{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/86365"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/86365","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Regional Fat Distribution, Physical Activity and Hormonal Factors in Adults With Type 2 Diabetes","abstract":"This study evaluated the association between central fat (CF) and both plasma hormones and physical activity (PA) in 17 men and 23 women (mean age 62 years, body mass index 31 kg/m2) with type 2 diabetes. Dual energy X-ray absorptiometry was used to assess central abdominal fat (CAF), abdominal fat (AF), and trunk fat (TF). Testosterone, free testosterone (FT), estradiol and insulin-like growth factor I (IGF-I) were assessed by radioimmunoassay. Sex-hormone binding globulin (SHBG), and androgeneicity index (AI) were calculated from testosterone and FT. Leisure, occupational, household, non-leisure and total physical activity (TPA) at time1 (15--22 years of age), time2 (23--34 years), time3 (35--50 years), and time4 (past 12 months) were assessed by a historical PA questionnaire. Results showed that (a) participants had lower values of testosterone, FT, and IGF-I, and higher values of SHBG than healthy individuals; (b) in men, CAF and TF were negatively associated with occupational, household, non-leisure, and TPA (r = -0.47 to -0.55). PA at time3 and time4 were negatively associated with TF (r = -0.51 and -0.54, respectively). Total and household activities at time3 were negatively associated with waist circumference (r = -0.53 and -0.57, respectively); (c) in women, CAF and TF were positively associated with household (r = 0.54 and 0.56) and non-leisure (r = 0.41 and 0.42, respectively) activity. AF was positively associated with household (r = 0.42) but negatively associated with leisure activity (r = -0.42); (d) in women, estradiol was negatively associated with AF (r = -0.66). In a subsample of women on estrogen replacement (n = 10), SHBG and estradiol were negatively associated with CAF (r = -0.75 and -0.65) and TF (r = -0.69 and -0.65, respectively). Al was positively associated with CAF (r = 0.69) and TF ( r = 0.68). In conclusion, PA and CF are negatively associated in older men with type2 diabetes. The positive associations in women were attributed to measurement error. The association between CF and both SHBG and AI in women might be dependent upon hormonal replacement therapy.","abstract_html":"This study evaluated the association between central fat (CF) and both plasma hormones and physical activity (PA) in 17 men and 23 women (mean age 62 years, body mass index 31 kg/m2) with type 2 diabetes. Dual energy X-ray absorptiometry was used to assess central abdominal fat (CAF), abdominal fat (AF), and trunk fat (TF). Testosterone, free testosterone (FT), estradiol and insulin-like growth factor I (IGF-I) were assessed by radioimmunoassay. Sex-hormone binding globulin (SHBG), and androgeneicity index (AI) were calculated from testosterone and FT. Leisure, occupational, household, non-leisure and total physical activity (TPA) at time1 (15--22 years of age), time2 (23--34 years), time3 (35--50 years), and time4 (past 12 months) were assessed by a historical PA questionnaire. Results showed that (a) participants had lower values of testosterone, FT, and IGF-I, and higher values of SHBG than healthy individuals; (b) in men, CAF and TF were negatively associated with occupational, household, non-leisure, and TPA (r = -0.47 to -0.55). PA at time3 and time4 were negatively associated with TF (r = -0.51 and -0.54, respectively). Total and household activities at time3 were negatively associated with waist circumference (r = -0.53 and -0.57, respectively); (c) in women, CAF and TF were positively associated with household (r = 0.54 and 0.56) and non-leisure (r = 0.41 and 0.42, respectively) activity. AF was positively associated with household (r = 0.42) but negatively associated with leisure activity (r = -0.42); (d) in women, estradiol was negatively associated with AF (r = -0.66). In a subsample of women on estrogen replacement (n = 10), SHBG and estradiol were negatively associated with CAF (r = -0.75 and -0.65) and TF (r = -0.69 and -0.65, respectively). Al was positively associated with CAF (r = 0.69) and TF ( r = 0.68). In conclusion, PA and CF are negatively associated in older men with type2 diabetes. The positive associations in women were attributed to measurement error. The association between CF and both SHBG and AI in women might be dependent upon hormonal replacement therapy.","abstract_has_math":false,"creators":["Pascale, Angelo"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Kinesiology and Community Health","degree_department":null,"school":null,"contributors":["Richard A. Washburn"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-28T15:04:18Z","date_published":"2015-09-28T15:04:18Z","updated_at":"2026-07-22T22:26:27Z","subjects":["Health Sciences, Public Health"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI3070501"],"render_values":[{"text":"(MiAaPQ)AAI3070501","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/86365","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Richard A. Washburn"]},{"key":"dc:creator","label":"Author","values":["Pascale, Angelo"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-28T15:04:18Z","10000-01-01","2002"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Kinesiology and Community Health"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Health Sciences, Public Health"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/86365","(MiAaPQ)AAI3070501"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["This study evaluated