{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/88317"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/88317","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Micrometer-scale chemical analysis using heated AFM cantilever and mass spectrometer","abstract":"This thesis presents the development of a micrometer-scale chemical analysis method using a heated atomic force microscope(AFM) cantilever and mass spectrometer. Simulations investigate the underlying transport mechanisms within the system and the impact of various design parameters. The way to optimize the system is suggested based on the simulation results. A heated microcantilever is used to thermally desorb a micrometer-sized sample by applying thermal energy. Thermally desorbed species are transported through the micro capillary to the vacuum chamber and are deposited onto the plate inside the chamber. The collected species on the plate can be analyzed by a mass spectrometer or fluorescence microscope. The microcantilever is resistively heated and can be operated up to 1000 °C, which enables applications to various samples with a high decomposition or boiling temperature. In the present work, a caffeine sample and rhodamine B sample were successfully analyzed. The caffeine sample was detected by MALDI mass spectrometry, and rhodamine B sample was detected by fluorescence microscopy.","abstract_html":"This thesis presents the development of a micrometer-scale chemical analysis method using a heated atomic force microscope(AFM) cantilever and mass spectrometer. Simulations investigate the underlying transport mechanisms within the system and the impact of various design parameters. The way to optimize the system is suggested based on the simulation results. A heated microcantilever is used to thermally desorb a micrometer-sized sample by applying thermal energy. Thermally desorbed species are transported through the micro capillary to the vacuum chamber and are deposited onto the plate inside the chamber. The collected species on the plate can be analyzed by a mass spectrometer or fluorescence microscope. The microcantilever is resistively heated and can be operated up to 1000 °C, which enables applications to various samples with a high decomposition or boiling temperature. In the present work, a caffeine sample and rhodamine B sample were successfully analyzed. The caffeine sample was detected by MALDI mass spectrometry, and rhodamine B sample was detected by fluorescence microscopy.","abstract_has_math":false,"creators":["Moon, Hyunkyu"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Mechanical Engineering","degree_department":null,"school":null,"contributors":["King, William Paul"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-29T21:08:26Z","date_published":"2015-09-29T21:08:26Z","updated_at":"2026-07-22T22:26:32Z","subjects":["atomic force microscopy (AFM)","mass spectrometer (MS)","Matrix-assisted laser desorption/ionisation (MALDI)","heated cantilever","chemical identification"],"languages":["en"],"rights":["Copyright 2015 Hyunkyu Moon"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/88317","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["King, William Paul"]},{"key":"dc:creator","label":"Author","values":["Moon, Hyunkyu"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-29T21:08:26Z","2017-09-30T09:15:22Z","2015-08","2015-07-24","2015-8"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Mechanical Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["atomic force microscopy (AFM)","mass spectrometer (MS)","Matrix-assisted laser desorption/ionisation (MALDI)","heated cantilever","chemical identification"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2015 Hyunkyu Moon"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/88317"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["This thesis presents the development of a micrometer-scale chemical analysis method using a heated atomic force microscope(AFM) cantilever and mass spectrometer. Simulations investigate the underlying transport mechanisms within the system and the impact of various design parameters. The way to optimize the system is suggested based on the simulation results. A heated microcantilever is used to thermally desorb a micrometer-sized sample by applying thermal energy. Thermally desorbed species are transported through the micro capillary to the vacuum chamber and are deposited onto the plate inside the chamber. The collected species on the plate can be analyzed by a mass spectrometer or fluorescence microscope. The microcantilever is resistively heated and can be operated up to 1000 °C, which enables applications to various samples with a high decomposition or boiling temperature. In the present work, a caffeine sample and rhodamine B sample were successfully analyzed. The caffeine sample was detected by MALDI mass spectrometry, and rhodamine B sample was detected by fluorescence microscopy.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-08-01","The student, Hyunkyu Moon, accepted the attached license on 2015-07-23 at 22:23.","The student, Hyunkyu Moon, submitted this Thesis for approval on 2015-07-23 at 22:37.","This Thesis was approved for publication on 2015-07-24 at 07:30.","DSpace SAF Submission Ingestion Package generated from Vireo submission #8621 on 2015-09-29 at 15:06:52","Made available in DSpace on 2015-09-29T21:08:26Z (GMT). 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Simulations investigate the underlying transport mechanisms within the system and the impact of various design parameters. The way to optimize the system is suggested based on the simulation results. A heated microcantilever is used to thermally desorb a micrometer-sized sample by applying thermal energy. Thermally desorbed species are transported through the micro capillary to the vacuum chamber and are deposited onto the plate inside the chamber. The collected species on the plate can be analyzed by a mass spectrometer or fluorescence microscope. The microcantilever is resistively heated and can be operated up to 1000 °C, which enables applications to various samples with a high decomposition or boiling temperature. In the present work, a caffeine sample and rhodamine B sample were successfully analyzed. The caffeine sample was detected by MALDI mass spectrometry, and rhodamine B sample was detected by fluorescence microscopy.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-08-01","The student, Hyunkyu Moon, accepted the attached license on 2015-07-23 at 22:23.","The student, Hyunkyu Moon, submitted this Thesis for approval on 2015-07-23 at 22:37.","This Thesis was approved for publication on 2015-07-24 at 07:30.","DSpace SAF Submission Ingestion Package generated from Vireo submission #8621 on 2015-09-29 at 15:06:52","Made available in DSpace on 2015-09-29T21:08:26Z (GMT). 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