{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/85897"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/85897","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Identifying Tumor Vascular Permeability Heterogeneity Using Reduced Encoding Techniques","abstract":"\"In our model, female Sprague Dawley rats with N-ethyl-N-nitrosourea (ENU) induced mammary tumors imaged with fast T1-weighted gradient echo DCE MRI following a Gd-DTPA injection, there is a window of resolutions that detects similar PS \"\"hot spots\"\" compared to those obtained from the clinical imager resolution. The top five PS \"\"hot spots\"\" obtained from 469 mum resolution FFT are statistically different from those at 938 mum resolution FFT, p = 0.0014, and 2500 mum resolution FFT, p < 0.0001. Keyhole when compared with a FFT of similar resolution does not detect PS \"\"hot spots\"\" of similar value, p = 0.0002. PS \"\"hot spots\"\" obtained from RIGR compared to those from FFT are statistically the same value, p = 0.2734, but do not statistically agree on the location of mapped values. The top five Kp↔t/VT \"\"hot spots\"\" and their corresponding ve can statistically differentiate invasive ductal carcinoma from non-invasive papillary carcinoma for the 469 mum and 938 mum resolution, p = 0.0017 and p = 0.0047, respectively, but not for 2500 mum resolution, p = 0.9008.\"","abstract_html":""In our model, female Sprague Dawley rats with N-ethyl-N-nitrosourea (ENU) induced mammary tumors imaged with fast T1-weighted gradient echo DCE MRI following a Gd-DTPA injection, there is a window of resolutions that detects similar PS ""hot spots"" compared to those obtained from the clinical imager resolution. The top five PS ""hot spots"" obtained from 469 mum resolution FFT are statistically different from those at 938 mum resolution FFT, p = 0.0014, and 2500 mum resolution FFT, p < 0.0001. Keyhole when compared with a FFT of similar resolution does not detect PS ""hot spots"" of similar value, p = 0.0002. PS ""hot spots"" obtained from RIGR compared to those from FFT are statistically the same value, p = 0.2734, but do not statistically agree on the location of mapped values. The top five Kp&harr;t/VT ""hot spots"" and their corresponding ve can statistically differentiate invasive ductal carcinoma from non-invasive papillary carcinoma for the 469 mum and 938 mum resolution, p = 0.0017 and p = 0.0047, respectively, but not for 2500 mum resolution, p = 0.9008."","abstract_has_math":false,"creators":["Aref, Michael"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Nuclear Engineering","degree_department":null,"school":null,"contributors":["Erik C. Wiener"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-28T14:50:57Z","date_published":"2015-09-28T14:50:57Z","updated_at":"2026-07-22T22:26:26Z","subjects":["Health Sciences, Radiology"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI3101793"],"render_values":[{"text":"(MiAaPQ)AAI3101793","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/85897","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Erik C. 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The top five PS \"\"hot spots\"\" obtained from 469 mum resolution FFT are statistically different from those at 938 mum resolution FFT, p = 0.0014, and 2500 mum resolution FFT, p < 0.0001. Keyhole when compared with a FFT of similar resolution does not detect PS \"\"hot spots\"\" of similar value, p = 0.0002. PS \"\"hot spots\"\" obtained from RIGR compared to those from FFT are statistically the same value, p = 0.2734, but do not statistically agree on the location of mapped values. The top five Kp↔t/VT \"\"hot spots\"\" and their corresponding ve can statistically differentiate invasive ductal carcinoma from non-invasive papillary carcinoma for the 469 mum and 938 mum resolution, p = 0.0017 and p = 0.0047, respectively, but not for 2500 mum resolution, p = 0.9008.\"","Made available in DSpace on 2015-09-28T14:50:57Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3101793.pdf: 4947771 bytes, checksum: 48e382a0653a90569426e63e1f0833b2 (MD5) Previous issue date: 2003","Embargo set by: Seth Robbins for item 87178 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","126 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2003."]},{"key":"dc:title","label":"Title","values":["Identifying Tumor Vascular Permeability Heterogeneity Using Reduced Encoding Techniques"]}]}],"canonical_facts":{"dc:contributor":["Erik C. Wiener"],"dc:creator":["Aref, Michael"],"dc:date":["2015-09-28T14:50:57Z","10000-01-01","2003"],"dc:description":["\"In our model, female Sprague Dawley rats with N-ethyl-N-nitrosourea (ENU) induced mammary tumors imaged with fast T1-weighted gradient echo DCE MRI following a Gd-DTPA injection, there is a window of resolutions that detects similar PS \"\"hot spots\"\" compared to those obtained from the clinical imager resolution. The top five PS \"\"hot spots\"\" obtained from 469 mum resolution FFT are statistically different from those at 938 mum resolution FFT, p = 0.0014, and 2500 mum resolution FFT, p < 0.0001. Keyhole when compared with a FFT of similar resolution does not detect PS \"\"hot spots\"\" of similar value, p = 0.0002. PS \"\"hot spots\"\" obtained from RIGR compared to those from FFT are statistically the same value, p = 0.2734, but do not statistically agree on the location of mapped values. The top five Kp↔t/VT \"\"hot spots\"\" and their corresponding ve can statistically differentiate invasive ductal carcinoma from non-invasive papillary carcinoma for the 469 mum and 938 mum resolution, p = 0.0017 and p = 0.0047, respectively, but not for 2500 mum resolution, p = 0.9008.\"","Made available in DSpace on 2015-09-28T14:50:57Z (GMT). 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