{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/90487"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/90487","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Investigating the epidemiology of Terrapene herpesvirus 1 in freeranging eastern box turtle populations","abstract":"Herpesviruses are ubiquitous, well described pathogens in captive chelonians worldwide, but their importance on free-ranging populations are less defined. In this thesis, a quantitative PCR was developed that detected a 58 base pair segment of the DNA polymerase gene segment of Terrapene herpesvirus 1 (Order: Herpesvirales; Family: Herpesviridae; Subfamily: Alphaherpesvirinae; Genus: Scutavirus). This assay was used to estimate prevalence of herpesvirus infection in 409 free-ranging eastern box turtles (Terrapene carolina carolina) from Tennessee and Illinois. The overall prevalence in this study population was 31.3% (95% confidence interval: 27-36%), with a significantly higher prevalence in July (52.3%; 95% CI: 41-59%) compared to May (13.3%; 95% CI: 5-15%) and September (34.4%; 95% CI: 29-47%). Clinical signs recorded in box turtles were not significantly associated with herpesvirus infection and may be attributed to a latency period. The work presented in this thesis aids in characterizing the epidemiology of herpesvirus in chelonians.","abstract_html":"Herpesviruses are ubiquitous, well described pathogens in captive chelonians worldwide, but their importance on free-ranging populations are less defined. In this thesis, a quantitative PCR was developed that detected a 58 base pair segment of the DNA polymerase gene segment of Terrapene herpesvirus 1 (Order: Herpesvirales; Family: Herpesviridae; Subfamily: Alphaherpesvirinae; Genus: Scutavirus). This assay was used to estimate prevalence of herpesvirus infection in 409 free-ranging eastern box turtles (Terrapene carolina carolina) from Tennessee and Illinois. The overall prevalence in this study population was 31.3% (95% confidence interval: 27-36%), with a significantly higher prevalence in July (52.3%; 95% CI: 41-59%) compared to May (13.3%; 95% CI: 5-15%) and September (34.4%; 95% CI: 29-47%). Clinical signs recorded in box turtles were not significantly associated with herpesvirus infection and may be attributed to a latency period. The work presented in this thesis aids in characterizing the epidemiology of herpesvirus in chelonians.","abstract_has_math":false,"creators":["Kane, Lauren P"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"VMS - Comparative Biosciences","degree_department":null,"school":null,"contributors":["Allender, Matthew C."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2016,"date_issued":"2016-07-07T19:53:05Z","date_published":"2016-07-07T19:53:05Z","updated_at":"2026-07-22T22:26:32Z","subjects":["Epidemiology","herpesvirus","Eastern box turtle","qPCR","Terrapene carolina","disease"],"languages":["en"],"rights":["Copyright 2016 LAUREN P. 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KANE"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/90487"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Herpesviruses are ubiquitous, well described pathogens in captive chelonians worldwide, but their importance on free-ranging populations are less defined. In this thesis, a quantitative PCR was developed that detected a 58 base pair segment of the DNA polymerase gene segment of Terrapene herpesvirus 1 (Order: Herpesvirales; Family: Herpesviridae; Subfamily: Alphaherpesvirinae; Genus: Scutavirus). This assay was used to estimate prevalence of herpesvirus infection in 409 free-ranging eastern box turtles (Terrapene carolina carolina) from Tennessee and Illinois. The overall prevalence in this study population was 31.3% (95% confidence interval: 27-36%), with a significantly higher prevalence in July (52.3%; 95% CI: 41-59%) compared to May (13.3%; 95% CI: 5-15%) and September (34.4%; 95% CI: 29-47%). Clinical signs recorded in box turtles were not significantly associated with herpesvirus infection and may be attributed to a latency period. The work presented in this thesis aids in characterizing the epidemiology of herpesvirus in chelonians.","Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2016-07-07 without embargo terms","The student, Lauren Kane, accepted the attached license on 2016-03-16 at 11:07.","The student, Lauren Kane, submitted this Thesis for approval on 2016-03-16 at 12:02.","This Thesis was approved for publication on 2016-03-18 at 13:11.","DSpace SAF Submission Ingestion Package generated from Vireo submission #9106 on 2016-07-07 at 13:28:16","Made available in DSpace on 2016-07-07T19:53:05Z (GMT). No. of bitstreams: 2 KANE-THESIS-2016.pdf: 11426690 bytes, checksum: 2f84242a145943eac2e9685ad4f7de90 (MD5) LICENSE.txt: 4208 bytes, checksum: 2c4ae08d6f53f8b190e8bbf65dfff302 (MD5) Previous issue date: 2016-03-18"]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Investigating the epidemiology of Terrapene herpesvirus 1 in freeranging eastern box turtle populations"]}]}],"canonical_facts":{"dc:contributor":["Allender, Matthew C."],"dc:creator":["Kane, Lauren P"],"dc:date":["2016-07-07T19:53:05Z","2016-03-18","2016-05"],"dc:description":["Herpesviruses are ubiquitous, well described pathogens in captive chelonians worldwide, but their importance on free-ranging populations are less defined. In this thesis, a quantitative PCR was developed that detected a 58 base pair segment of the DNA polymerase gene segment of Terrapene herpesvirus 1 (Order: Herpesvirales; Family: Herpesviridae; Subfamily: Alphaherpesvirinae; Genus: Scutavirus). This assay was used to estimate prevalence of herpesvirus infection in 409 free-ranging eastern box turtles (Terrapene carolina carolina) from Tennessee and Illinois. The overall prevalence in this study population was 31.3% (95% confidence interval: 27-36%), with a significantly higher prevalence in July (52.3%; 95% CI: 41-59%) compared to May (13.3%; 95% CI: 5-15%) and September (34.4%; 95% CI: 29-47%). Clinical signs recorded in box turtles were not significantly associated with herpesvirus infection and may be attributed to a latency period. The work presented in this thesis aids in characterizing the epidemiology of herpesvirus in chelonians.","Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2016-07-07 without embargo terms","The student, Lauren Kane, accepted the attached license on 2016-03-16 at 11:07.","The student, Lauren Kane, submitted this Thesis for approval on 2016-03-16 at 12:02.","This Thesis was approved for publication on 2016-03-18 at 13:11.","DSpace SAF Submission Ingestion Package generated from Vireo submission #9106 on 2016-07-07 at 13:28:16","Made available in DSpace on 2016-07-07T19:53:05Z (GMT). No. of bitstreams: 2 KANE-THESIS-2016.pdf: 11426690 bytes, checksum: 2f84242a145943eac2e9685ad4f7de90 (MD5) LICENSE.txt: 4208 bytes, checksum: 2c4ae08d6f53f8b190e8bbf65dfff302 (MD5) Previous issue date: 2016-03-18"],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/2142/90487"],"dc:language":["en"],"dc:rights":["Copyright 2016 LAUREN P. KANE"],"dc:subject":["Epidemiology","herpesvirus","Eastern box turtle","qPCR","Terrapene carolina","disease"],"dc:title":["Investigating the epidemiology of Terrapene herpesvirus 1 in freeranging eastern box turtle populations"],"dc:type":["text"],"thesis:degree_discipline":["VMS - Comparative Biosciences"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["M.S."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:26:32Z"}