xinying Wang"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/95289","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Schutt-Ainé, José E.","Rogers, John A."]},{"key":"dc:creator","label":"Author","values":["Wang, Xinying"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2017-03-01T15:46:10Z","2016-11-29","2016-12"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Electrical & Computer Engr"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Optogenetics","Stimulus recording system","Circuit","Firmware design","Software design"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2016 Xinying Wang"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/95289"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["An efficient and precise stimulus light delivery and signal readout system is the crucial component in studying optogenetics in a living animal model. In this study, a lightweight, low-cost stimulus/readout system is proposed, designed, fabricated, and tested for optogenetics study of neural activities. The system comprises a photodiode amplifier, LED driver, embedded control system, and desktop control software. The low-noise, precision photodiode amplifier is designed to read the weak photo-current signal associated with neural activities and convert it to proper voltage for signal analysis. The LED driver generates low noise, stable, and constant current flow to drive the stimulus LED light source. The embedded control system is the central control unit that generates the control signals for ADC sampling, pulsing the stimulus LED light. Moreover, it handles all the communications with the desktop control software for command/data exchange. The desktop control software is a graphical user interface that interacts with the experimenter and communicates to the embedded control system. The system includes circuit design and simulation, firmware development for embedded system, 4-layer PCB layout, and a Windows desktop software development using C++ under QT framework. These components will be discussed in detail. The system is integrated and tested in vitro. The result shows that the system is functioning as proposed.","Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2017-02-28 without embargo terms","The student, Xinying Wang, accepted the attached license on 2016-11-28 at 12:50.","The student, Xinying Wang, submitted this Thesis for approval on 2016-11-28 at 13:02.","This Thesis was approved for publication on 2016-11-29 at 13:55.","DSpace SAF Submission Ingestion Package generated from Vireo submission #10178 on 2017-02-28 at 14:46:27","Made available in DSpace on 2017-03-01T15:46:10Z (GMT). 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The system comprises a photodiode amplifier, LED driver, embedded control system, and desktop control software. The low-noise, precision photodiode amplifier is designed to read the weak photo-current signal associated with neural activities and convert it to proper voltage for signal analysis. The LED driver generates low noise, stable, and constant current flow to drive the stimulus LED light source. The embedded control system is the central control unit that generates the control signals for ADC sampling, pulsing the stimulus LED light. Moreover, it handles all the communications with the desktop control software for command/data exchange. The desktop control software is a graphical user interface that interacts with the experimenter and communicates to the embedded control system. The system includes circuit design and simulation, firmware development for embedded system, 4-layer PCB layout, and a Windows desktop software development using C++ under QT framework. These components will be discussed in detail. The system is integrated and tested in vitro. The result shows that the system is functioning as proposed.","Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2017-02-28 without embargo terms","The student, Xinying Wang, accepted the attached license on 2016-11-28 at 12:50.","The student, Xinying Wang, submitted this Thesis for approval on 2016-11-28 at 13:02.","This Thesis was approved for publication on 2016-11-29 at 13:55.","DSpace SAF Submission Ingestion Package generated from Vireo submission #10178 on 2017-02-28 at 14:46:27","Made available in DSpace on 2017-03-01T15:46:10Z (GMT). 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