the association between central fat (CF) and both plasma hormones and physical activity (PA) in 17 men and 23 women (mean age 62 years, body mass index 31 kg/m2) with type 2 diabetes. Dual energy X-ray absorptiometry was used to assess central abdominal fat (CAF), abdominal fat (AF), and trunk fat (TF). Testosterone, free testosterone (FT), estradiol and insulin-like growth factor I (IGF-I) were assessed by radioimmunoassay. Sex-hormone binding globulin (SHBG), and androgeneicity index (AI) were calculated from testosterone and FT. Leisure, occupational, household, non-leisure and total physical activity (TPA) at time1 (15--22 years of age), time2 (23--34 years), time3 (35--50 years), and time4 (past 12 months) were assessed by a historical PA questionnaire. Results showed that (a) participants had lower values of testosterone, FT, and IGF-I, and higher values of SHBG than healthy individuals; (b) in men, CAF and TF were negatively associated with occupational, household, non-leisure, and TPA (r = -0.47 to -0.55). PA at time3 and time4 were negatively associated with TF (r = -0.51 and -0.54, respectively). Total and household activities at time3 were negatively associated with waist circumference (r = -0.53 and -0.57, respectively); (c) in women, CAF and TF were positively associated with household (r = 0.54 and 0.56) and non-leisure (r = 0.41 and 0.42, respectively) activity. AF was positively associated with household (r = 0.42) but negatively associated with leisure activity (r = -0.42); (d) in women, estradiol was negatively associated with AF (r = -0.66). In a subsample of women on estrogen replacement (n = 10), SHBG and estradiol were negatively associated with CAF (r = -0.75 and -0.65) and TF (r = -0.69 and -0.65, respectively). Al was positively associated with CAF (r = 0.69) and TF ( r = 0.68). In conclusion, PA and CF are negatively associated in older men with type2 diabetes. The positive associations in women were attributed to measurement error. The association between CF and both SHBG and AI in women might be dependent upon hormonal replacement therapy.","Made available in DSpace on 2015-09-28T15:04:18Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3070501.pdf: 8010912 bytes, checksum: e98f8f5cb567e2172a606fcc156c6499 (MD5) Previous issue date: 2002","Embargo set by: Seth Robbins for item 87646 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","172 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002."]},{"key":"dc:title","label":"Title","values":["Regional Fat Distribution, Physical Activity and Hormonal Factors in Adults With Type 2 Diabetes"]}]}],"canonical_facts":{"dc:contributor":["Richard A. Washburn"],"dc:creator":["Pascale, Angelo"],"dc:date":["2015-09-28T15:04:18Z","10000-01-01","2002"],"dc:description":["This study evaluated the association between central fat (CF) and both plasma hormones and physical activity (PA) in 17 men and 23 women (mean age 62 years, body mass index 31 kg/m2) with type 2 diabetes. Dual energy X-ray absorptiometry was used to assess central abdominal fat (CAF), abdominal fat (AF), and trunk fat (TF). Testosterone, free testosterone (FT), estradiol and insulin-like growth factor I (IGF-I) were assessed by radioimmunoassay. Sex-hormone binding globulin (SHBG), and androgeneicity index (AI) were calculated from testosterone and FT. Leisure, occupational, household, non-leisure and total physical activity (TPA) at time1 (15--22 years of age), time2 (23--34 years), time3 (35--50 years), and time4 (past 12 months) were assessed by a historical PA questionnaire. Results showed that (a) participants had lower values of testosterone, FT, and IGF-I, and higher values of SHBG than healthy individuals; (b) in men, CAF and TF were negatively associated with occupational, household, non-leisure, and TPA (r = -0.47 to -0.55). PA at time3 and time4 were negatively associated with TF (r = -0.51 and -0.54, respectively). Total and household activities at time3 were negatively associated with waist circumference (r = -0.53 and -0.57, respectively); (c) in women, CAF and TF were positively associated with household (r = 0.54 and 0.56) and non-leisure (r = 0.41 and 0.42, respectively) activity. AF was positively associated with household (r = 0.42) but negatively associated with leisure activity (r = -0.42); (d) in women, estradiol was negatively associated with AF (r = -0.66). In a subsample of women on estrogen replacement (n = 10), SHBG and estradiol were negatively associated with CAF (r = -0.75 and -0.65) and TF (r = -0.69 and -0.65, respectively). Al was positively associated with CAF (r = 0.69) and TF ( r = 0.68). In conclusion, PA and CF are negatively associated in older men with type2 diabetes. The positive associations in women were attributed to measurement error. The association between CF and both SHBG and AI in women might be dependent upon hormonal replacement therapy.","Made available in DSpace on 2015-09-28T15:04:18Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3070501.pdf: 8010912 bytes, checksum: e98f8f5cb567e2172a606fcc156c6499 (MD5) Previous issue date: 2002","Embargo set by: Seth Robbins for item 87646 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","172 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002."],"dc:identifier":["http://hdl.handle.net/2142/86365","(MiAaPQ)AAI3070501"],"dc:language":["eng"],"dc:subject":["Health Sciences, Public Health"],"dc:title":["Regional Fat Distribution, Physical Activity and Hormonal Factors in Adults With Type 2 Diabetes"],"dc:type":["text"],"thesis:degree_discipline":["Kinesiology and Community Health"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:26:27Z"}